Probe for diagnosing infectious disease

ABSTRACT

DNA probes for diagnosing infectious diseases involving Staphylococcus aureus and methods of using such probes are provided.

TECHNICAL FIELD

The present invention relates to probes, prepared by making use of causative bacteria of infectious diseases, which are useful for detecting and identifying the causative bacteria.

BACKGROUND ART

In pathology, infection is defined as invasion and establishment of a foothold for growth in an organism by a pathogenic organism (hereinafter referred to as "bacteria"), then the outbreak of disease depends upon the interrelationship between the resistance of host and the virulence of bacteria.

In the infectious diseases, improvement in treatment methods of bateremia have been raised as an important issue. That is to say, bacteremia is not a disease caused by a particular bacterium, but is caused by emergence and habitancy of the various bacteria in blood, then onset thereof is clinically suspected when fever of about 40° C. persists for two or more days. If a patient is an infant or is suffering from terminal cancer with weakened resistance, the patient may die in one or two days, therefore, the bacteremia is a serious and urgent disease, and the improvement in treatment methods thereof have been awaited.

In the infectious disease, phagocytes including neutrophils, monocytes and macrophages primarily work in defense of the body. Emergence of bacteria in the blood is thought as invasion of predominant bacteria which have emerged from the tissue of the phagocyte. Bacteremia is a state wherein the bacteria is emerged into the blood, and a large amount of antibiotic is administrated to treat it wherein the causative bacteria is sensitive to the antibiotic. Generally, since antibiotics lower the functions of the internal organs such as liver, it is necessary to pay an attention to reduce an administration of an ineffective antibiotic to a patient in a serious state.

When bacteremia is defined as a case wherein phagocytesis of cells can not overcome the virulence of bacteria, then the bacteria spread in the body through the blood, bacteremia with serious symptoms due to toxins produced by the bacteria is called as sepsis. Proof of sepsis, in the other word, establishment of the diagnosis requires a check on the items of 1) clinical symptoms, 2) culturing of specimen, 3) gram-staining of the bacteria contained in the specimen, and 4) shock state, then, upon completing the check of these items, the treatment method is determined. Accordingly, to quickly and reliably identify the bacteria have been awaited in the art.

In the present method for detecting and identifying bacteria in a bacteremia-specimen, it is a common procedure to identify in selective medium a specimen which have positive signal in a routine process of culture bottle. However, to successfuly culture the bacteria from these blood specimen is quite difficult, then, if a large dose of antibiotics is administrated when bacteremia was suspected, bacteria in the blood will not be cultured and grown in many cases, therefore, the rate of culture bottle positive case become extremely low.

Although available sub-routine methods include instrumental analysis of constituents and metabolic products of bacteria (Yoshimi Benno, "Quick identification of bacteria with gas chromatography", Rinsho Kensa, Vol. 29, No.12, November 1985, Igaku Shoin ed.), a method utilizing specific antibody (Japanese Patent Provisional Publication No. 60-224068), and a hybridization method utilizing specificity of DNA (Japanese Phase Patent Provisional Publication No. 61-502376) have been developed, any of which are required to separate the bacteria and culture it. On the other hand, as a method established based on the function of phagocytes in infectious diseases, there is a method to examine, under an optical microscope, a stained smear of buffy coat wherein leukocyte of the blood sample is concentrated. Generally speaking, although the rate of detection of bacteria in buffy coat specimens from adult bacteremia patients is 30% at most, which is similar to that in earlobe blood specimens, it was reported that bacteria had been detected in seven cases of ten cases (70%) in newborn patients, therefore, an information concerning the presence of a bacteria in peripheral blood to be obtained by microscope examination on smear is an important for treatment.

Since the conventional methods necessiate the pretreatment which requires at least three to four days in total containing one to two day(s) for selective isolation of bacteria from a specimen, one day for cultivation, and one or more day(s) for fixation, and the culture thereof is continued in practice until the bacteria grow, the culture will needs one week or more even for C.B.-positive cases, therefore, this was a factor in high mortality of C.B.-positive patients being treated by the conventional methods. For example, according to the a report published in "The Journal of the Japanese Association for Infectious Diseases", Vol.58, No.2, p.122, 1984, even though the blood culture positive rate was 28.6% (163 cases/569 cases), the mortality was as high as 84.6% (138 cases/163 cases).

Further, it may be impossible to distinguish contamination at the cultivation by indigenous bacteria. For example, Staphylococcus epidermides, which is one of Staphylococci and is the causative bacterium of bacteremia, stayed in the skin of the normal person, then, there is a risk on contamination of a specimen with this bacterium when a needle is inserted into the skin.

As an important matter, under such circumstances above, since many bacteria in a specimen to be cultured have been incorporated into said phagocyte and are dead or stationary immobilized, the number of growable bacteria is small even under appropriate conditions for cultivation, thereby, the actual detection rate of bacteria through culture specimen is as low as about 10%. In the other word, at this moment, 90% of the examined blood, which have been cultured for further one or more day(s), of the patient suspected clinically as suffering with bacteremia can not clarify the presence of bacteria.

In light of the situation above, the present practice depends on a treatment to be started when bacteremia is clinically suspected without awaiting the detection results, that is to say, a trial and error method wherein an antibiotic having broad spectrum is administrated first, and if the antibiotic is not effective after one or two day(s), another antibiotic will be tried.

According to the method to stain the bacteria in the specimen, the constituents of the living body are also stained together with bacteria, therefore, experience to quickly identify bacteria according to thier image through microscope is required, then there may be cases that can be hardly diagnosed as bacteremia.

Although bacteremia is a disease wherein a rapid and exact diagnosis have been required, the conventional diagnosis method can not respond to such requirements.

DISCLOSURE OF INVENTION

The present invention was established in view of the problems in the art, and is directed to a probe having a specific reactivity with DNA or RNA obtained from primary causative bacteria of the infectious diseases, then provide a genetic information by analyzing the base sequence of DNA in the probe.

By the probe of the present invention, for example, a causative bacteria of the infectious diseases is detected rapidly and exactly, without cultivating/proliferating the bacteria, through a detection of DNA held in the causative bacteria digested and incorporated gradually with the phagocyte. Then, if primers are designed by referring to an information on base sequence of these probes, causative bacteria can identify, without the hybridization, by amplifying the DNA with PCR technique.

When non-radioactive probe, for example, biotinylated probe is used for hybridization, since such probe can be detected with an optical microscope in a conventional laboratory without radio isotope handling facilities, the detection process would be rapid and simple.

BRIEF DESCRIPTION OF DRAWINGS

FIG. 1 is a restriction enzyme map of HindIII fragment on probe for detecting Staphylococcus aureus.

FIG. 2 is a restriction enzyme map of HindIII fragment on probe for detecting Staphylococcus epidermidis.

FIG. 3 is a restriction enzyme map of HindIII fragment on probe for detecting Enterococcus faecalis.

FIG. 4 is a restriction enzyme map of HindIII fragment on probe for detecting Pseudomonas aeruginosa.

FIG. 5 is a restriction enzyme map of HindIII fragment on probe for detecting Escherichia coli.

FIG. 6 is a restriction enzyme map of HindIII fragment on probe for detecting Enterobacter cloacae and Klebsiella pneumonia.

BEST MODE FOR CARRYING OUT THE INVENTION

Examples on probes prepared from Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis, Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae and Enterobacter cloacae (J. Infection, vol. 26, pp.159-170 (1993), J. Clin. Microbiol., vol.31., pp.552-557 (1993)), respectively listed as relatively popular causative bacteria of the infectious diseases, especially bacteremia were described as follows.

EXAMPLE 1 Preparation of DNA Probe from Causative Bacteria of Infectious Diseases

(1) Isolation of Causative Bacteria of Infectious Diseases

Blood collected from the patient who have been suffered with targeted diseases were applied to Blood Culture Method (BBC System: Blood Culture System; Roche) and to a conventional identification kit (Api 20, Apistaf, Apistlep 20: Bio-Meryu), and the each causative bacterium was isolated and identified according to the manual of said kit.

(2) Extraction and Purification of Genomic DNA from Isolated Strain

Strains isolated in the above (1) was cultivated overnight in BHI (Brain Heart Infusion) medium, collected the cultivated bacteria, added thereto achromopeptidase in stead of lysozyme, then, Genomic DNA was extracted according to Saito-Miura Method ("Preparation of Transforming Deoxyribonucleic Acid by Phenol Treatment", Biochem. Biophys. Arta. vol. 72, pp.619-629), and extracted DNA was digested with restriction enzyme HindIII and was random cloned into vector pBR322.

(3) Selection of Probe having Specificity to Species of Origin Bacteria

Escherichia coli containing each clone prepared according to Manual of Maniatis (T. Maniatis, et al., "Molecular Cloning (A Laboratory Manual)", Cold Spring Harbour Laboratory (1982)) was cultivated with small scale culture, and obtained plasmids containing each clone.

These plasmids were digested with restriction enzyme HindIII, thereby inserts were separated completely from plasmids with 1% agarose-gel electrophoresis (Myupid: Cosmo-Bio), then, were transcribed to nylon membrane with Southern-Transfer Technique (Paul Biodine A: Paul), and were cross-hybridized with a probe prepared by labelling ³² P-dCTP (Amersham) through nick-translation to chromosome DNA from each bacteria species aforelisted.

In this hybridization, a probe which did not cross-react with any insert except for a probe prepared from the origin species thereof was selected as a probe containing DNA fragment which is specific to causative bacteria of the infectious diseases.

With regard to probes prepared from Escherichia coli, Klebsiella pneumoniae, Enterobacter cloacae, since these bacteria are belonged to the same group (enteric bacteria; Gram negative aerobic bacillus) as a causative bacteria of bacteremia (See, J. Infection, vol. 26, pp.159-170 (1993), J. Clin. Microbiol., vol.31., pp. 552-557 (1993), supra), and the cross-reaction had been confirmed among said three bacteria in the foregoing series experiments on the specificity, each probe prepared from one of said three bacteria was designated as a probe for detecting all these bacteria as a relevant bacteria.

Probes (denotation) selected from each species through the foregoing methods are listed in the following Table 1.

                  TABLE 1                                                          ______________________________________                                         SPECIES          DENOTATION                                                    ______________________________________                                         Staphylococcus aureus                                                                           SA-7, SA-24, SA-36, SA-77                                     Staphylococcus epidermidis                                                                      SE-3, SE-22, SE-32, SE-37                                     Enterococcus faecalis                                                                           S2-1, S2-3, S2-7, S2-27                                       Pseudomonas aeruginosa                                                                          P2-2, P2-7, P2-17, P4-5                                       Escherichia coli EC-24, EC-34, EC-39, EC-625                                   Klebsiella pneumoniae                                                                           KI-50                                                         Enterobacter cloacae                                                                            ET-12, ET-49                                                  ______________________________________                                    

Restriction enzyme maps of each probe were also illustrated in FIGS. 1-6 respectively.

EXAMPLE 2 Evaluation on Species-Specificity of Each DNA Probe

Reactivity between each probe and DNA from causative bacteria of infectious diseases were examined acooding to the following method. po First of all, as subject strains for an examination, clinical isolates of Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis, Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, and Enterobacter cloacae were isolated according to the method of Example 1 (1) above.

Then, DNA of each clinical isolate were extracted according to the method of Example 1 (2), and samples for dot-blot-hybridization were obtained by spotting certain amount (e.g., 5 μl) of DNA to nylon filter and selecting the isolates denatured with alkaline. Hybridization on DNA probes prepared from each subjected bacterium and labelled with biotin (Bio-dUTP; BRL) were performed overnight according to Manual of Maniatis, supra, under the condition of 45% formamide, 5×SSC, 42° C.

Samples obtained through overnight hybridization were washed twice with 0.1×SSC, 0.1% SDS for 20 minutes at 55° C., then, were detected the color reaction with Streptavidin-ALP conjugates (BRL), and evaluated the hybridization.

Experimental results on reactivity between each probe and DNA of each clinical isolate are illustrated in the following table 2 (i)-(vi). With regard to a denotation in the tables, denotation of "+" refers to the presence of a signal on hybridization, while that of "-" refers to the absence of a signal on hybridization.

                  TABLE 2 (i)                                                      ______________________________________                                                     SA-7  SA-24    SA-36    SA-77                                      ______________________________________                                         Staphylococcus aureus                                                                        +       +        +      +                                        Staphylococcus epidermidis                                                                   -       -        -      -                                        Enterococcus faecalis                                                                        -       -        -      -                                        Pseudomonas aeruginosa                                                                       -       -        -      -                                        Escherichia coli                                                                             -       -        -      -                                        Klebsiella pneumoniae                                                                        -       -        -      -                                        Enterobacter cloacae                                                                         -       -        -      -                                        ______________________________________                                    

                  TABLE 2 (ii)                                                     ______________________________________                                                     SE-3  SE-22    SE-32    SE-37                                      ______________________________________                                         Staphylococcus aureus                                                                        -       -        -      -                                        Staphylococcus epidermidis                                                                   +       +        +      +                                        Enterococcus faecalis                                                                        -       -        -      -                                        Pseudomonas aeruginosa                                                                       -       -        -      -                                        Escherichia coli                                                                             -       -        -      -                                        Klebsiella pneumoniae                                                                        -       -        -      -                                        Enterobacter cloacae                                                                         -       -        -      -                                        ______________________________________                                    

                  TABLE 2 (iii)                                                    ______________________________________                                                        S2-1 S2-3     S2-7   S2-27                                      ______________________________________                                         Staphylococcus aureus                                                                           -      -        -    -                                        Staphylococcus epidermidis                                                                      -      -        -    -                                        Enterococcus faecalis                                                                           +      +        +    +                                        Pseudomonas aeruginosa                                                                          -      -        -    -                                        Escherichia coli -      -        -    -                                        Klebsiella pneumoniae                                                                           -      -        -    -                                        Enterobacter cloacae                                                                            -      -        -    -                                        ______________________________________                                    

                  TABLE 2 (iv)                                                     ______________________________________                                                        P2-2 P2-7     P2-17  P4-5                                       ______________________________________                                         Staphylococcus aureus                                                                           -      -        -    -                                        Staphylococcus epidermidis                                                                      -      -        -    -                                        Enterococcus faecalis                                                                           -      -        -    -                                        Pseudomonas aeruginosa                                                                          +      +        +    +                                        Escherichia coli -      -        -    -                                        Klebsiella pneumoniae                                                                           -      -        -    -                                        Enterobacter cloacae                                                                            -      -        -    -                                        ______________________________________                                    

                  TABLE 2 (v)                                                      ______________________________________                                                      EC-24 EC-34    EC-39   EC-625                                     ______________________________________                                         Staphylococcus aureus                                                                         -       -        -     -                                        Staphylococcus epidermidis                                                                    -       -        -     -                                        Enterococcus faecalis                                                                         -       -        -     -                                        Pseudomonas aeruginosa                                                                        -       -        -     -                                        Escherichia coli                                                                              +       +        +     +                                        Klebsiella pneumoniae                                                                         +       +        +     +                                        Enterobacter cloacae                                                                          +       +        +     +                                        ______________________________________                                    

                  TABLE 2 (vi)                                                     ______________________________________                                                       ET-12    ET-49   KI-50                                           ______________________________________                                         Staphylococcus aureus                                                                          -          -       -                                           Staphylococcus epidermidis                                                                     -          -       -                                           Enterococcus faecalis                                                                          -          -       -                                           Pseudomonas aeruginosa                                                                         -          -       -                                           Escherichia coli                                                                               +          +       +                                           Klebsiella pneumoniae                                                                          +          +       +                                           Enterobacter cloacae                                                                           +          +       +                                           ______________________________________                                    

Apparently from Table 2 above, each probe have reacted only with DNA obtained from origin strain (or relative strain thereof) and not reacted (hybridized) with any DNA obtained from strains except for strains from the origin strain, therefore, their specificity have been confirmed.

EXAMPLE 3 Analysis of Base Sequence

Base sequence of DNA probes (total 23 probes) of the present invention, which have been confirmed their specificity to the origin species in the Examples 1 and 2, were sequenced according to the following method.

(1) Preparation of Plasmid DNA

Escherichia coli K-12, JM109 transformants, wherein the subcloned insert fragments (to be seqeuenced) is contained in pGem-3Z (Promega), was inoculated in 5 ml of Luria-Bactani Medium (bacto-tryptone, 10 g/lL; bacto-yeast extract, 5 g/lL; NaCl, 10 g/lL; adjusted pH to 7.0 with 5N NaOH) and cultivated overnight.

Culture liquid was centrifuged (5,000 rpm, 5 min.) and collected the bacteria. 100 μl of solution of 50 mM glucose/50 mM Tris-HCl (pH8.0)/10 mM EDTA containing 2.5 mg/ml of lysozyme (Sigma) was added to precipitate, and left at room temperature for five minutes. 0.2M NaOH solution containing 1% of sodium dodecyl sulfate (Sigma) was added to the suspension so obtained and mixed therewith. 150 μl of 5M pottasium acetate solution (pH 4.8) was further added thereto and mixed therewith, then iced for 15 minutes.

Supernatant obtained by centrifugation (15,000 rpm, 15 min.) was treated with phenol/CHCl₃ and added thereto ethanol of two times volume, then precipitate was obtained by centrifugation (12,000 rpm, 5 min.). This precipitate was dissolved in 100 μl of solution of 10 mM Tris-HCl (pH7.5)/0.1 mM EDTA and added thereto 10 mg/ml RNaseA (Sigma) solution, then left it at room temperature for 15 minutes.

300 μl of 0.1M sodium acetate solution (pH 4.8) was added to this preparation and treated with phenol/CHCl₃, then precipitate was obtained by adding ethanol to supernatant. DNA samples were prepared by drying this precipitate and dissolving in 10 μl distilled water.

(2) Pretreatment for Sequencing

Pretreatment for sequencing was performed with AutoRead™ Sequencing Kit (Pharmasia).

Concentration of DNA to become a template was adjusted to 5-10 μg in 32 μl. 32 μl of template DNA was transferred to 1.5 ml mini-tube (Eppendolf), and added thereto 8 μl of 2M NaOH solution, then mixed gently therewith. After instant centrifugation, it was left at room temperature for 10 minutes.

7 μl of 3M sodium acetate (pH 4.8) and 4 μl of distilled water, then 120 μl of ethanol were added thereto then mixed therewith, and left for 15 minutes on dry ice. DNA which have been precipitated by centrifugation for 15 minutes were collected, and supernatant was removed carefully. The precipitate so obtained were washed with 70% ethanol and centrifuged for 10 minutes. Then, the supernatant was removed carefully again and dried the precipitate under the reduced pressure.

The precipitate was dissolved in 10 μl of distilled water, then 2 μl of fluorescent primer (0.42 A₂₆₀ unit/10 ml, 4-6 pmol) M13 Universal Primer; 5'-Fluorescein-d CGACGTTGTAAAACGACGGCCAGT!-3' (SEQ ID NO:24) (1.6 pmol/μl; 0.42 A₂₆₀ unit/ml); M13 Reverse Primer, 5'-Fluorescein-d CAGGAAACAG CTATGAC!-3' (SEQ ID NO:25) (2.1 pmol/μl; 0.42 A₂₆₀ unit/ml)! and 2 μl of saline for annealing were added thereto, and mixed gently.

After instant centrifugation, they were heat-treated at 65° C. for 5 minutes and rapidly transferred it to a circumstance of 37° C. and kept the temperature for 10 minutes. After keeping the temperature, it was left at room temperature for 10 minutes or more and centrifugated instantly. Then, samples were prepared by adding thereto 1 μl of an elongation saline and 3 μl of dimethyl sulfoxide.

Four mini-tubes have been identified with one of marks of "A", "C", "G" and "T", and, according to the mark, 2.5 μl of A Mix (dissolved ddATP with dATP, dCTP, c⁷ dGTP and dTTP), C Mix (dissolved ddCTP with dATP, dCTP, c⁷ dGTP and dTTP), G Mix (dissolved ddGTP with dATP, dCTP, c⁷ dGTP and dTTP), or T Mix (dissolved ddTTP with dATP, dCTP, c⁷ dGTP and dTTP) were poured into each identified tube. Each solution was preserved in freezed condition, and the solution was heated at 37° C. for one minute or more to use it.

2 μl of diluted T7DNA polymerase (Pharmacia; 6-8 units/2 μl) was added to DNA sample, and completely mixed by pipetting or mixing it gently. Immediately after completing the mixing, these mixed solution was poured into 4.5 μl of four-types solution respectively which have kept the certain temperature. Fresh tips were used at the time of pouring.

The solution have been kept for five minutes at 37° C., then 5 μl of termination solution were poured into each reaction-solution. Fresh tips were used for pouring. Immediately after keeping the solution for 2-3 minutes at 90° C., it was cooled on ice. 4-6 μl/lane of the solution was applied to the electrophoresis.

(3) Sequencing on Base Sequence

Sequencing on each base sequence of probes, disclosed in Examples 1 and 2, having the specificity against Staphylococcus aureus or Staphylococcus epidermidis were performed with A.L.F. DNA Sequencer System (Pharmacia) under an electrophoresis condition of 45° C. for 6 hours.

Then, base sequences of the probes (SEQ ID.No.) prepared from each causative bacteria of the infectious diseases and listed in the following table 3 were disclosed in the sequence listing attached hereto.

                  TABLE 3                                                          ______________________________________                                         SPECIES            Probes (SEQ ID. No.)                                        ______________________________________                                         Staphylococcus aureus                                                                             SA-7 (1), SA-24 (2)                                                            SA-36 (3), SA-77 (4)                                        Staphylococcus epidermidis                                                                        SE-3 (5), SE-22 (6)                                                            SE-32 (7), SE-37 (8)                                        Enterococcus faecalis                                                                             S2-1 (9), S2-3 (10)                                                            S2-7 (11), S3-27 (12)                                       Pseudomonas aeruginosa                                                                            P-2 (13), S2-7 (14)                                                            P2-17 (15), P4-5 (16)                                       Escherichia coli   EC-24 (17), EC-34 (18),                                                        EC-39 (19), EC-625 (20)                                     Klebsiella pneumoniae                                                                             KI-50 (23)                                                  Enterobacter cloacae                                                                              ET-12 (21), ET-49 (22)                                      ______________________________________                                    

Thereby, genetic information concerning the specific site of each causative bacteria of the infectious diseases (or relative bacteria thereof) have been clarified.

According to probes of the present invention, for example, causative bacteria of the infectious diseases which have incorporated into the phagocyte can be directly detected, and rapidly and exactly identified without proliferating the bacteria. That is to say, according to the diagnosis using the probe of the present invention, identification of the bacteria can be realized with single specimen, then, reduced the necessary time for diagnosis to about one to two day(s), while the conventional method (with low detection rate) required 3-4 days, and improved remarkably the detection rate. Therefore, this invention can provide an objective factors for the treatment of bacteremia, then realize the effective treatment in the early stage of the infectious diseases, and expect to reduce the mortality.

Then, by clarifying the base sequences of probes which specifically react with primary bacteria of the infectious diseases, these probes can be prepared artifically. Further, a part of information on the analyzed base sequences may be used for rapidly diagnosing the causative bacteria by amplifying DNA of causative bacteria of the infectious diseases in the clinical specimen with PCR technique and primers prepared by making use of said information.

Further, by comparing base sequences of Genomic DNA in the clinical specimen with that of the present invention, rapid identification of the species of the causative bacteria of infectious diseases can be realized.

As stated above, the present invention provide desirable probes for diagnosing the infectious diseases, then expect utilities as a factor to prepare primers for PCR and standard sequence for a comparison with Genomic DNA in the clinical specimen, and further expect an effect to provide valuable hints for preparing and developing the other probes which specifically react with causative bacteria of the infectious diseases.

Then, since the base sequences disclosed in the present application was obtained by random-cloning the Genomic DNA of clinical isolates, utilities of the base sequences of the present invention should be extended to the complementary strands thereof.

Further, although it may be thought that DNA obtained from the wild strains contain the mutated portion, apparently from the disclosure of the Examples above, said mutated DNA portion would not affects the utilities to be derived by the present invention comprising the specificity of the probes of the present invention in the hybridization for a diagnosis of the infectious diseases, and an usage of the information on the base sequences disclosed in the present application to design the primers for PCR technique to realize a rapid diagnosis of the infectious diseases.

    __________________________________________________________________________     SEQUENCE LISTING                                                               (1) GENERAL INFORMATION:                                                       (iii) NUMBER OF SEQUENCES: 25                                                  (2) INFORMATION FOR SEQ ID NO:1:                                               (i) SEQUENCE CHARACTERISTICS:                                                  (A) LENGTH: 8959 base pairs                                                    (B) TYPE: nucleic acid                                                         (C) STRANDEDNESS: double                                                       (D) TOPOLOGY: linear                                                           (ii) MOLECULE TYPE: Genomic DNA                                                (vi) ORIGINAL SOURCE:                                                          (A) ORGANISM: Staphylococcus aureus                                            (B) STRAIN: Clinical Isolate SA- 7                                             (xi) SEQUENCE DESCRIPTION: SEQ ID NO:1:                                        AAGCTTTATCTGCTGAATATACCGCATTTTTTATCTTGTTAATTGTCGGCACATTTTCTT60                 CAATAGTTAAACCTGCTTTGTTAGCTTCTTCTAATAATGCTCGAGTTACTGTTTATTAAA120                TGTTCATTCGCTTTTCAACGACAACTGACGAACCAGTATCTGTTAGCTTAGACGCAACAG180                CGTTAATCTTCTGATTCACCTTAAATTCTACATCTGCTTTTTGAGGCTGCTTACGTAGTG240                TCCCGGTAATTTCATGTGTAAACTTAGATGGGATGTAAATACCTGCAAAATATTTACCCA300                TTTTTATCTCATGATCAGCTTTCTCTCTACTTACAAACTGCCAATCAAAACTTTTATTTT360                TCTTGAGTGTATTAACCATCGTATTACCGACATTAACTTTTTTCCCTCTGATTGTGTCGC420                CTTTATCTTCATTAACGACTGCGACCTTGATGTGTCCCGTGTTGCCATATGGATCCCACA480                TTGCCCATAAGTTAAACCAAGCGTAGAACGATGGCAAAATAGCTAAGCCTGCTAAGATAA540                TCCACACAGCTGGCGTCTTAGCTACTTTCTTCAGATCCATTTTAAATAATTTAAATGCGT600                TCTTCATTGTCACACTCCTATGTAGGAATTATTCATATTTTTTATATATTTTTTGTAAAT660                TAATTTATTTTTGCGTTGTGAATTAGTATAATCAATTTACTGGAAGATATTTAGTCGATT720                GATACCTATCAACTATTTTCAGCATACGATAAATTATAACAAATCATAGTTTATTATCAC780                ACTTAATTATTATATTTTTCAAGGGAGAATACGAAATATGCCTAAAAATAAAATTTTAAT840                TTATTTGCTATCAACTACCCTCGTATTACCTACTTTAGTTTCACCTACCGCTTATGCTGA900                TACACCTCAAAAAGATACTACAGCTAAGACAACATCTCATGATTCAAAAAAATCTAATGA960                CGATGAAACTTCTAAGGATACTACAAGTAAAGATACTGATAAAGCAGACAACAATAATAC1020               AAGTAACCAAGACAATAACGACAAAAAATTTAAAACTATAGACGACAGCACTTCAGACTC1080               TAACAATATCATTGATTTTATTTATAAAGAATTTACCACAAACCAATATAAACCAATTGC1140               TAACCAAAAATAAATACGATGATAATTACTCATTAACAACTTTAATCCAAAACTTATTCA1200               ATTTAAATTCGGATATTTCTGATTACGAACAACCTCGTAATGGCGAAAAGTCAACAAATG1260               ATTCGATAAAAACAGTGACATAGCATCAAAAATGACACTGATACGCAATCATCTAAACAA1320               GATAAAGCAGACAATCAAAAAGCACCTAAATCAAACAATACAAAACCAAGTACATCTAAT1380               AAGCAACCAAATTCGCCAAAGCCAACACAACCTAATCAATCAAATAGTCAACCAGCAAGT1440               GACGATAAAGCAAATCAAAAATCTTCATCGAAAGATAATCAATCAATGTCAGATTCGGCT1500               TTAGACTCTATTTTGGATCAATACAGTGAAGATGCAAAGAAAACACAAAAAGATTATGCA1560               TCTCAATCTAAAAAAGACAAAAATGAAAAATCTAATACAAAGAATCCACAGTTACCAACA1620               CAAGATGAATTGAAACATAAATCTAAACCTGCTCAATCATTCAATAACGATGTTAATCAA1680               AAGGATACACGTGCAACATCATTATTCGAAACAGATCCTAGTATATCTAACAATGATGAT1740               AGCGGACAATTTAACGTTGTTGACTCAAAAGATACACGTCAATTTGTCAAATCAATTGCT1800               AAAGATGCACATCGCATTGGTCAAGATAACGATATTTATGCGTCTGTCATGATTGCCCAA1860               GCAATCTTAGAATCTGACTCAGGTCGTAGTGCTTTAGCTAAGTCACCAAACCATAATTTA1920               TTCGGTATCAAAGGTGCTTTTGAAGGGAATTCTGTTCCTTTTAACACATTAGAAGCTGAT1980               GGTAATAAATTGTATAGTATTAATGCTGGATTCCGAAAATATCCAAGCACGAAAGAATCA2040               CTAAAAGATTACTCTGACCTTATTAAAAATGGTATTGATGGCAATCGAACAATTTATAAA2100               CCAACATGGAAATCGGAAGCCGATTCTTATAAAGATGCAACATCACACTTATCTAAAACA2160               TATGCTACAGATCCAAACTATGCTAAGAAATTAAACAGTATTATTAAACACTATCAATTA2220               ACTCAGTTTGACGATGAACGCATGCCAGATTTAGATAAATATGAACGTTCTATCAAGGAT2280               TATGATGATTCATCAGATGAATTCTGTTCCTTTTAACACATTAGAAGCTGATGGTAATAA2340               ATTGTATAGTATTAATGCTGGATTCCGAAAATATCCAAGCACGAAAGAATCACTAAAAGA2400               TTACTCTGACCTTATTAAAAATGGTATTGATGGCAATCGAACAATTTATAAACCAACATG2460               GAAATCGGAAGCCGATTCTTATAAAGATGCAACATCACACTTATCTAAAACATATGCTAC2520               AGATCCAAACTATGCTAAGAAATTAAACAGTATTATTAAACACTATCAATTAACTCAGTT2580               TGACGATGAACGCATGCCAGATTTAGATAAATATGAACGTTCTATCAAGGATTATGATGA2640               TTCATCAGATGAATTCAAACCTTTCCGCGAGGTATCTGATAGTATGCCATATCCACATGG2700               CCAATGTACTTGGTACGTATATAACCGTATGAAACAATTTGGTACATCTATCTCAGGTGA2760               TTTAGGTGATGCACATAATTGGAATAATCGAGCTCAATACCGTGATTATCAAGTAAGTCA2820               TACACCAAAACGTCATGCTGCTGTTGTATTTGAGGCTGGACAATTTGGTGCAGATCAACA2880               TTACGGTCATGTAGCATTTGTTGAAAAAGTTAACAGTGATGGTTCTATCGTTATTTCAGA2940               TCAATGTTAAAGGATTAGGTATCATTTCTCATAGAACTATCAATGCAGCTGCCGCTGAAG3000               AATTATCATATATTACAGGTAAATAAGTATTATTAAACCCGCAAAATTTATAAGTATAAA3060               CAAGGAGTTCGGACTTAAACATATTTCTGTTCATAAGTCCGATTTCTTATTCAATTAAAC3120               CCGAGGTATTCAGTTCGAACGCCTCGGGTCATTTTATATAAATATATTATTTTATGTTCA3180               AATGTTCCTCATCATATCCGTTTCAATTGTCATCTCACACATTTTATAAATATGAGCAAA3240               TGTACTTATTTTCAAACATTACTGCCTAGCTTTAATTGACGTTATATTAACTATAAACTA3300               CTTTTCCATGACTCTACGGATTCAATGTCACATGAGCGTGATAAAATTTGTTCAATAATA3360               AAGTCATGTTTATCATCTGATCTATCACCAACAGCATCTTCTAAAACAGTAATATAATAG3420               TCTTTATCTACACTTTCTAATGCCGTGCTCAATACAGCTCCACTCGTAGAGACACCCGTT3480               AATACTAAATGATTAATATCATTTGCACGTAAATAAACTTCCAAGTAACTACCTGTAAAT3540               GCGCTAAAGCGTCGCTTAGAAATAATCGGCTCATCTTCTAGTGGTGCTAAATCTTCAAGT3600               ATTCGTGTAGATGCATCTGCTTCAGTAATCGCATATCCTTGAGCTTTAATTGTTGAAAAC3660               ACTTTATTACTCGAGGAGACATCATTAAAATGCTTATCTAACACTAAACGTATGAAAATG3720               ACTGGTATTCGATGTTGTCTTGCTGCTTCAATTGCTCTCTGATTCGCTTTAATAATATTT3780               TTTATTCTAGGTACACTACTCGCTATACTTCTTGCATATCCAAACTAATAGCGCCGTTTT3840               TCGAGACATCTTCATTCTCCTTTACTTCTGTAGTTCTAAGTCGTTAAATTCATTATAACG3900               TTAAAATGATGGACAATCTATTCATTGCATTTTGCATATACTTCACAATAATTTAAGGGG3960               GAAATAAGACGTCTTATATACTTAAAAAAATATATAGATGCTCTTCCCCCAATATAATTA4020               TGCTTTATTTTTCAACTTATTGCGTCGTGATAACCAAATCATTAGTACACCCATTGCACC4080               AACAATTACAGATATCGGCAACCAATGTTCTTTTATCGTTTCCCCGCTTTAGGCAAGATA4140               CATTACCATCAGCATTTAATAATCCACTTAACAATCCATTACCTTTACCAAGTGTTACGT4200               CTTTTCTGGCTTTGGTGTGGGTATATCTGGAATACTGTCTAATAAATTTGATCCTTGATT4260               CATTAAATTTGCTAACTTATTTAAATCCGTTGTTTTCCCATTTTTATTCAATCGATCTAG4320               TAAACTTGGACGATTTACTATTGGTGATAAAATATAGTCTATATCTTTTTTCGTTTGATT4380               GAGTCTCTTTTGTAAATTCAATAAATCATCCGCTTTACCATTCAATGCCGATTTAACTAA4440               ATTAAAAATTTTATTTTGATCTGTTTCTATTTTAGTAATTAAATCTGCCAGTAATTTTGC4500               CTTTTGTCTTTCTATACGTGTTGCTAAAATCGTTTCAATTGCTTGCTTTTTATCTTTGGC4560               ATTATTCAAAATTGCTTTTAATATATCATCTGAAGACGTGTCGCCAGTTGATGCAAAATG4620               TTTCTTCAATTGGTCAACGATTTGGCGATTTGATAATCCTTTATTCGTCCAATCTTTAGC4680               CAATTTATCTGCTTCAGCTTTTCCTAATTTCGTTTGTAAGATTTGAGAAATCAATAGCGA4740               CTTATCTTGTGATTGATCAATCAATGACGTTAATAAATCATCACTCGTTGTCAGAGATAG4800               TTGATCAATATGACGAGTAATTTGATCTGCAATTTGTTGATCTGTTTTACCATCAACACG4860               TATATCTTTTAGAATTTTATCTGCCTCGTCTTTATTAAATATACTTTCTAAAATGCTTTG4920               TGTAGCATACTTTTTATCATCAGTACGTGCAAGTTCTTCCAAAATAATATTTCGTTGACT4980               TTTTATACGCTCTTTCGTCTTATTTACTTCGCTCATTAAGTCTGATTTTTGATTTTTAGG5040               AAGTTGCGTATTTGCAATACGTTGATCTAAAGATTGTAACGTATTCAGTTTATGATATGT5100               GTAATGTTGCGTTGAGGCATTACTTTTAGCCAATTTTTCAATCATAGCATGATTAATTTT5160               ATCGCTTCCTTGTAATTTATCAGTGAGTTGATTACTATGGCTTTGATTCTCTTCATTTGA5220               AAGAAATTTATTTAACACAACATGTCCAGAACCATCATTATTTGGCGTTTTAGCTACTTC5280               ATGATTACTATCTGTTGTAGACACTGCCGGATCTTTCGATGCATCTTTCAATGCATCTTT5340               CGATTTGTGTATTTGCTGATTCAAATGGTCTAGGTCTTCTAACGCCTTATTTACCATTGC5400               TTCATCATTTTTATCATCTTTTTCTCCATATTTTGTTGTAGCCGTTTGTGACATATCATT5460               TTTCATTGCATTAAGATCGTCCTCGCCACTTTGTTGACCCCTATCAACATTTGAAGAAAC5520               CTCATTTAAATCTTTAAGCAATTGATCTAATTTACTGTCTATATCACTTTGACCGTTCAT5580               TTCAGTGTGAGAACTTTTATTTTCTTTGCTATCCAACTCATTAGCTCGTTTTATGATTTC5640               ATCTATTTGCGATGCTGTTTTCGCTTCATTTAGTTGTGCTTTATAATGTGCTTTAGATGA5700               AGCCGATAACTGTTTTAATTGCTCAATTTGACGAATTGCTTTGTCAACTTTGTCTAATAA5760               ATCTTGCTTAGATAATATCTCTTTTGAAATTTCAGTATCCTTTTCAGATGCAGCTTGGGC5820               ATCGTACGGCAAGATATTCGTTAAAATGATACTTGACGCCATCATTGTCGAACACGATAA5880               CTTTACATATAATTGAAACGGTTTCCCTCGATATTTAGCCATCAACATACTCCTTTCTCA5940               CTTACTTCCTTCAAAGAATTACATACTATTATATACCTGTTTACAAGAAATTTACACTTA6000               TCTATCTAGTTATTGTTGTTAGTAATTATCAACTTATTACTTAGCTTATATTTAAGTAAA6060               CAAAAAAGCATGACGTAATATCATATTGTCCATGTCGCTAACATCATATTACGTCAAATC6120               TTTTAAATTAAATGATGCTTTATTTTAGACTGCTTTTTCTTTTTAGCTTTCGAGCGCCTG6180               TTTAAAAACTTGCTCGAATTGTTCACGCGAGATTTCGTGTGCATGTGCTTTTTGTGCTAA6240               TAAAGCATCTCGAAACTGTTGTTGATCTTTCAAACTTTCTAACATTTGTATTAATTGGTC6300               TTTACTTTCCATTGTTATCTCATCATTATGCTCAAATAAGTGCTCTGATAATGTTACTTT6360               AGCATGGTGTGCGGTTTGACGATAACCTAAAATCAACAACTCATAGTCAAACGCTTGTTC6420               CACCGCATTTAAAATTTCATTACCCTCATTGATATCAAGATAAATATCACATAACTGGTA6480               TAGTTCATTTACCCTGTCAATATAATAGATGGTATAAGTGCACATTAGCATATTGATCAA6540               GTTGCATTAGCTTATCAGACATCTCTGTAATAGCAGCGATGTGAAAATTAAAATCTGGTA6600               AAGTTTCAACCAATACCTTGATGTTACGAAGTTGATCCGAGTTAGTTAATATTACAATTT6660               CTTTAGTATATCTATTACGACTACGATAGTTATATAGATATCCGCCTTGTAAAATACGAG6720               ATTGAACCTTTGCGTCTGCTATATTGAGCATCGTTTCATATTCGTTTTTATCTGGAATAA6780               TAATATTACAATGTCGTTTCATATCACCTTTACACATCAATTGCATATTTCCCGGGACAT6840               TACCATTACAGTGTTCTTGCCATACCAAAACATCACTACCTTTTGATGGCAAATTATATA6900               ACACTGAAAATGGTAGGGCTAGTGAGTTAATAACGAAATGATGTTCCGTAATTTCAAGTT6960               GCTTGATAAAAAATAATACGAATGCGAGCTTTGAAGGGAAAAAGTAAGACTTCCCTTGCC7020               AATCCAATATGACATCAGATGTTACAAAATTTTCATAAATCACTTCTTTACCTTCTGCTG7080               TCATATATTTCTTCAAGATCGCTTTACGATTTAAATCGTAACAGTTTGTGCAATTTAATA7140               CCATTCTTAGAATAATAATCGACAAATCGGACACGTTGTTGGTCATCAAACCATTCGACA7200               CGACTAACAATTCTAGGGCGCTCTCCACTTTGATAAAATATTTTGCCTCGTAGACGTCCC7260               ATATCATTAATTGTAGCCGAATTGTTGTTACCTTTAATTTCCCAAAAAGCTGGTACAGTA7320               ACCTGATTAAAAAATCGTGGTTTCATATTTTCTGTATTATGATTATCTGCAAAAAATTGA7380               TACGGTGATATAACATCGTCCGGTAAAAAGCCATTGTCATTGAGTACAATTGTTAAATCT7440               TCTTCCAACTTACTGGCTTTAAAAGACTCATATAACTTTCGTGAATGATCGTTAAAGTAA7500               TCAAATAATTTAATCATGTAGCACCTCTTGAACTAATGTTTCCCATTTTAAAATAATATC7560               TTGAGTCATAAATTGCTGTGCCACTTCATAAGAGATGTCATGTGGTGCCTGGGGACCATT7620               GTTAAAATACATTACAATGGCATGAGCTAGTTTTGCGATAACATCATCCACACTATCTTC7680               GTCGGTATCAAAAGGTACCAAGTAGCCATTTTCCCCATCTCGAATAAAGGTTGGGTTACC7740               ATAATTCACATTTAATCCAATCATACCTAGTCCTGAGCCTACCGCTTCCATTAGTGTTAA7800               CCCAAAACCTTCGCTAGTTGATGCAGAAAGAAATAACTCATAATCATTATAAATTTCATC7860               AAGTTTAACATGCCCTTAGTAAACCGAATATAATCTTGTGCGCGGTGTGTATCAATAATT7920               TTACGCAGTCGCGTCTTCTCGCTACCTTCTCCATAAATATCAAATGTTAATTCTGGCACT7980               TGTCGTTTAGCCACGATAACCGCCTTGACAAGCCAATCAATATGTTTCTCATTTGCTAAA8040               CGAGATGCACTAATCATCGCATATGGCTTTCTTGATAATTTAGGATATGATAACGCATCA8100               ATGCTTCCCACCGGDATAGTATAGACACGTGGACGATAACCTTGATATTGCTCAAATTGT8160               CGACAAACCATATGATTTTGAATATCTGTTGCTGTAATAAAGAAATCAATGTATTTAGCT8220               TTTGAAAATTGATATTCATAATAATTGTTCCATAGTATATGCTGCTCGCTCATCATATTA8280               TTACTATAATGATCAGCATGAATCACAACACCAACTTTACTATCACCTTTATGCTGCAAA8340               ACAGCCTGACCAATATCAGAAGCGCGGTCTAATATGACAATATCGTCTCGGGTTAAATTC8400               AATCGTTGTAAAAAGTATGCAATAAATTCCGTTTTGTTATACAACACCGCATCTTCAAAC8460               ACATATATAGAGCTGTCTCCATCAATATATTCGTTATAAGCGATGGAACCATCTTCATTA8520               TAGAATTGTCGCATATATAATTTCGCTTTATTATCAGCTGGTGCATAATACTCAGAAAAT8580               ATACGCGTATAACTATAAAAATCTTTACGTACTAACATACTATTAATTACAATTCTGCAC8640               GATCCACAACATCTTTTTGTTCATTTTGTAGATAACATGTTACAAATGATGATTTCCCAT8700               TAAAATATAGACGGACTATCTTACCATTTCTTTCTCTAAAACTAATTTCATGACCAAGCT8760               CACGTTCAATGTCATCTAACGTGTACGTTGTTGGTGCTATAGAAATATCACTAAAAATAC8820               TGATACAACCAAATAACTTCTTGATCTTTAAACCCAATGTTTTGCGTTAATGTCTGTATG8880               TTCTCTGACTGTATAAAATCTAAAAACACAAATTTAGTGTCTTGATTTGTACGTCTCAAT8940               AATTTAGCACGGTAAGCTT8959                                                        (2) INFORMATION FOR SEQ ID NO:2:                                               (i) SEQUENCE CHARACTERISTICS:                                                  (A) LENGTH: 10207 base pairs                                                   (B) TYPE: nucleic acid                                                         (C) STRANDEDNESS: double                                                       (D) TOPOLOGY: linear                                                           (ii) MOLECULE TYPE:Genomic DNA                                                 (vi) ORIGINAL SOURCE:                                                          (A) ORGANISM: Staphylococcus aureus                                            (B) STRAIN: Clinical Isolate SA- 24                                            (xi) SEQUENCE DESCRIPTION: SEQ ID NO:2:                                        AAGCTTATGGACCTATTTTAGGTATATTGATTAGTTGGCTTGGATTAATTTCTGGAACAT60                 TTACAGTCTATTTGATCTGTAAACGATTGGTGAACACTGAGAGGATGCAGCGAATTAAAC120                AACGTACTGCTGTTCAACGCTTGATTAGTTTTATTGATCGCCAAGGATTAATCCCATTGT180                TTATTTTACTTTGTTTTCCTTTTACGCCAAATACATTAATAAATTTTGTAGCGAGTCTAT240                CTCATATTAGACCTAAATATTATTTCATTGTTTTGGCATCATCAAAGTTAGTTTCAACAA300                TTATTTTAGGTTATTTAGGTAAGGAAATTACTACAATTTTAACGCATCCTTTAAGAGGGA360                TATTAATGTTAGTTGTGTTGGTTGTATTTTGGATTGTTGGAAAAAAGTTAGAACAGCATT420                TTATGGGATCGAAAAAGGAGTGACATCGTGAAAAAAGTTGTAAAATATTTGATTTCATTG480                ATACTTGCTATTATCATTGTACTGTTCGTACAAACTTTTGTAATAGTTGGTCATGTCATT540                CCGAATAATGATATGTCACCAACCCTTAACAAAGGGACGTGTTATTGTAAATAAAATTAA600                AGTTACATTTAATCAATTGAATAATGGTGATATCATTACATATAGGCGTGGTAACGAGAT660                ATATACTAGTCGAATTATTGCCAAACCTGGTCAATCAATGGCGTTTCGTCAGGGACAATT720                ATACCGTGATGACCGACCGGTTGACGCATCTTATGCCAAGAACAGAAAAATTAAAGATTT780                TAGTTTGCGCAATTTTAAAGAATTAGATGGAGATATTATACCGCCTAACAATTTTGTTGT840                GCTAAATGATCATGATAACAATCAGCATGATTCTAGACAATTTGGTTTAATTGATAAAAA900                GGATATTATTGGTAATATAAGTTTGAGATATTATCCTTTTTCAAAATGGACGATTCAGTT960                CAAATCTTAAAAAGAGGTGTCAAAATTGAAAAAAGAATTATTGGAATGGATTATTTCAAT1020               TGCAGTCGCTTTTGTCATTTTATTTATAGTAGGTAAATTTATTGTTACACCATATACAAT1080               TAAAGGTGAATCAATGGATCCAACTTTGAAAGATGGCGAGCGAGTAGCTGTAAACATTAT1140               TGGATATAAAACAGGTGGTTTGGAAAAAGGTAATGTAGTTGTCTTCCATGCAAACAAAAA1200               TGATGACTATGTTAAACGTGTCATCGGTGTTCCTGGTGATAAAGTAGAATATAAAAATGA1260               TACATTATATGTCAATGGTAAAAAACAAGATGAACCATATTTAAACTATAATTTAAAACA1320               TAAACAAGGTGATTACATTACTGGGACTTTCCAAGTTAAAGATTTACCGAATGCGAATCC1380               TAAATCAAATGTCATTCCAAAAGGTAAATATTTAGTTCTTGGAGATAATCGTGAAGTAAG1440               TAAAGATAGCCGTGCGTTTGGCCTCATTGATGAAGACCAAATTGTTGGTAAAGTTTCATT1500               TAGATTCTGGCCATTTAGTGAATTTAAACATAATTTCAATCCTGAAAATACTAAAAATTA1560               ATATGAAACAAATACAACATCGTTTGTCGGTTTTAATACTGATAAACGATGTTTTATTTT1620               GTTAGTACCACAATAAAAGCTAAGTTCGAAATGAACTTATAATAAATCAATCACAATCAC1680               TTTGTGTTAAAATATGTGTCAAAGGAAGTGAGGGTTTGTCATGACATTACATGCTTATTT1740               AGGTAGAGCGGGAACAGGTAAGTCTACGAAAATGTTGACCGAAATAAAACAAAAAATGAA1800               AGCAGATCCGCTTGGAGATCCAATCATTTTAATTGCGCCAACTCAAAGTACATTTCAATT1860               AGAACAAGCCTTTGTCAATGATCCGGAATTAAATGGTAGTTTAAGAACAGAAGTGTTGCA1920               TTTTGAACGATTAAGTCATCGTATTTTCCAAGAAGTTGGTAGTTATAGCGAACAAAAGTT1980               ATCTAAAGCTGCAACGGAAATGATGATTTATAACATTGTTCAAGAACAACAAAAGTATTT2040               AAAACTTTATCAATCACAAGCAAAATATTATGGGTTTAGTGAAAAATTAACAGAACAAAT2100               TCAAGATTTTAAAAAATATGCAGTAACGCCTGAACATTTAGAACACTTTATTGCTGATAA2160               AAATATGCAAACTCGAACTAAAAATAAGTTAGAGGATATTGCTTTAATATACCGTGAGTT2220               CGAACAACGCATTCAAAACGAGTTTATTACTGGTGAGGATTCATTACAATATTTTATTGA2280               TTGTATGCCGAAATCAGAGTGGCTAAAACGTGCTGATATATATATTGATGGTTTTCACAA2340               CTTTTCAACGATTGAGTATTTAATAATCAAAGGATTAATTAAATATGCGAGAGTGTCACA2400               ATTATATTGACGACAGATGGTAACCACGATCAATTTAGTTTTTTAGAAAACCATCGGAAG2460               TGTTACGACATATTGAAGAAATAGCAAATGAACTCAATATTTCTATTGAACGTCAATATT2520               TCAACCAATTATATCGCTTCAATAATCAAGATTTAAAGCATCTTGAACAAGAATTTGATG2580               TACTTCAAATCAATCGAGTGGCATGTCAAGGTCATATCAATATTTTAGAATCTGCGACTA2640               TGAGAGAGGAAATAAATGAAATTGCGCGACGTATCATCGTTGATATTCGTGATAAGCAAT2700               TACGATATCAAGATATTGCAATTTTATATCGTGACGAGTCTTATGCTTATTTATTTGATT2760               CCATATTACCGCTTTATAATATTCCTTATAACATTGATACAAAGCGTTCGATGACACATC2820               ATCCGGTCATGGAAATGATTCGTTCATTGATTGAAGTTATTCAATCTAATTGGCAAGTGA2880               ATCCAATGCTACGCTTATTGAAGACTGATGTGTTAACGGCATCATATCTAAAAAGTGCAT2940               ACTTAGTTGATTTACTTGAAAATTTTGTACTTGAACGTGGTATATACGGTAAACGTTGGT3000               TAGATGATGAGCTATTTAATGTCGAACATTTTAGCAAAATGGGGCGTAAAGCGCATAAAC3060               TGACCGAAGATGAACGTAACACATTTGAACAAGTCGTTAAGTTAAAGAAAGATGTCATTG3120               ATAAAATTTTACATTTTGAAAAGCAAATGTCACAAGCGGAAACTGTAAAAGACTTTGCAA3180               CTGCTTTTTATGAAAGTATGGAATATTTCGAACTGCCAAATCAATTGATGACAGAGCGAG3240               ATGAACTTGATTTAAATGGTAATCATGAAAAGGCGGAGGAAATTGATCAAATATGGAATG3300               GCTTAATTCAAATCCTTGACGACTTAGTTCTAGTATTTGGAGATGAACCAATGTCGATGG3360               AACGTTTCTTAGAAGTATTTGATATTGGTTTAGAACAATTAGAATTTGTCATGATTCCAC3420               AAACATTAGATCAAGTTAGTATTGGTACGATGGATTTGGCTAAAGTCGACAATAAGCAAC3480               ATGTTTACTTAGTTGGAATGAACGACGGCACCATGCCACAACCAGTAACTGCATCAAGTT3540               TAATTACTGATGAAGAAAAGAAATATTTTGAACAACAAGCAAATGTAGAGTTGAGTCCTA3600               CATCAGATATTTTACAGATGGATGAAGCATTTGTTTGCTATGTTGCTATGACTAGAGCTA3660               AGGGAGATGTTACATTTTCTTACAGTCTAATGGGATCAAGTGGTGATGATAAGGAGATCA3720               GCCCATTTTTAAATCAAATTCAATCATTGTTCAACCAATTGGAAATTACTAACATTCCTC3780               AATACCATGAAGTTAACCCATTGTCACTAATGCAACATGCTAAGCAAACCAAAATTACAT3840               TATTTGAAGCATTGCGTGCTTGGTTAGATGATGAAATTGTGGCTGATAGTTGGTTAGATG3900               CTTATCAAGTAATTAGAGATAGCGATCATTTAAATCAAGGTTTAGATTATTTAATGTCAG3960               CATTAACGTTTGACAATGAAACTGTAAAATTAGGTGAAACGTTGTCTAAAGATTTATATG4020               GTAAGGAAATCAATGCCAGTGTATCTCGTTTTGAAGGTTATCAACAATGCCCATTTAAAC4080               ACTATGCTTCACATGGTCTGAAACTAAATGAACGAACGAAATATGAACTTCAAAACTTTG4140               ATTTAGGTGATATTTTCCATTCCGTTTTAAAATATATATCTGAACGTATTAATGGCGATT4200               TTAAACAATTAGACCTGAAAAAAATAAGACAATTAACGAATGAAGCATTGGAAGAAATTT4260               TACCTAAAGTTCAGTTTAATTTATTAAATTCTTCAGCTTACTATCGTTATTTATCAAGAC4320               GCATTGGCGCTATTGTAGAAACAACACTAAGCGCATTAAAATATCAAGGCACGTATTCAA4380               AGTTTATGCCAAAACATTTTGAGACAAGTTTTAGAAGGAAACCAAGAACCAAATGTACGA4440               ATTAATTGCACAAACATTAACGACAACTCAAGGTATTCCAATTAATATTAGAGGGCAAAT4500               TGACCGTATCGATACGTATACAAAGAATGATACAAGTTTTGTTAATATCATTGACTATAA4560               ATCCTCTGAAGGTAGTGCGACACTTGATTTAACGAAAGTATATTATGGTATGCAAATGCA4620               AATGATGACATACATGGATATCGTTTTACAAAATAAACAACGCCTTGGATTAACAGATAT4680               TGTGAAACCAGGTGGATTATTATACTTCCATGTACATGAACCTAGAATTAAATTTAAATC4740               ATGGTCTGATATTGATGAAGATAAACTAGAACAAGATTTAATTAAAAAGTTTAAGCTGAG4800               TGGTTTAGTGAATGCAGACCAAACTGTTATTGATGCATTGGATATTCGTTTAGAACCTAA4860               ATTCACTTCAGATATTGTACCAGTTGGTTTGAATAAAGATGGCTCTTTGAGTAAACGAGG4920               CAGCCAAGTGGCAGATGAAGCAACAATTTATAAATTCATTCAGCATAACAAAGAGAATTT4980               TATAGAAACAGCTTCAAATATTATGGATGGACATACTGAAGTGCACCATTAAAGTACAAA5040               CAAAAATTGCCATGTGCTTTTTGTAGTTATCAATCGGTATGTCATGTAGATGGCATGATT5100               GATAGTAAGCGATATCGAACTGTAGATGAAACAATAAATCCAATTGAAGCAATTCAAAAT5160               ATTAACATTAATGATGAATTTGGGGGTGAGTAATAGATGACAATTCCAGAGAAACCACAA5220               GGCGTGATTTGGACTGACGCGCAATGGCAAAGTATTTACGCAACTGGACAAGATGTACTT5280               GTTGCAGCCGCGGCAGGTTCAGGTAAAACAGCTGTACTAGTTGAGCGTATTATCCAAAAG5340               ATTTTACGTGATGGCATTGATGTCGATCGACTTTTAGTCGTAACGTTTACAAACTTAAGC5400               GCACGTGAAATGAAGCATCGTGTAGACCAACGTATTCAAGAGGCATCGATTGCTGATCCT5460               GCAAATGCACACTTGAAAAACCAACGCATCAAAATTCATCAAGCACAAATATCTACACTT5520               CATAGTTTTTGCTTGAAATTAATTCAACAGCATTATGATGTATTAAATATTGACCCGAAC5580               TTTAGAACAAGCAGTGAAGCTGAAAATATTTTATTATTAGAACAAACGATAGATGAGGTC5640               ATAGAACAACATTACGATATCCTTGATCCTGCTTTTATTGAATTAACAGAACAATTGTCT5700               TCAGATAGAAGTGATGATCAGTTTCGAATGATTATTAAACAATTGTATTTCTTTAGCGTT5760               GCAAATCCAAATCCTACAAATTGGTTGGATCAATTGGTGACACCATACGAAGAAGAAGCA5820               CAACAAGCGCAACTTATTCAACTACTAACAGACTTATCTAAAGTATTTATCACAGCTGCC5880               TATGATGCTTTAAATAAGGCGTATGATTTGTTTAGTATGATGGATGGCGTCGATAAACAT5940               TTAGCTGTTATAGAAGATGAACGACGTTTAATGGGGCGTGTTTTAGAAGGTGGTTTTATT6000               GATATACCTTATTTAACTGATCACGAATTTGGCGCGCGTTTGCCTAATGTAACAGCGAAA6060               ATTAAAGAAGCAAATGAAATGATGGTCGATGCCTTAGAAGATGCTAAACTTCAGTATAAA6120               AAATATAAATCATTAATTGATAAAGTGAAAAATGATTACTTTTCAAGAGAAGCTGATGAT6180               TTGAAAGCTGATATGCAACAATTGGCGCCACGAGTAAAGTACCTTGCGCGTATTGTGAAA6240               GATGTTATGTCAGAATTCAATCGAAAAAAGCGTAGCAAAAATATTCTGGATTTTTCTGAT6300               TATGAACAATTTGCATTACAAATTTTAACTAATGAGGATGGTTCGCCTTCAGAAATTGCC6360               GAATCATACCGTCAACACTTTCAAGAAATATTGGTCGATGAGTATCAAGATACGAACCGG6420               GTTCAAGAGAAAATACTATCTTGCATCAAAACGGGTGATGAACATAATGGTAATTTATTT6480               ATGGTTGGAGATGTTAAGCAATCCATTTATAAATTTAGACAAGCTGATCCAAGTTTATTT6540               ATTGAAAAGTATCAACGCTTTACTATAGATGGAGATGGCACTGGACGTCGAATTGATTTG6600               TCGCAAAACTCCGTTCTCGAAAAGAAGTACTGTCAACGACTAACTATATATCAAACATAT6660               GATGGATGAACAAGTCGGTGAAGTAAAATATGATGAAGCGGCACAGTTGTATTATGGTGC6720               ACCATATGATGAATCGGACCATCCAGTAAACTTAAAAGTGCTTGTTGAAGCGGATCAAGA6780               ACATAGTGATTTAACTGGTAGTGAACAAGAAGCGCATTTTATAGTAGAACAAGTTAAAGA6840               TATCTTAGAACATCAAAAAGTTTATGATATGAAAACAGGAAGCTATAGAAGTGCGACATA6900               CAAAGATATCGTTATTCTAGAACGCAGCTTTGGACAAGCTCGCAATTTACAACAAGCCTT6960               TAAAAATGAAGATATTCCATTCCATGTGAATAGTCGTGAAGGTTACTTTGAACAAACAGA7020               AGTCCGCTTAGTATTATCATTTTTAAGAGCGATAGATAATCCATTACAAGATATTTATTT7080               AGTTGGGTTAATGCGCTCCGTTATATATCAGTTCAAAGAAGACGAATTAGCTCAAATTAG7140               AATATTGAGTCAAATGATGACTACTTCTATCAATCGATTGTAAATTACATTAATGACGAA7200               GCAGCAGATGCTATTTTAGTTGATAAATTAAAAATGTTTTTATCAGATATTCAAAGTTAC7260               CAACAATATAGTAAAGATCATCCGGTGTATCAGTTAATTGATAAATTTTATAATGATCAT7320               TATGTTATTCAATACTTTAGTGGACTTATTGGTGGACGTGGACGACGTGCAAACCTTTAT7380               GGTTTATTTAATAAAGCTATCGAGTTTGAGAATTCAAGTTTTAGAGGTTTATATCAATTT7440               ATTCGTTTTATCGATGAATTGATTGAAAGAGGCAAAGATTTTGGTGAGGAAAATGTAGTT7500               GGTCCAAACGATAATGTTGTTAGAATGATGACAATTCATAGTAGTAAAGGTCTAGAGTTT7560               CCATTTGTCATTTATTCTGGATTGTCAAAAGATTTTAATAAACGTGATTTGAAACAACCA7620               GTTATTTTAAATCAGCAATTTGGTCTCGGAATGGATTATTTTGATGTGGATAAAGAAATG7680               GCATTTCCATCTTTAGCTTCGGTTGCATATAAAGCTGTTGCCGAAAAAGAACTTGTGTCA7740               GAAGAAATGCGATTAGTCTATGTAGCATTAACAAGAGCGAAAGAACAACTTTATTTAATT7800               GGTAGAGTGAAAAATTGATAAATCGTTACTAGAACTAGAGCAATTGTCTATTTCTGGTGA7860               GCACATTGCTGTCAATGAACGATTAACTTCACCAAATCCGTTCCATCTTATTTATAGTAT7920               TTTATCTAAACATCAATCTGCGTCAATTCCAGATGATTTAAAATTTGAAAAAGATATAGC7980               ACAAGTTGAAGATAGTAGTCGTCCGAATGTAAATATTTCAATTATATACTTTGAAGATGT8040               GTCTACAGAAACCATTTTAGATAATAATGAATATCGTTCGGTTAATCAATTAGAAACTAT8100               GCAAAATGGTAATGAGGATGTTAAAGCACAAATTAAACACCAACTTGATTATCAATATCC8160               ATATGTAAATGATACTAAAAAGCCATCCAAAACAATCTGTTTCTGAATTGAAAAGGCAAT8220               ATGAAAGAAGAAAGTGGCACAAGTTACGAACGAGTAAGACAATATCGTATCGGTTTTCAA8280               CGTATGAACGACCTAAATTTCTAAGTGAACAAGGTAAACGAAAAAGCGAATTGAAATTGG8340               TACGTTAATGCATACAGTGATGCAACATTTACCATTCAAAAAAGAACGCATATCTGAAGT8400               TGAGTTACATCAGTATATCGATGGATTAATCGATAAACATATTATCGAAGCAGATGCGAA8460               AAAAGATATCCGTATGGATGAAATAATGACATTATCAATAGTGAGTATATTCGATTATTG8520               CTGAAGCAGAGCAAGTTTATCGTGAATTACCGTTTGTAGTTAACCAAGCATTAGTTGACC8580               AATTGCCACAAGGAGACGAAGACGTCTCAATTATTCAAGGTATGATTGACTTAATCTTTG8640               TTAAAGATGGTGTGCATTATTTTGTAGACTATAAAACCGATGCATTTAATCGTCGCCGTG8700               GGATGACAGATGAAGAAATTGGTACACAATTAAAAAATAAATATAAGATACAGATGAAAT8760               ATTATCAAAATACGCTTCAAACGATACTTAATAAAGAAGTTAAAGGTTATTTATACTTCT8820               TCAAATTTGGTACATTGCAACTGTAGTATTTTGATTTTCAAAAGAATAAAAAATAATTTC8880               GATTAAGTGCAAAGTCCTTGTAGCAGAATGAACACAACTCATTTTCAAAATTGTCTTACT8940               TATTTATTTGTTATTTGATAACGAAAAAAGTTATAATGTGAATTAAGATAAAGATGAGGA9000               GTTGAGAATGAATGAAATTCTTATCATTCAAGTATAATGACAAAACTTCATATGGCGTTA9060               AAGTAAAACGCGAAGATGCTGTATGGGATTTAACACAAGTATTTGCTGACTTTGCAGAAG9120               GAGATTTCCATCCTAAAACATTGTTAGCTGGTTTACAACAAAATCATACTTTAGATTTTC9180               AAGAACAAGTACGTAAAGCAGTTGTAGCAGCAGAAGATAGCGGCAAAGCTGAAGACTATA9240               AAATTTCATTTAATGACATTGAATTCTTACCACCAGTAACACCTCCGAATAATGTGATTG9300               CTTTTGGTAGAAATTACAAAGATCATGCGAACGAATTAAATCATGAAGTAGAAAAATTAT9360               ATGTATTTACAAAAGCAGCGTCATCTTTAACAGGAGATAATGCAACAATTCCAAATCATA9420               AAGATATTACTGATCAATTAGATTATGAAGGTGAATTAGGTATTGTTATTGGTAAGTCTG9480               GTGAAAAGATTCCAAAAGCATTAGCTTTAGATTATGTTTACGGCTATACAATTATTAACG9540               ATATCACTGATCGCAAAGCACAAAGTGAACAAGATCAAGCATTTTTATCAAAAAGTTTAA9600               CTGGCGGTTGCCCAATGGGTCCTTATATCGTTACTAAAGACGAACTACCATTACCTGAAA9660               ATGTAAATATTGTTACAAAAGTTAACAATGAAATTAGACAAGATGGTAACACTGGCGAAA9720               TGATTCTTAAAATTGATGAATTAATAGAAGAAATTTCAAAATATGTTGCACTACTACCGG9780               GAGATTATTATTGCAACTGGTACACCAGCTGGCGTTGGTGCAGGTATGCAACCACCTAAA9840               TTTTTACAACCAGGTGATGAAGTTAAAGTGACTATTGATAATATTGGAACGCTGACAACT9900               TATATCGCTAAATAATTATCATTTAAAAAGCTAACCAGGTCTTTATATAGATTGGTTAGT9960               TTTTTCTTGCTTTTCTAAAAAGGTGTTAAAGATAAATTATTTATAATGTTACCATTTTGA10020              GATGAAAGTGAAATATTGATATTAAGAAGTAGTTGATTATTTTACAGCAGATTCACAATA10080              TTCTAATAAGGGCAATGCAAATGTCATGTTCTTCCTCTCAAATATAGAAGTGTGGTAGAA10140              TATATATTCGTGTATAATCAAATCTAGATTAAATTACAAGCAAGTGGGTATTAATCCCAA10200              GAAGCTT10207                                                                   (2) INFORMATION FOR SEQ ID NO:3:                                               (i) SEQUENCE CHARACTERISTICS:                                                  (A) LENGTH: 2082 base pairs                                                    (B) TYPE: nucleic acid                                                         (C) STRANDEDNESS: double                                                       (D) TOPOLOGY: linear                                                           (ii) MOLECULE TYPE: Genomic DNA                                                (vi) ORIGINAL SOURCE:                                                          (A) ORGANISM: Staphylococcus aureus                                            (B) STRAIN: Clinical Isolate SA- 36                                            (xi) SEQUENCE DESCRIPTION: SEQ ID NO:3:                                        AAGCTTTCTAATCTATCGTTAATGATTTGCTTTAAAATTGGGTCGAAGTTAATTGAAGGT60                 GTGAAGTGTATATCTGTATTAATAACCATGTCATTCATTTGCTGCTTCACTTTGTTAACA120                AGTCTTCCGTCATATAAAAATAATGGTACGACAATCAATTTTTGATACCGTTTCGAGATG180                CTTTCTAAATCATGTGTAAAACTAATCTCTCCATATAGCGTTCTCGCATAAGTAGGTTTA240                TTAATCTGCAAATGTTGAGCGCATATTTGTAACTCTTCGTGTGCCTTAGTAAAATTTCCA300                TTAATATTGCCGTGTGCAACAACCATAACTCCAACTTGTTGTTCGTCACCTGCTAATGCG360                TCACAAATACGTTGTTCAATTAATCGTCTCATTAAAGGATGTGTGCCAAGTGGCTCGCTT420                ACTTCTACCTTTATGTCTGGATACCGTCGTTTCATTTCATGAACGATATTCGGTATATCC480                TTGAGATAATGCATTGCACTAAAGATTAGCAATGGTACAATTTTAAAATGGTCAACCCCA540                CTTTGAATCAACGTCGTCATTACCGTCTCTAAATCCTGATGCTCACTTTCTAAAAACGCA600                ATATCATAGTGATGTATATCATCTTTTACTAATTCAGAAATAAATGCTTCTAACGCTTGA660                TTCTGTCGTCCGTGCCTCATGCCATGTGCAACAATGATATTCCCATTCACATTTACCAAC720                CCTTTCACACGTATTGTATACCAAATCATTTTGTTTTTGTGAAAAGAATCACATTATAAT780                GTAAAATCAGGGAATTCCCTGATGCCTGTAGTCATGCATATTCCTTATACATTTTCCCTT840                TTTGTTAAATCAAAAAAAGCGACCGATATATGAATCCCTACTCAACATTTATTTGAGCAA900                GCATCAATATATCGGTCGCTTGTAGTGTATATTATTATCTTAAAATGGTGGTTGGCCTAA960                TATTGTTTCGTCAAAGCGCTCGGGTATCAATACTTTGCGCATGATCACACCTAAATCGCC1020               ATCATCATTTTCATGTTCGCTGTATATTTCATAACCTCTTTTTTCATAAATTTTAAGTAA1080               CCACGGATGCAATCTTGCAGATGTACCTAAAGTAACTGCCGCTGACTTTAACGTATCTCG1140               CAAAAATGCTCTTCAACATAAGTAAGTAATTGGCTACCATAGCCTTTCCCTTCATACTCA1200               GGATTTGTCGCAAACCACCAGACAAAAGGATAGCCCGAAATACTTTTCACACTTCCCCAA1260               GGATATCTAACCGTAATCGTAGATATAATTTCATCATCAATTGTCATGACAAATGTAGTA1320               TTTTTATCTATATTTTCTTTAACAGCATCTAAATTAGCATTAACTGAAGGCCAATCAATA1380               CCTAGTTCTCTTAGAGGCGTAAATGCTTCATGCATGAGTTGTTGCAATTTTTCTGCATCT1440               TGTTCACTTGCGAGTCGAATCATCGTTTTTGTCATATTAATCCCCACTCTTTTTTAAATG1500               ATTTAACCATATTTTATTTTTAAAATAAATATCCATCAAAGTGTATCAATAAATTTATCA1560               CATGTCAGAAAGTATGCTTCATCTGAATACACCAATACTCTCATGAAACTTATTAAAAAT1620               TACTCTCTCAACGTAAAAAAACCATTCAAATTCATGAATGGTTTGGAAGAATGATTCATT1680               GTTACGCTATTTAATCACTACATCTTAATTATTGTTGCTCTAAACGATTACGCTTACCAT1740               TTAAGAAAGCATAAACGAGACCTACAAAAATACCGCCACCGACAAAGTTACCTAAGAAAG1800               CAAAAACGATATTTTTTAAAACATGTAACCATGAAACTGCATCAAGGTTAAAGAATACCA1860               TACCTGCATATAGACCTGCATTGAACACAACGTGCTCATATCCCATGTATACAAAGACCA1920               CGACACCACAAGCTATGAAGAATGCCTTTGTTAAGCCGCCTTTGAATTGCATAGAGATGA1980               AAATACCAATATTAATAAAGAAGTTACAGAAAATACCTTTTGTAAAAATATTCAACCATG2040               TTGAATCAACAGTCTTTTTCTGAACTAAAGCTGTTAAAGCTT2082                                 (2) INFORMATION FOR SEQ ID NO:4:                                               (i) SEQUENCE CHARACTERISTICS:                                                  (A) LENGTH: 2885 base pairs                                                    (B) TYPE: nucleic acid                                                         (C) STRANDEDNESS: double                                                       (D) TOPOLOGY: linear                                                           (ii) MOLECULE TYPE: Genomic DNA                                                (vi) ORIGINAL SOURCE:                                                          (A) ORGANISM: Staphylococcus aureus                                            (B) STRAIN: Clinical Isolate SA- 77                                            (xi) SEQUENCE DESCRIPTION: SEQ ID NO:4:                                        AAGCTTTTGATTAATTTGGGCTTTAAAGTATTCCCAATTATAATTCTTCATGATTTTCTT60                 ATTGGATTTCGAATTTGGTTTCATGCATTGTTGCCTCAAAGAACATGCTGAACAGTCATC120                GCATTCATATAGCTTGAAGTCACGTTTAAAACCATATCTATCATTACGGTATGCATATCT180                TTTAAAACCTATTCTTTTGTTATTAGGACATATAAATTCATCATTAAGTTCGTCATATTT240                CCAATTTTGAGTGTTAAAAATGTCACTTTTAAACTTTCTAGTTTTATCTTTAATAAACAT300                GCCATACGTAATAAGTGGCGTTTTATTAAAACATCTATAATAGCCATATAGTTTTGCTCA360                CTATCATAACTGCATCAGCTACATTAACTCTGGTAATACCGAGGATTTGAATCATTGTTA420                AAAATGGAATTAAAGTTCTAGTATCTGTTGGGGTTTGAAATAGGTCATAGGATAAAAAAA480                TTGAGAATTTGTCGCTATTTGTAAATTGTATCCTGGCTTAAGTTGGCCATTTTTCATATG540                GTCTTCCTTCATTCTCATAAAAGTTGCATCATGATCAGCCCAGAAAGCTATTTCTATCTT600                TAAGAATCCATTTTTGTTCTTCATATTTATTTTTTCTTTCGGAATAATCATCAAATTTCT660                TTTTGAACTTCTTAATCTCAGTTCTTTTTTACGGGTCTGTTTTCTAATTTGAGCACTCTT720                CGTTCTAAATAGAATGATTTAAATCTTCGATTTCTTTTATCTAAATGACTACCAATTAAA780                TCTATTTCTTCTCGTGATTTTGAATACTTTTCTTCCACACAAATGTATATCTATTGGCAT840                TAGCTTCTACTTATGTACCATCAATAAAAATTGAATTATTATCAATAAGATTTTGCTTTA900                AACATTGACTATGGAACTGAATAAATAAAGATTCAATTAACGCATCAGTATTAGGATTCA960                CTCTAAAACGATTAATAGTTTTATAAGAAGGTGTTTGATCTTGAGCTAACCACATCATTC1020               GAATACTGTCATGAAGTAATTTCTCTATTCTACGACCAGAAAATACAGATTGAGTATATG1080               CATATAAGATGATTTTTAACATCATTTTTGGATGATAGGATGTTGCGCCACGATGATGTC1140               TGAATTCATCGAATTCGCTATCAGGTATCGTTTCAACAATTTCATTTACATATCGCGAAA1200               TATCATTTTAAGGAATTCTAACAGAAGTTTCTATTGGTAGTGTAAGTTGGGCAAAGTGTC1260               TTATTTTTTTAAAGTATGTAAAAGTAAAATTACATGTTAATACGTAGTATTAATGGCGAG1320               ACTCCTGAGGGAGCAGTGCCAGTCGAAGACCGAGGCTGAGACGGCACCCTAGGAAAGCGA1380               AGCATTCAATACGAAGTATTGTATAAATAGAGAACAGCAGTAAGATATTTTCTAATTGAA1440               AATTATCTTACTGCTGTTTTTTTAGGGATTTATGTCCCAGCCTGTTTTATTTTCGACTAG1500               TTTGGAGAATTTATTGACATTCACATTATTTAAACGGCAACAAAGATTGTTTTATTTTGA1560               TAGGCATTATATGGTGTTAAAAAATTTGCATGAAAATTAAAAAATGCTTCGTTCAGGAAG1620               GTGTCGTAATTTACCTATTTGCTGAATGAAGCATTTTATTTTTAAATATGATAGCCAATA1680               TAACAAGCTATAAATCCAATGATGAATTGTAAAAGTGAATAATTGAGAAAAAGGTTAATA1740               TCAAATTTTGGTGTCATCATTAATGTAAGTTCCTTGGCTAACGTTGAGAAAGTTGTTAAG1800               CCACCTAAAAAAACCGGTGACAAAGAACGCAGGGAACCATGAGATTGAAATTGATAGGCC1860               TATAGTTAATCCAATTAAAAAACTACCAACTAGATTTACTATCAATGTTGCGATAGGTAA1920               CTTTGAAGTAAATTTATGATTAAAATAATCAGTAATGGCACTTCTAGCAATTGCGCCAAA1980               ACCGCCGCCAATCATGACTAAAATGATTGATATCATGATAAACCACCACCTAGTTTTATA2040               CCGACGTAACATAACAAAATACCAAAGACATAACTTGTTACAGCATATAGTAGTAAAGTT2100               ATAAATTGTTGATGATCAAACATATGTATTAATTCTAATTGAAATGTTGAAAAAGTCGTT2160               AAAGCACCAAGAAAACCAGTCGTAATAGCTTTTTTTAGGGTCGGATGGTTTGAAAAAAAT2220               GCAATTGTTAAGGCTGTTAGCAATCCCATTACAAAGGCACCAGTCAAATTGGCTATCAGT2280               GTTCCGATTGGAAAACCTCCGTCAGTATTCAGAAAAGAAATGAGGTAACGTAATAAAGCG2340               CCTAAAGCACCACCGATAAAAATATATACATATTGCATTTGGTTCACCTCGAAAAGAAGT2400               AGTTTGAATTTAAAAAAGAGGTTTTGGCAACACGACGACAAAAATTGTCGATGCATTATC2460               AAACCTCATTATATGTTATATCTTGTTGTATAACTATAGCGATTAGATGCATAGTTATGA2520               TTTCGAAAATCTAATATTTTTTATACGCAACAACGTCATCAAATTGTTTTACTCATTATA2580               GCATGATACATTGTATTGTTTTGTATTAACGCTACATTGACATTTTATCTTTTTTAAATA2640               AAACCGAATGTACGACAATTGAAAAGATATGTACTAAAATAACAATTAGAATAATCCAAG2700               GCAAACTTTTACTCGCAATTCTAATCCAATCTGCATCAGGCTTTAGTGATTTAATTGAAC2760               GATCTGCAAAAATTATAGACAAAATTAGTACAATTGAGTTAATAACACTGCAGAAAAGTA2820               TTAATTTAATAAAAGAATTAAAAAATCCACTTAGGAAAACGTTATTTGTATTAAAGAAAA2880               AGCTT2885                                                                      (2) INFORMATION FOR SEQ ID NO:5:                                               (i) SEQUENCE CHARACTERISTICS:                                                  (A) LENGTH: 2362 base pairs                                                    (B) TYPE: nucleic acid                                                         (C) STRANDEDNESS: double                                                       (D) TOPOLOGY: linear                                                           (ii) MOLECULE TYPE: Genomic DNA                                                (vi) ORIGINAL SOURCE:                                                          (A) ORGANISM: Staphylococcus epidermidis                                       (B) STRAIN: Clinical Isolate SE- 3                                             (xi) SEQUENCE DESCRIPTION: SEQ ID NO:5:                                        AAGCTTCACAACTTGAAAATATAGCACAAACATTAAAGGATTTAGGTAGAAAACGAGCAA60                 TTTTAATTCATGGTGCAAATGGGATGGATGAGGCCACGCTTTCTGGTGAAAATATCATTT120                ATGAAGTTAGCAGCGAAAGAGCATTAAAAAAATATAGTTTAAAAGCAGAAGAAGTCGGTT180                TAGCTTATGCAAATAATGACACGTTGATAGGTGGTTCACCTCAAACAAATAAACAAATTG240                CATTGAATATCCTAAGTGGCACGGATCACTCAAGTAAACGAGATGTAGTTTTGTTAAATG300                CTGGAATTGCTTTATATGTTGCTGAGCAAGTGGAAAGTATCAAACATGGCGTAGAGAGAG360                CGAAATATCTCATTGATACAGGTATGGCAATGAAACAATATTTAAAAATGGGAGGTTAAG420                TAATGACTATTTTAAATGAAATTATTGAGTATAAAAAAACTTTGCTTGAGCGTAAATACT480                ATGATAAAAAACTTGAAATTTTACAAGATAACGGAAATGTTAAGAGGAGAAAGCTGATTG540                ATTCACTTTAACTATGATAGAACATTATCAGTTATTGCTGAAATAAAATCGAAAAGCCCA600                TCTGTACCTCAATTACCGCAACGTGATCTTGTTCAACAAGTTAAAGATTATCAAAAATAT660                GGTGCTAATGCTATTTCAATATTAACTGATGAAAAATACTTTGGCGGTAGTTTTGAACGA720                TTAAATCAGTTATCAAAGATAACATCGTTACCAGTTTTATGTAAAGATTTTATTATTGAT780                AAAATTCAAATAGATGTTGCAAAACGAGCTGGTGCATCTATTATTTTATTAATAGTAAAT840                ATTTTAAGTGATGACCAATTAAAAGAATTGTATTCATATGCAACAAACCATAATTTAGAA900                GCTCTAGTAGAAGTTCATACAATTAGAGAACTTGAACGTGCACACCAAATTAACCCTAAA960                ATTATTGGTGTTAATAATCGTGATTTAAAACGATTTGAAACCGATGTTCTACATACAAAT1020               AAATTACTTAAGTTTAAAAAGTCTAATTGCTGCTACATTTCAGAGAGTGGCATTCATACA1080               AAAGAAGATGTTGAGAAAATAGTAGATTCAAGTATTGACGGTTTACTTGTAGGGGAGGCA1140               TTAATGAAAACAAATGACTTAAGTCAGTTTTTTGCCTAGTTTAAAGTTAAAGAAGAATCT1200               CTATGATAGTTAAATTTTGTGGTTTTAAAACCGAAAGTGATATTAAGAAAATTAAAAAAT1260               TAGAAGTTGATGCAGTAGGGTTTATACATTATCCCGATAGTAAGAGACATGTCTCACTGA1320               AACAATTAAAATATTTGGCTAAAATAGTGCCAGATCATATAGAGAAAGTAGTGTCGTAGT1380               AAATCCTCAAATGTCCACCATAAAGAGAATAATTAATCAAACTGATATTAACACAATCCA1440               ATTACATGGAAATGAAAGCATTCAATTAATTAGAAATATTAAGAAACTTAATTCAAAAAT1500               AAGAATCATAAAAGCAATTCCAGCAACAAGAAATTTAAATAATAACATTCAAAAGTATAA1560               AGATGAGATAGACTATGTTTATTATAGATACACCATCAATCACATACGGAGGGACAGGTC1620               AAAGTTTTGACTGGAAATTATTAAAAAAAATAAAGGCGTTGATTTTCTCATTGCGGTGGT1680               TTGGATTTTGAAAAGATAAAACGATTAGAAATATATTCATTTGGACAATGTGGTTATGAC1740               ATCTCAACTGGCATTGAGTCACATAATGAAAAAGATTTTAATAAGATGACTCGAATATTA1800               AAATTTTTGAAAGGAGACGAATGATTAATGAAAATTCAAACAGAAGTAGATGAATTGGGC1860               TTTTTCGGTGAATATGGTGGCCAATATGTACCTGAAACATTGATGCCAGCTATTATTGAA1920               CTTAAAAAAGCATATGAGGACGCGAAATCAGATACTCACTTCAAGAAAGAATTTAATTAT1980               TATTTAAGTGAATATGTTGGTAGAGAAACGCCTTTAACATTTGCTGAATCATACACAAAA2040               TTGTTAGGTGGTGCCAAAATATATCTTAAAAGAGAAGACTTAAATCACACTGGTGCTCAT2100               AAAATTAATAACGCGATAGGACAGGCACTATTAGCTAAAAGGATGGGGAAAACTAAATTA2160               GTAGCCGAAACAGGTGCTGGTCAACATGGTGTAGCAAGTGCCACCATCGCTGCTTTATTC2220               GATATGGATCTTATTGTTTTCATGGGAAGTGAAGATATCAAACGTCAACAACTTAACGTA2280               TTTAGAATGGAATTGCTAGGAGCTAAAGTAGTGTCTGTGTCAGATGGGCAAGGAACACTA2340               TCAGATGCTGTAAATAAAGCTT2362                                                     (2) INFORMATION FOR SEQ ID NO:6:                                               (i) SEQUENCE CHARACTERISTICS:                                                  (A) LENGTH: 8654 base pairs                                                    (B) TYPE: nucleic acid                                                         (C) STRANDEDNESS: double                                                       (D) TOPOLOGY: linear                                                           (ii) MOLECULE TYPE: Genomic DNA                                                (vi) ORIGINAL SOURCE:                                                          (A) ORGANISM: Staphylococcus epidermidis                                       (B) STRAIN: Clinical Isolate SE- 22                                            (xi) SEQUENCE DESCRIPTION: SEQ ID NO:6:                                        AAGCTTGTTTTATTGCTTAGTTATATTTCCAATAACACTCATTTTATATGTACGTATTGC60                 CAAAAAAAATTATCTATACAGTAATAAGTATGAAATGAGAACTGGAATAATCATTGGTAT120                TATTGCTTTAATTCTAGTAATTATGCAAGGGTTTCACTTTAACTGGGCTATTATTCCTAT180                TTCTATCTATGGTCATCAGTTTGTATTTTTCGCTGGAATTATTTTAAGTCTTGTTGGTAT240                ATTCTTTAAACGTATAGAATTTGTAGGAGTTGGCTTACTATTTTGTCAAAAACATAGATG300                CAATGGTAACTGACCCGGAAATTGCACAGTTTTTCTCTTTAGCAATTTGGATTATACTTG360                TTGTGCTAATCATTTTTTATACGATACGTTTATCTGAACGCACTAAATCATCATCATATA420                CAAAGATTTAAACTCAGAAAATATGCTAGACATATCTTTCTGAGTTTTTTAATTTATTAA480                AATATATCATTTGTTTACCATATAAGTTTGTTTTAGAAAATGAATCACTATTTTAATATA540                CAAATAATTTAATTACACTGAAAATAACCTAAAAGCGTAACACTATTTTAATATGGGTAT600                ATAAATGACTAAAGGGAGGTGCCAAGATGAATAAAATTCAAATTTGTAATCAGATTGAAC660                TTAACTATATTGATGAAGGCGAAGGCATCCCCATCATTTTAATTCATGGATTAGATGGAA720                ACTTGGCAGGATTTAAAGATTTAAAAAATGAACTCAAGAAGCAGTATAGAGTAATTACTT780                ATGATGTCAGAGGTCATGGAAAATCTTCACGAACAGAATCATATGAATTAAAAGATCATG840                TTGAAGATTTAAATGATTTAATGGGAGCATTAAATATCGATTCTGCACATATTTTAGGAC900                ATGATATGGGGGGCATCATTGCGAGTGAATTTACTGAAAAATATCAATATAAAGTGATTA960                CATTGACAATTGTTTCGGCCAAAAGTGAAGACATTGCAAATGGTTTCAACAAATTAATGG1020               TTGATTACCAAGAAGAATTAGCAGGCTTTAATAAATCTGAGGCAATGATTATTTTATTCT1080               CTAAATTATTTAAAGAGAAAGATAAAGCAATGAAATGGGTATCAAAGCCAAAAATTATAC1140               AATAGACCAACTCCGGAAGAAAGTGCAATTGCAGTACGTGCATTGCTTAATATTAAAGAT1200               TTAACTCGTGTTCATCATAATGTGTCCATACCTACTTTAATTGTGAATGGTAAGTATGAC1260               CCACTCATACAAAATAAAAGTCATTATGATATGGATCAATATTATGATCAAGTTACAAAA1320               ATTGTATTTGATAATTCAGGACATGCACCACATATCGAGGAACCAGAAAAATTCCTGAAA1380               CTCTACTTAGATTTTGTTAGTTAAAAAATAAGAACATAAATAAAAACCCTTAAATGATTA1440               TTGTCGGAAAATCATTTGAGGGTTTTGTAGTAGCAGTAAAGTTTGGACTCAGATCACTAT1500               CGTATTAACTTAATAAAAGAGTAAAACAGTCTTATCTTTCATAAGTGAAAGAAATATCTG1560               TTTNACTCCCTAGCCATTATACTTCATTTCATTATTTGCTTCTGTGATACGGTTGTTTAC1620               TCGTTTAAGTAAATCATCGATTTTTTTACGCTGCTTAGAATCTACTAAGATTAAAACAGT1680               TCTTTCATCGTGTTCATTACGTTTTTTATTAAAGTAATTTTCTTGAGATAAATTTTTAAC1740               AGCTTTAACAACTTGAGGTTGTTTATAATTTAAGTGATTGATAATATCTTTAAGATAATA1800               TTCCTCTTCTTTATTCTCACTAATATAAGTTAATACTGCAAATTCTTCAAAGCTGATTGA1860               GAATTCTTTTTTAATTATTCCTTTTAATCTGTCAGCATAAGTGACCATAGCTAATAATTC1920               AAAGCAGTCATTGATTTTTGAAATAGCCATTAATGAAACCTCCCTATTTATATCATATCC1980               ATAAATCTTAAAACCCATCTTTTTAAATTTAAAGATAGTTAATTATATTATTGAATTAAG2040               ATTACTTGGATACTATACCCTAATTTATTAATTTATATCTATTTTTCTTATGAAAATACG2100               AAAGTGTCCGTCATAATATAGTATTAATTTAAATTTAAAGAATATATTTAATGCTATATT2160               ATTTAGTTAATTATAACTAAATAAAATTAAGAAGTAAACAAATAAGTGTTTATAAAACAA2220               ATTATCTTTTAAAGTTTATACTTGAATTAGCAATGTAGCATTTGCTATATTCAAAAAAAT2280               AAGATTGTTTCTAATTTTCCTTAATTTAATAAAAATTATACTAAAAAGAATACTTTTTGG2340               AAAGAATTTTACTAACATTTTTTATATATAAATGTTTATTAATTTAGAAGTAGGATTTTT2400               AACAACTTTTTCATCTATCAATAAGCCTTTAGTTATATTAATATACCCACTTTTTAAACT2460               CTTTTTGTATGTTACTTCTCTTTTTGTAGAATTAAAACATAGCGTTTTTGAACAATAGCT2520               GACGTAGGTAACTCTATGTCATTTGAGGCTAATTTGATTTTAAAGTGTGTTCCAATTTGA2580               TGATTGGGTTGTGTAGAAAGTAAAATGTCGTAATATGAGACGCCATTTTTTATTTTTGAT2640               GGTATATTCGAAATTTCTTTAATTTTACTAGTAAATTGAGTGTTGTCACTAGATGTTACA2700               GAAATATTTTGATTTATTTTTAATAAATTCAACTCAGATTCTGATATATTAGCACGAATA2760               ATACGTTCGTTGCTATTAATTTGCACTATCTTTTCGTTTGGTTTTGAAGGGATAGAATTA2820               ATATATGAAATACTTCCATTAATTGGTGAAAATAAAGTGGATTTAATTGAGGATTTAGTT2880               TGAATCATTTGTAATTTTAGCTGATTAAGGAATGAATAATAATGTAAATCATTTTTAGAA2940               TTTAAAGTTTTGTTGTTACGTTCATTACTAAGTGTATTTTGGAGTTCCTCATATAAATGA3000               TCTTTTTCATAATTGTAATATTCTAACACTGGAGTGTTTTTAGATACTTTGCTATGATTT3060               TTTACTAAAAGTTTTTGGAGTTGTCCTAAAGTGGGAGTGTAGTAGAAAATATAGCTGTTA3120               AGAGGGGCTTGTATACCAGTTGTTGAAAGGAGTAATTTGGGCTTTGCTTTTATAGTTTTT3180               ATATTTTTAATATCTTCTGTTTTAGAAGTTAATTTAGAGAAAGTAATGTAACTAAAACTA3240               CAAGTTGTGAGAATGAAAATGAATAGTAATGAAGAAATAACGATGCGTTGCTTGGTCATG3300               GATGTTCACCTCATAATATTATTGTGAGGTTATTATACACTATTATTTTAAATGAAATAT3360               ATTAATTTTAAATAAGCATTACTTTTGGTTTGTATATTGTTTTATTTCAAAAAATAAAGT3420               AAATCAATTTAATAAATTGAAAAATAGAAGGCTATCTTTAATTTTAAAATATATGATTCT3480               ACATAAATGTTACTATAAGAAGAATCACTCATAAAAACTGCCAACAAAGACAAAATCTTT3540               GTTGGCAGTTCGAAATAGACATTTATTTGTATGAGGAATCTACATTAATATAAGCGGATA3600               ATTTTTATTCAGAATAAGGAATTTAAAATAATCGTAATAAAATAATACCTATAGCTATAC3660               ATAATAATCCACCTAACTTACGTGATGTTATTTTGTTTTTAGGTGAACCCAACAAACCGA3720               AATGATCGATAATAATACCCATAATCATTTGGCCCATCATAGCAATTATAGTAGTTAAAG3780               CTGCTCCTAAGAAAGGCATTAAAATAATATTAGATGTTACGAATGCCATTCCTAGTATCC3840               CTCCAATAAAATAAATAGATTTAATCTTACCTAGTGTTTTATGAGTAGATGATATTTTCA3900               GACTACGATTAAATACTAATGTTAATATAAATAACGCTATTGTACCAACGCTAAATGATA3960               TGAGTGAAGCAAATATGGATGAGTGTGTGTGTTGAGCCAGTGTGCTGTTGATTGTTGTTT4020               GGATTGGCGGACGAAACCAAATACGAATCCAATAAGCAACCAGAATACTATTGGTGTATT4080               CTTATGTCTATTAACAGGATGTCTACGAACATAATTCATAAATATAATTCCAGTAATTAA4140               AAATATAATTCCAACACCTTTAAATAATGTAAAAGATTGTTGATGGGCGCCCAATAATCC4200               AAATGTATCAATGATTACACCCATAATAATTTGCCCTGTAACCGTAATAACAACAGTAAG4260               TGCTGCGCCTAATCTTGGTAATAATAATAAGTTTCCAGTTAAATAGATAACACCTAATAG4320               TCCTCCTAGGACCCAAGTATAGTTAAGTGTTTGCTTAGAAAAGAATTCTGGTGTTAATAC4380               TTGTGGATGAATAATGATATTAAGCACAAGTAAGCATATTGTTCCGACAGCAAAAGATAT4440               GGTTGAAGCATAAAAAGATGAACGGGTAAATTGGCTTAGCCTTGAGTTGATTGAAGTTTG4500               AATAGGAAGTAACATGCCAACAAAAATTCCTAAAAGATATAGAAAAAACAATGATAAAAA4560               CCAACTTTCTCAATTTAATATGATTATCATACCATTCATAATCATGTTTCTAAAATGATT4620               GAGCCATAAGCAAAGTATAGAAATAAGTTGTGAATGTTCCGAGGTGTCATACAGCCGATA4680               CTATTTTGATGAATCATTATAATAAAATGCACATTAAACAAGTTTTAGAATTAAAAAAAG4740               CGAGACATCATTTTGAATTTGATATCTCACTTCATATTAATAAAAGAACAATGTAAATTA4800               AGTTCTTTTTTAGACTTGAACAATTTTAAAAAATTTGTTCTTCGATAAGTCTTTTTTATG4860               ATTTTAGTACTTTAAATAAAGCGTCAAAAATAATGTTTTATGAATTAATTTTTATCTTCA4920               AATATAACAGTTGTCCTTTTATCAATAAGTTGTGCAGCATAAATTTTGACAGGCTTTCCC4980               AAACTAAATCTTAAAATGTCTAATTCTAAAATGTCTAATTCTAAAAGTTGGTTCATACTT5040               TCTTTAATTAATTGTTCTGTAGTAATAGCGTTAAAATCGGGTAATAGTAATTTGACGGGT5100               TTATTAAGATTTGATTTAAATACGAGTTCCAAAGTTTTTGACATACTGATGTATCCTCCT5160               TAAATTAAAGATTCTGTTTTAACGATCTCGACTTTGTCATACTCTTCGCCACTGAACGTT5220               CAATGATGGAACGAAAAGATTTGATTTGATCATTAGAAACAAGCGGATTAATGTTAGAAA5280               AACGACGCTTATGTTCGACTACTTTACCTTCAGAATTATGTTTGATTTGAGTAAAGATAA5340               TCGTCACTTGATTGACTTCATTCATAATAAAACCTCCTTTCACTATATATATCGAAATAG5400               ATTGAAAAAAAAGGACACATTTTTTGAAAAATATAGGCAAATGCCTTTGATGTGATACAA5460               ACGTCATTTATCATTAATTATGAAACCTGTTTTAGAAGGTATATGAGGTAAGTAGAATTG5520               TTAAGTTGTAAAAGAAAAAATTGGAACCTGATATTTAAAATAACCAACTTAAAAGATTGA5580               TCAGTGTCTAAAATTACTATTTATATATGAATTAAAATATTAAGATCTCCCAATATGAGA5640               ATGAATTAGTTTAAGTTTATCGATGATTGAAAAATTATAGCCTCATGGATTCTATCTTAT5700               ATAAAATAAAGTTCTATTCCCTTTTGGATATAAATAAGAATAGTTACCTTTTTGTGATAT5760               GCCAATTCAGAAAAAAAGCGACAGTGCTTGAATCTATGTATGCTCAATAAACTCATTCAA5820               ATCAACTAGCAATATCAAATCATAAATCGTGTTGCACCATAATAAGGATTAAAACCTGTT5880               AGTTTAACTAATTTAAGAAAAACATTTGATTATCTTCTCTTTCAATCGGGAATATTAATT5940               TCTATCATTCAACAATATTTTGGATATCAGATAACTTAAGAAATATTGAGATTTATTGAA6000               ATACGATATGTTTCAAATCGCCATACAATGATTACACTTAATAAATGATTACACTTAATA6060               TAAATGTAAAAAGAAAAGGAGGGGTTAAATGAGTTTAGTATATCTTATGGCGACTAATTT6120               ATTAGTCATGCTCATAGTTTTATTCACTCTGAGTCATCGTCAACTAAGAAAGGTTGCGGG6180               CTATGTTGCATTAATAGCTCCTATTGTGACATCTACATATTTTATTATGAAAATACCAGA6240               TGTGATTCGAAATAAGTTTATTGCTGTTCGATTACCATGGATGCCTTCAATTGATATTAA6300               TTTAGATTTAAGATTAGATGGTTTAAGTTTAATGTTCGGCTTAATTATTTCGCTAATAGG6360               TGTGGGTGTATTTTTTTATGCTACGCAATATTTATCCCACAGTACGGACAATCTTCCTAG6420               ATTTTTCATCTATTTACTATTATTTATGTTCAGTATGATTGGCATTGTAATAGCTAATAA6480               TACCATCTTAATGTATGTATTTTGGGAACTCACAAGTATTTCCTCATTCTTGCTTATATC6540               CTATTGGTACAATAATGGTGAAAGTCAATTAGGCGCCATTCAATCTTTCATGATTACAGT6600               GTTTGGTGGGCTAGCGTTATTAACAGGATTTATCATTTTATATATCATTACAGGAACAAA6660               CACAATTACTGATATCTTAATCAACGCAATGCAATTTCACGACATCCTTTATTTATACCA6720               ATGATTTTGATGCTATTATTAGGTGCTTTTACCAAATCTGCACAATTTCCGTTTCATATT6780               TGGTTACCAAAGGCCATGGCAGCACCTACACCAGTAAGTGCTTATCTTCATTCGGCAACA6840               ATGGTAAAGGCTGGAATCTTTTTACTATTTAGATTTACACCTTTATTGGGACTTAGTAAT6900               GTTTATATTTATACAGTGACATTTGTTGGTCTAATAACTATGTTATTTGGATCTTTAACT6960               GCTTTACGACAATACGACTTAAAAGGTATACTCGCTTATTCTACAATAAGTCAATTAGGT7020               ATGATTATGACAATGGTAGGTCTAGGTGGCGGTTATGCTCAGCACACATCAGATGAATTG7080               TCTAAGTTTTATATTTTAGTTTTATTTGCTGGCTTATTCCATTTAATGAATCATGCGGTT7140               TTTAAATGTGCATTATTTATGGGCGTTGGTATCATTGATCACGAGTCCGGAACACGTGAT7200               ATTCGTTTGCTAAATGGTATGCGTAAAGTCTCCCCTAAAATGCATATTGTCATGTTGCTC7260               GCTGCATTATCTATGGCAGGTGTTCCTTTTTTAAATGGCTTTTTAAGTAAGGAAATGTTT7320               TTAGATTCGTTAACTAAAGCAAACGAACTTGATCAATATGGCTTCGTATTAACGTTTGTG7380               ATTATTTCAATAGGTGTCATCGCGAGTATATTGACTTTTACTTATGCACTTTACATGATA7440               AAAGAAACATTCTGGGGAAATTACAATATAGAAAAATTTAAACGTAAACAAATACATGAA7500               CCATGGCTATTTAGTTTACCAGCTGTGATTTTAATGTTACTCATTCCAGTTATCTTCTTT7560               GTTCCAAACGTTTTTGGCAACTTTGTTATTTTGCCCGCAACCAGATCTGTATCTGGGATA7620               GGGCGGAGGTTGATGCATTTGTGCCACATATTTCTCAGTGGCATGGTGTGAATCTCCATT7680               AATTTTAAGATAGTGTATATATTGGACTATTTTAGCTCTAGTGTGATTGGAAAGAGGTTA7740               CGCATCAAATAATCAAAAGTGCTCGATTACAGTGGCTATCGGAAATTTATAGAGAATTTG7800               AATTATACTCAGCCCGTGGTATACGTGCATTGATGAATAATAAATTGAATTATTACATCA7860               TGATTACATTATTTATTTTTGTAGCTATTGTAGTTATGGATATTTGACTGTGGGTTTTCC7920               TCATGTACTCAGCTTCATATTAGTTCTTTCGGACCGTTGGAAGTTATCTTATCAGTTGTA7980               ACATTGATTATCGGCATTTCATTAATCTTTATTCGTCAACGACTAACGATGGTGGTATTG8040               AATGGAATGATTGGATTCGCAGTTACATTATATTTTATTGCAATGAAAGCTCCAGATTTA8100               GCTTTAACACAGTTAGTTGTTGAAACTATTACGACAATCTTATTTATTGTTAGTTTTTCG8160               AGACTACCTAACATCCCTCGAGTTAAGGCAAATTTAAAAAAAGAGACCTTCAAAATCATT8220               GTGTCACTTGTTATGGCATTGACGGTGGTATCACTTATTTTTGTTGCTCAACAAGCAGAT8280               GGTATGCCTTCAATTGCTAAATTTTATGAAGATGCATATGAACTTACAGGTGGAAAAAAT8340               ATTGTCAATGCTATACTAGGTGACTTCAGAGCTTTAGATACTATGTTTGAAGGACTAGTG8400               TTAATCATAGCTGGATTAGGTATTTATACGTTACTTAATTACAAAGATAGGAGGGGGCAA8460               GATGAAAGAGAATGATGTAGTACTTAAATCAGTTACAAAAATTGTAGTGTTTATTTTGTT8520               AACATTTGGATTTTATGTATTTTTTGCTGGCCATAATAATCCAGGTGGTGGCTTTATTGG8580               TGGCTTGATTTTTAGCTCGGCATTTATCTTAATGTTTCTTGCCTTTGATGTAAATGAAGT8640               GTTGAAAAAAGCTT8654                                                             (2) INFORMATION FOR SEQ ID NO:7:                                               (i) SEQUENCE CHARACTERISTICS:                                                  (A) LENGTH: 5024 base pairs                                                    (B) TYPE: nucleic acid                                                         (C) STRANDEDNESS: double                                                       (D) TOPOLOGY: linear                                                           (ii) MOLECULE TYPE: Genomic DNA                                                (vi) ORIGINAL SOURCE:                                                          (A) ORGANISM: Staphylococcus epidermidis                                       (B) STRAIN: Clinical Isolate SE- 32                                            (xi) SEQUENCE DESCRIPTION: SEQ ID NO:7:                                        AAGCTTTTTGATTTTTAAAGAAAAAATTAAACAAGGGGGCATTGCTTATGGTCAATAGAA60                 GAAAGATATCAATTATTGGCGCGGGACATACAGGTGGGACTCTAGCATTCATTCTTGCAC120                AAAAGGAATTAGGAGATATTGTGTTGATTGAACGCCAGCAATCAGAGGGTATGGCTAAAG180                GAAAGGCGTTAGATATTTTAGAAAGCGGACCCATTTGGGGGTTTGACACATCTGTACATG240                GTTCAGTAAATATAGAAGATATTAAAGATTCAGACATAGTGGTGATGACTGCAGGTATAC300                CTAGGAAATCAGGAATGACAAGGAGAAGAATTAGTTCAAACTAATGAACAAATAGTACGA360                GAAACTGCATTACAAATTGCAACGTATGCACCTCATTCAATAATTATTGTATTGACTAAT420                CCGGTTGATGTTATGACATATACTGCATTTAAAGCATCAGGTTTTCCTAAAGAACGTATT480                ATTGGTCAATCTGGAATTTTAGACGCTGCAAGATATCGAACTTTTATTGCTCAAGAACTT540                AACGTGTCTGTCAAAGATGTAAATGGGTTTGTTTTAGGTGGACATGGTGATACGATGTTA600                CCTTTGATTAATAACACACACATTAATGGGATTCCAGTTAAGCATCTTATTTCTGAAGAA660                AAGATTGATCAAATTGTTGAACGTACACGTAAGGGTGGTGCAGAAATTGTTGCATTACTA720                GGTCAAGGCTCAGCATATTATGCACCAGCAACTGCTATATATGAAACTATAGATGCAATT780                TTTAATGATCGGAAACGGTTATTACCAAGTATTGCTTATCTAGAGGGAGAATACGGTTGT840                TCAGATATTTGTTTCGGAGTTCCTACTATAATAGGATATCAAGGAATAGAAAAGATTATA900                GAGGTAGATATGAATAATGATGAGTATCAACAACTACAACACTCTGCGCAAGATGTGAGT960                GAAGTCAAAAACTCACTAAAATTCAAATAAATAATTATGAAGTTCTACATCTTAAATTGT1020               TAGATTTTTGTGAAAATTGTGTAAAGGGTATTTTTTCGTTGATTTATAAAAGCGCTTTCT1080               TGATATAATGAACATATATTCATAGAATAAGGAGACGATTAAAATGGCTAAAGGGGACCA1140               ATATCAAGCTCATACTGAAAAATATCATGAGTAAAAAGTCTAAAAAAAGTTATAAACCTG1200               TGTGGATTATCATTAGTTTTATTATTTTAATTACAATCTTGTTATTACCCACACCAGCAG1260               GATTACCTGTAATGGCTAAAGCAGCACTAGCTATTTTAGCTTTCGCTGTAGTTATGTGGG1320               TTACAGAAGCAGTTACTTATCCAGTTTCTGCAACATTAATTTTAGGATTAATGATACTTT1380               TACTAGGTTTAAGTCCAGTTCAAGATTTATCCGAAAAACTTGGAAACCTAAAAGTGGCGA1440               CATAATACTAAAAGGTAGCGATATTTTAGGAACGAATAACGCGCTTAGTCACGCTTTTAG1500               TGGTTTTTCAACCTCAGCCGTAGCACTTGTAGCTGCAGCATTATTTTTAGCAGTAGCTAT1560               GCAGGAAACCAATTTACATAAACGACTTGCATTATTTGTGCTATCAATTGTTGGAAATAA1620               AACTAGAAATATAGTCATTGGTGCTATTTTAGTATCTATTGTTCTAGCATTCTTTGTACC1680               ATCAGCTACAGCACGTGCTGGTGCAGTTGTCCCAATATTACTGGGAATGATTGCTGCATT1740               TAATGTGAGTAAGGATAGTAGACTTGCTTCATTATTAATTATTACTGCTGTACAAGCAGT1800               TTCGATATGGAATATAGGTATTAAAAACGGCTGCAGCACAAAATATTGTAGCCATCAATT1860               TTATTAACCAAAATTTAGGACATGATGTATCATGGGGAGAGTGGTTTTTATATCTGCGCC1920               GTGGTCAATCATTATGTCTATAGCTCTTTATTTTATAATGATTAAGTTTATGCCACCTGA1980               ACATGATGCAATTGAAGGTGGAAAAGAGTTAATTAAAAAGGAACTTAATAAATTAGGACC2040               AGTCAGTCATAGAGAATGGCGACTAATTGTGATTTCAGTGCTTTTATATTCTCTGGTCGA2100               CTGAGAAAGTATTGCATCCGATTGATTCAGCTTCGATTACACTAGTTGCTCTAGGTATTA2160               TGCTAATGCCAAAGATTGGTGTTATTACTTGGAAAGGTGTTGAAAAGAAGATTCCTTGGG2220               GGACGATTATAGTATTTGGTGTAGGAATCTCACTTGGTAATGTATTACTTAAAACAGGAG2280               CCGCTCATGGTTAGTGATCAACATTTGTTTGATGGGTCTTAAACATTTACCGATCATAGC2340               AACTATTGCGTTAATTACCTTATTTAATATATTAATACATTTAGGTTTTGCAAGTGCAAC2400               GAGCTTAGCCTCTGCGTTAATACCTGTGTTTATTTCTTTGACTTCAACGCTAAATTTAGG2460               TGATCATGCTATTGGTTTTGTATTAATACAACAATTTGTGATTAGTTTTGGTTTCCTACT2520               ACCTGTCAGTGCACCACAAAATATGCTTGCATATGGTACTGGGACTTTTACCGTAAAGGA2580               TTTTTTAAAGACAGGTATACCTTTAACGATAGTAGGTTATATTTTAGTTATCGTATTTAG2640               TTTAACGTATTGGAAATGGCTTGGTTTAGTGTAAGTAAAAGATTTAGGTATTAAAATGAT2700               AATTATAAATGTCTCGTAAAGTTTAATATTTTAACTTTACGACACATTTTTTATAAACTC2760               GTGGCAAGTTAATCTTAATAGTTGAAATGTATCGTATAAAAAATATATGAATGTAAATAG2820               AATTTAGTATTAGAGAATAACAAAAAATTGATGTTAGGTGGTAAAATCTAATGGCTATAG2880               GTGTCATATTAAATAGAGTTTTTAGGCTAAATAATAATCCATTATTTGATTATATATATA2940               GTAATAAAGAATCTATAAATCATTGTTATTTTATTATTCCAACTGAAGAGTTTGAAGAAG3000               AAGCAAAAAAGAAAGCACAATACTATTATGGGTCCATACAGAAGTTTATGTATGAACTAC3060               AACGATATGATATAGAACCCTTTTTGATGTCTTATGATAAATTAATAGACTTTTGTAAAA3120               AACAAGCTATAGACAAAGTTGTTGTTGCAGGTGATATTATGAGTTATCATCACGAAGAAT3180               ATGACATTTTACATCAAAGGAAACGATTTAAACAAGCTAATATTCAAGTAATATCATTAA3240               GAGCAAATCATTATTTTAACCCCCGCAAAACACATAATAAACAAGGGGAACCATATAAAG3300               TATTTACCAGTTTTTATAGAAAATGGCGTCCTTACTTAATGATTAGAGATGAATATGACT3360               ATCATTTAGAAGATATTTCAAAGGTTGTAGTGAAATCTCAACATAAAATTAAAGAAGATT3420               ATCATTCATATGGTATAAGTGAACGTGATGTTCAAAATCGTTGGTCTGAATTTTTATCTC3480               AAGATATCGAAAATTATAAAGAAAACAGGGAATACTTGCCTGAAGTATTAACAAGCCAAC3540               TAAGTATTTACTTAGCTTATGGAATGATAGATATTATACAATGTTTTCAACGATTTACTT3600               CAAAATTATGATAAAAATGAACAAAATTACGAAACTTTTATACGTGAATTGATTTTTAGA3660               GAGTTTTATTATGTATTAATGACCAATTATCCCGAAACAGCTCATGTTGCTTTTAAAGAA3720               AAATACCAACAATTGAAATGGTCTTATAATGAAGAGAATTTTAAACTGTGGAAAGATGGG3780               AATACTGGTTTTCCAATTATTGATGCAGCAATGGAGGAACTTAAAACAACTGGATTTATG3840               CATAATCGCATGAGAATGGTAGTTTCTCAATTTTTAACTAAAGATTTGTTTATTGACTGG3900               ATTTGGGGTGAGTCATTTTTCAAACAAAAATTAATAGATTATGATGCAGCTTCAAATGTT3960               CACGGATGGCAGTGGTCAGCTTCTACTGGAACAGATGCTGTACCATACTTTAGAATGTTT4020               AATCCTATAAGACAAAGCGAGCGTTTTGATAATAATGCACGATATATAAAAACTTACATT4080               CCAAGATTAAATCAGGTAGATGCTAAGTATTTACACGATACTCATAAATTCGAGCAACAA4140               ATAAAGGGGCAAGGTGTTGAAATAGGTAAAGACTATCCTAAACAAATGATTGATCACAAA4200               GAAAGTAGACAACGTGTAATGTCAGAATTCAAAGCTATAGATTAAATAAAAAAGATCTGA4260               ACAACATGATATAGGTGTTCAGATCTTTATCTAGTTACATAAAAAAGCAAACATGAATTA4320               AAATATATTCTAACAAAGTTAAAATATACATATATTTAAGATTTAATTTAGTTTTCAAAG4380               GTACTTCCCAATTTGTATAACGGGGCTCATAATAAAATAATTGCATCAAATATAATCCTA4440               TCCCTAACGGTAAACACATTAATAAAATAGCTTTAGTATAACTCCATCCTATTTGATGCC4500               ATAAATGACCTATCATAAGTTGAATAATGATGAGACATACCATTAAAATTACTTCAATTA4560               TCATTGGTATAATCTCACCCCTTTAATAAACAATATGACTGTTGCTTGTATGAGCACCAT4620               TAAAACGACAAATAGTAACGCTTTAACATCTATGATTAAAAAAACCTCTTTCACAATTTT4680               TAAAGGTGCATTTAATAAATAGACAGTATGTAATCTTAAGAATCGACCGATGTAAATACC4740               TAATCCATTTAAGAACATTAATATAACTATCAATAGTCGATTTAACCATACATAAGACGT4800               AAAATGTGCAATTTCTAAAAATATAAGAATTGTGAGGTATATTGCTAAGAGTACGCCAAG4860               TATTAAATAGGTGAAATAAATCCATTCTGTGATGTTTAATCCAGCTAAAAAGTTAAATTG4920               AAATTGGTTTAAGTGTATGAGATCGGTAATCATATAAAATGTGTTTGGAACTAATAATAG4980               AAATATGAGTCCGAAAACAATAAATAAGGGCCATTCAAAAGCTT5024                               (2) INFORMATION FOR SEQ ID NO:8:                                               (i) SEQUENCE CHARACTERISTICS:                                                  (A) LENGTH: 3287 base pairs                                                    (B) TYPE: nucleic acid                                                         (C) STRANDEDNESS: double                                                       (D) TOPOLOGY: linear                                                           (ii) MOLECULE TYPE: Genomic DNA                                                (vi) ORIGINAL SOURCE:                                                          (A) ORGANISM: Staphylococcus epidermidis                                       (B) STRAIN: Clinical Isolate SE- 37                                            (xi) SEQUENCE DESCRIPTION: SEQ ID NO:8:                                        AAGCTTGCCTATTGATTTTAAAAAATTAATGATTATAGGTTCACTCATATCTGTTGCAAC60                 TGCATCAGTGCCTATGTTTTTTGGGAAGCCATTTTTATATCAAACTGAAGCAAATGTAAC120                ATTTCCATTACTAGGACATGTTCATGTTACTACTGTGACTTTATTTGAGCTTGGCATCTT180                ATTAACAGTAGTAGGTGTGATTGTTACAGTTATGCTATCTATAAGTGGGGGTAGATCATG240                AATTTAATATTACTCCTTGTGATAGGATTTTTAGTGTTTATTGGAACTTATATGATTTTA300                TCTATTAATTTAATTCGTATTGTTATTGGTATTTCTATTTATACACACGCCGGTAATTTA360                ATTATTATGAGTATGGGGAAATATGGACCTCATATGTCTGAACCGCTAATTCAAGGTCAT420                GCTCAAAACTTTTGTTGATCCTTTATTACAAGCTATCGTTTTAACAGCTATTGTGATTGG480                ATTTGGTATGACTGCGTTTTTATTGGTGTTAATATATAGAACTTACAGAGTAACTAAAGA540                GGATGAAATAAGTGCATTGAAAGGTGATGAAGATGATGAGTAATTTAATAATATTGCCTA600                TGTTGTTGCCTTTTGTATGTGCTTTAATTTTAGTCTTCACTAAAAATAAAAATCGTATTT660                CGAAAATCCTATCCATTACAACTATGATTGTTAATACAATGATTTCAATTGCTTTACTTA720                TTTATGTCGTTAATCATAAACCGATAACACTTGATTTTTGGGGGGATGGAAAGCACCTTT780                CGGCATTCAATTTCTAGGTGATTCACTGAGTCTGCTTATGGTGTCAGTATCATCTTTTGT840                TGTTACGCTAATAATGGCATACGGCTTTGGTAGAGGGGAGAAGCGAGTCAATCGATTCAC900                CTCCTACATTATCTTTATTAACAGTAGGTGTTATTGGTTCGTTTTTAACTTCTGATTTAT960                TTAACCTATACGTGATGTTTGAAATTATGCTTCTTGCTTCGTTTGTACTTGTTACATTAG1020               GACAATCTGTTGAACAATTACGTGCAGCGATAGTATATGTTGTTCTGAATATTTTAGGTT1080               CGTGGTTGCTTTTATTAGGAATTGGCATGTTATATAAGACAGTCGGAACACTTAATTTCT1140               CACATTTAGCGATGCGATTGAATCATATGGAAAATAACCAAACAATAACGATGATATCTT1200               TAGTATTTCTAGTTGCTTTTAGTTCAAAGGCAGCACTAGTGATTTTCATGTGGTTACCTA1260               AAGCATATGCAGTGCTTAATACGGAACTTGCCGCGTTATTTGCAGCATTGATGACAAAAG1320               TTGGAGCTTATRCGCTTATTCGTTTTTTTACTTTACTATTCGACCATCATCCAAGCGTCA1380               CGCATACATTGCTCGTGTTTATGGCTTGTATCACAATGATTATCGGTGCATTTGGTGTCA1440               TCGCTTACAAAGATATTAAGAAAATTGCGGCTTATCAAGTTATTTTGTCTATTGGATTCA1500               TTATTTTAGGTTTAGGTTCTCATACTATATCAGGTGTAAATGGTGCTATCTTCTATTTAG1560               CGAATGATATTATCGTTAAGACATTATTGTTTTTTGTAATTGGTAGTCTTGTTTATATGT1620               CAGGCTATCGAAATTATCAGTATTTAAGTGGACTGGCAAAAGAGAACCATTCTTTGGTGT1680               TGCATTTGTCGTGGTAATTTTTGCTATAGGTGGCGTACCTCCTTTTAGTGGCTTTCCGGG1740               TAAAGTCTTAATATTCCAAGGGGCTATTACAAATGGTAATTATATTGGTTTAGCACTTAT1800               GATTGTGACAAGTTTAATTGCTATGTATAGTCTTTTTAGAGTGATGTTTATAATGTATTT1860               TGGTGATGCTGACGGAGAACAAGTACAATTTAGACCACTACCTATTTATCGTAAAGGTTT1920               ACTTAGTGTTTTAGTTGTAGTGGTATTAGCGATGGGTATTGCAGCCCCTGTTGTTCTGAA1980               AGTAACAGAGGATGCAACAAATCTTAATATGAAAGAAGATGTCTTTCAAAAGAATGTAAA2040               TACACATTTGAAGGAGGTTAATCATAAGTGAAGCAAGTTGTATTAAATATTGTTATCGCG2100               TTCCTTTGGGTACCCTTTCAAGATGAAGATGAATTTAAATTTACAACCTTCTTTGCTGGA2160               TTTTTAATTGGTTTAATTGTGATTTATATTCTGCATCGCTTTTTTGGTGAAGAATTTTAT2220               TTGAAAAAGATATGGGTGGCTATTAAATTTTTAGCTGTATACCTATACCAGCTTATTACT2280               TCTAGTATAAGTACCATAAATTACATCTTATTTAAGACGAATGAAGTTAATCCAGGTTTA2340               CTCACATATGAAACTTCATTAAAAAGTAATTGGGCTATTACTTTTTTAACGATTTTAATT2400               ATTATTACTCCAGGATCGACAGTTATTCGAATTTCTAAAAATACTAATAAATTTTTTATT2460               CACAGTATTGATGTGTCAGAAAAAGATAAAGAAAATCTTCTAAAAAGTATTAAGCAGTAT2520               GAGGATTTAATTTTGGAGGTGACACGATGATTGAAATGTTCACTCAAATATTTATTATAA2580               GTGCATTAGTGATTTTTGGTATGGCACTACTTGTTTGTCTAGTCAGATTAATTAAAGGTC2640               CCACTACTGCTGATAGAGTTGTATCATTTGATGCCTCGAGTGCTGTTGTTATGTCTATTG2700               TTGGTGTGATGAGCGTTATTTTTAACTCAGTGTCTTAATGTTAATTGCAATTATTTCGTT2760               TGTCAGTTCGGTCTCAATTTCAAGATTCATCGGGGAAGGACGTGTCTTCAATGGAAATCA2820               TAAAAGACATCGTTAGTCTTATTGCTTCGATACTTATTTTCTTAGGAAGTATTATTGCAT2880               TAATTAGTGCAATAGGGATTGTAAAATTTCAAGATGTCTTTCTAAGAAGTCACGCCTCAA2940               CGAAAAGTTCTACATTGTCAGTATTACTAACTGTAGTTGGTGTACTGATCTATTTTATTG3000               TGAATTCAGGTTTTTTCAGTGTCAGATTATTATTATCACTAGTTTTTATCAATCTTACAT3060               CTCCGGTTGGAATGCATTTGATAAGTAGAGCGGCCTACCGTAATGGTGCATATATGTACA3120               GGAAAGACGATGCATCTAGACAATCTACTATCTTATTAAGCCAAAAAGAGTTTAATACGC3180               CAGAAGAATTAAAAAAACGTGCAAAACTACGAGAAGAAAGACGAGAAAAATTATACTATA3240               AAGAAAAAGAATATATTAATAAAATGGACGATTGATTGTTTAAGCTT3287                            (2) INFORMATION FOR SEQ ID NO:9:                                               (i) SEQUENCE CHARACTERISTICS:                                                  (A) LENGTH: 2291 base pairs                                                    (B) TYPE: nucleic acid                                                         (C) STRANDEDNESS: double                                                       (D) TOPOLOGY: linear                                                           (ii) MOLECULE TYPE: Genomic DNA                                                (vi) ORIGINAL SOURCE:                                                          (A) ORGANISM: Staphylococcus faecalis                                          (B) STRAIN: Clinical Isolate S2- 1                                             (xi) SEQUENCE DESCRIPTION: SEQ ID NO:9:                                        AAGCTTTAGATAATGATAAACGCGTGTATGTGAATGTCCAGCCGATTCAATCGCCTACTG60                 GAGAAACAGTGATTGGTGTCCTTTATGTGAAAAGTAATTTAGAAAATAAATACCAAGAAA120                TTACTAACACAGCAAGTATCTTTTTCACTGCTTCTATTATTGCCGCAGCAATCTCGATTA180                TTGTGACCCTACTGATTGCACGATCAATCACGAAGCCGATTGGTGAAATGCGCGAGCAAG240                CCATTCGAATCGCTCGTGGTGATTACGCTGGAAAAGTAGAAGTCCATGGAAAAGATGAAT300                TAGGCCAATTAGCAGAAACATTTAATCAATTATCAGAACGGATTGAAGAAGCACAAGAAA360                CAATGGAAGCAGAAGAATCGTTTAGATAGTGTCTTAACGCATATGACAGATGGTGTCATT420                GCGACGGATCGCCGCGGAAAGGTGATTACGATTAATGAGATGGCCCTTTCATTATTAAAT480                GTAAAAAATGAAAATGTGATTGGGACCTCGTTATTAGAGTTGTTAGATATTGAAGAAGAT540                TACACATTGCGGAAGCTGTTAGAAGAGCCAGATGAACTGCTGATTGATCGCTCAACGTCT600                GATCGTGAAGAAGACCAAATGATTATCCGGGTAGACTTTACGATGATTCGTCGGGAATCA660                GGATTTATTACTGGCTTAGTTTGCGTACTTCATGACGTCACAGAACAGGAAAAAAACGAA720                CGGGAAAGACGGGAATTTGTTTCCAATGTTTCTCATGAGTTGCGACGCCTTTGACAAGTA780                TGCGTAGTTATATAGAGGCTTTGAGTGAAGGAGCTTGGGAAAACCCTGAGATTGCGCCGA840                ATTTCTTAAAAGTCACGTTAGAAGAAACCGACCGGATGATTCGTATGATTAATGATTTGT900                TAAATTTATCTCGGATGGACTCTGGGAATACACATCTTCAATTAGAGTATGTGAATTTTA960                ACGAATTGATTAATTTTGTCTTGGATCGCTTTGATATGATGATTGAAAATGAGCAAAAAA1020               ATTACAAAATTCGCCGTGAATTTACTAAACGCGATTTATGGGTAGAGTTAGATACAGACA1080               AAGTAATTCAGGTTTTTGACAACATTTTGAACAATGCGATTAAGTATTCGCCAGATGGCG1140               GCGTCATTACCTGCCGACTAGTTGAAACACATAATAATGTCGTCTTTAGTATCTCGGACC1200               AAGGTTTGGGCATCCCTAAAAAAGATCTCGGGAAAGTCTTCGAGCGTTTTTATCGTGTGG1260               ATAAAGCACGTGCGCGAGCACAAGGTGGGACTGGTTTAGGTTTAGCAATTTCTAAAGAAG1320               TAATTCGGGCCCATAACGGGAGTATTTGGGTGGAAAGTACAGAAGGTGAAGGATCAACTT1380               TCTATATTTCACTACCATATGAACCTTATGAAGAGGATTGGTGGGAATGATGAAAAAATC1440               AGAATGGATTACAAGAATTGGCTTGATTTTGATGGTCATTTTAAGTATATATTTTTCAGT1500               CAATATCTGGCTGAATTCTGCCAAAAAAATACCAGAAATGAAGTCGGGAAGCCAAGTCAC1560               AACAGCTGTCAATGAAAAAGCCATTGGCGATGTCTATTTACCTTTGCAATTGATTCGAAT1620               AGCCGATGGAAAAGCGATGCAAAGTAATCGTGAAACATTAATTAGTAATGTTCAAAATGA1680               TATTAAAATGGCTACGTTTGGTAAATTGACACAAGTTGTGACAAAAAATGCAGAGCAACT1740               TAAGCGCTACAACCAAATGGAACAAGGCATTGAACTTCTTTATCAAGGTCCCTTTTTAAT1800               CTCGGACTATGCTTCGATTTATAATCTATCCATTAATTTTACTAACTTTAATGAGTTGAC1860               GGACCAGTATTTTACGAAAATTCAATTGGATTTTAACGAAAATAAGATACGTTTTTTAGA1920               TTATGATCAATCCAACGTCTATGAAGCGCCCATGACTGTTAATAAGGCGCGCTTAATGGG1980               AATTATCAATAAAGAGGGATTGCAATATCAAGACGTTTCCGAAAATACGCTAACCAAACA2040               AGGACAATGTTATTTAACCAATGATATGAAGTTGAAAAAGTACAGTTATATCTTANTTCG2100               CAACCAGTTACTCGTTTTAGGAATGCTTTTTTCAATGAAACGGAAGATATCCAAACCAAT2160               GAAGACAGTCAAGACTTAACCTATACGAGTAAAGAAGAACGATTGTTTGCAGAAGAAAAA2220               CTGGGGAAAATCGATTTTAAAGGGACCTTGCCAGAAGAGAATAAACGGGACTCAATCTAT2280               AATCAAAGCTT2291                                                                (2) INFORMATION FOR SEQ ID NO:10:                                              (i) SEQUENCE CHARACTERISTICS:                                                  (A) LENGTH: 3719 base pairs                                                    (B) TYPE: nucleic acid                                                         (C) STRANDEDNESS: double                                                       (D) TOPOLOGY: linear                                                           (ii) MOLECULE TYPE: Genomic DNA                                                (vi) ORIGINAL SOURCE:                                                          (A) ORGANISM: Enterococcus faecalis                                            (B) STRAIN: Clinical Isolate S2- 3                                             (xi) SEQUENCE DESCRIPTION: SEQ ID NO:10:                                       AAGCTTCATTAGAGCGTCAACTGTTTTTGGTGTTGGGTTCACAATGTCAATTAGACGTTT60                 GTGAGTACGCATTTCGAATTGTTCGCGAGAATCTTTGTATTTATGAGTCGCACGAATAAC120                TGTGTAAAGTGAGCGTTCTGTTGGTAATGGAATCGGACCTGATACGTCAGCTCCAGTTCT180                TTTTGCTGTTTCCACAATTTTATCCGCTGATTGATCTAAAATACGGTGTTCATACGCTTT240                TAAACGGATACGAATTTTTTGTTTTGCCATCTTGTTCCCTCCTTCGCCTATTTTAAAAGT300                AGACATAGCTCCACGAAAATTTATCCGGCATGCTCGTTCATGGCAAAGCGTCCGAGCGTG360                TCGCAACCTCTCGCTTCACAGCCGGCAAATCAAATCGTTGATCTACCAATGCTTTTTACA420                CTCCTGTAAACAGCACCTTTTTGATTATACTATGAAAGGATAGTGTTAGCAAGGATTTTC480                TGCGTTTTTTTAAAAGAATTTTTTCTTGTTTTGAAAAGCATTTGTTTTGTTTTTCAATTC540                TTTTCATTCTATTTTTATAAAAAAAGAATTTGAGATTCTTTTTTTACCAGAATCTCAAAT600                TCTTTCTTTTTTATTCTATTAACCAATCCGGCGCATTGGAATATCATTGTTATCTGGATG660                AACCAATAAATATTGAATAACATCAATATTGCTTGCTTGGAATGAGGCTGCACATGCTTG720                CAAATATAAGTCCCACATTCGATAGAAGCGCTCGCCTTTTTCGTCAACAATTTCTGTTTC780                TATATTATGGAAGTTTTTTGTCCAATGTTCCAACGTCAATTGATAATCTCTGCGCAAACT840                TTCCAAGTCAATCACTTGCAAGTCGTTTTCTGTCATATGGCCGACTAGCTCAGTGACACC900                AGGAATATAGCCACCTGGGAAAATATAACGATTAATCCAAGCATTTTTAGCCCCACCTTG960                TTGGCGACTGATCCCATGAATCAACGCCGTACCTTTAGGCGCTAAATTTCGCTGAACGAC1020               ATCAAAATATTCATGTAGATTTTCCGCACCGACATGTTCAAACATCCCAACACTCGTAAT1080               ATGGTCAAAAGACTCTCCTTTTAAATCACGATAATCCATCAATTTGACAGTCATTCGATC1140               TTGTAGACCTTCTTTTTCTATAATATGGCGAATATGATGAAATTGCTCTTCACTTAATGT1200               AATCCCAGTTGCTTTGGCTCCATATTCTTTCACCGCAGTTAAAATTAACGTGCCCCAGCC1260               GCAGCCAATATCCAGTAAAGTGTCGCCCTCTTTGATAAACAATTTATCTAAAATATGATG1320               AACTTTATTCACTTGCGCTTGTTCTAATGTATCTTCAGGCGTTTTAAAATAAGCACATGA1380               ATACGTCATTGTTTGGTCAAGCCATTTTTTGTAAAAATCATTTCCTAGATCGTAATGGCT1440               GTGAATATCCTCTTGCGAACGTTTTTTTGAATGACTTTCTTTAGGAAGCCATTTAATAAA1500               TTTAGCATTGTGTAAAAAGCTATCCTTTTGGTTATACACATCATAAATCAGCGCTTGGAT1560               ATCGCCTTCGATTTCAATTTTGCGATCCATGTAGGCTTCCCCTAAAGTTAACGAAGCGTT1620               ATTCAGTAAATCCTTCACAGGAATTTTTTCATTGAATACAATTTTAAAAACCGGATCCCC1680               CGACCCTTGCCCATACTCTTTGACGGTACCATCCCAGTATGTGACTTGTGTCTTTTTTGA1740               AAAAGACCATTTAAACAGTTGACTGTACGTTTCTTTTTCTAACATTGCATTCCCTCCATT1800               AAATACCATTTGAAGCCAAAACAAAAAGAAGTCGCTTTCCGGTAGTTCGTCAAAACAAAC1860               ACCACAGTCCGTTCTAAACTGAAGCACAGAAAAGTTATCACCCCTTCTATGTTCCGCTTC1920               TTTTTTGCAATTACAGTTCTATTCTACTCCTCTTTTAAAAATTTGAACATTCTTTTAACG1980               TAATACCTACTATTGTTATTCTTTATCACAAAAAAACTAGAGCCAGTCCTTGACAGACTC2040               CTCTAGTTCTAAATATTATGCTTTCTTACGCATCCGTTGTTCCGCATGAGTGTAAGCGCC2100               ATGCCACACGTGCCCCACATAAGGATTAACTTGAATACCGTGTTTAATCGCCGCTGCTAC2160               AAATTTTTCGCTAAAGTTACTGCTTCTAACACCGAATAACCTTTCGCCAAGCCAGCTGTG2220               ATTGCCGCTGAAAAAGTACAACCTGCACCATGATTATAATCAGTTGGATATAATTCATTT2280               TCCAAAAGATGCGCGGTGTGACCATCGTAAAATAAGTCCAGTGCTTTTTCACCAGCTAAG2340               CGATGTCCCCCTTTAACCACGACATGCTTGGCTCCCATTTGTACAATTCGTTTTGCCGCT2400               TCTTCCATCTCCGCCACGGAAGAAATTTCGCCTAAACCAGATAAGATGCCCGCTTCAATT2460               AAATTAGGCGTGGCAACTAATGCTAATGGCAGTAAATCGTTTTTAGGCCTTCCACACTTT2520               TGGGTTGCAGAATTTGTGCCGTTCCCTTACAAGCAATGACTGGGTCAATCACGACTTTTT2580               GAATTTTTTCTTGTTTAATGTACTTACTAGCCATTTTAATATTTTGTTCATTACCCCATC2640               ATCCCCTGTTTTCAAAGCCGCTACTGGACCGCCTGCAAAAACCGAAATCAATTGTTTTTC2700               TAAGAGCGTTTCTGGCAATTCAGTTACTTCATGTGACCAACCTGTCGTAGGATCCATCGT2760               CACAATCGAGGTTAAACTTGAAAATCCAAAAACTCCATACTCTTCAAATGTTTTTAAATC2820               TGCTTGAATCCCTGCCCCTCCAGTTGAATCGGAGCCTGCAATCGTCAATACTTTTTCCAT2880               TAAATCACCTAACCTTTTTCTCCAAGTATACGGAAGAAACAAGTCTGCTAAAACAGCCAA2940               TTGGCTTATTTTTTAGCCAGCCAATTTCTAAACAAAAAAAAGACCAGAGAATAAATTCTC3000               TGGTCTTACGTCCGAATACCCCAGTTTTTCACGCTGGTTAAAGCTATAGTTAAAAAGTTA3060               ATTATTTAACGATTTCAGTAACAACGCCTGAACCTACAGTACGTCCGCCTTCACGAATAG3120               AGAAACGAGTTCCGTCTTCGATAGCGATTGGGTGAATTAATTCAACGTCCATAGCAACGT3180               TATCACCAGGCATTACCATTTCAGTACCTTCTGGCAATTCTACAACACCAGTAACGTCTG3240               TTGTACGGAAGTAGAATTGAGGACGATAGTTAGTGAAGAATGAGTGTGACGTCCGCCCTC3300               TTCTTTTGATAATACGTATACTTCAGCTTTGAATTTTGTGTGTGGAGTGATTGTAGCTGG3360               TTTAGCTAATACTTGTCCACGTTCGATATCTTCACGTGCAACACCACGTAATAAAGCACC3420               GATGTTGTCGCCTGCTTCAGCGTAGTCTAATAATTTACGGAACATTTCAACACCTGTAAC3480               AGTTGTTTTAGATGTTTCGTCTTTAATACCAACGATTTCAACTTCGTCACCAACGCGAAC3540               TTCACCACGTTCAACACGGCCTGTAGCAACAGTACCACGTCCAGTGATTGAGAATACGTC3600               TTCGACTGGCATCATGAATGGTTTGTCAGTATCACGTTCTGGAGTTGGGATATATTCGTC3660               AACTGCAGCCATTAATTCTAAGATTTTTTCTTCATAAGACTCGTCGCCTTCTAAAGCTT3719                (2) INFORMATION FOR SEQ ID NO:11:                                              (i) SEQUENCE CHARACTERISTICS:                                                  (A) LENGTH: 3480 base pairs                                                    (B) TYPE: nucleic acid                                                         (C) STRANDEDNESS: double                                                       (D) TOPOLOGY: linear                                                           (ii) MOLECULE TYPE: Genomic DNA                                                (vi) ORIGINAL SOURCE:                                                          (A) ORGANISM: Enterococcus faecalis                                            (B) STRAIN: Clinical Isolate S2- 7                                             (xi) SEQUENCE DESCRIPTION: SEQ ID NO:11:                                       AAGCTTCTAGCGTTTCGGATTGGCGCCTATGATGCACCAGGAGAGCGACGAATCAATACC60                 AAAAATATGCCTACAGCAGGAGGACTTGCAATCTACATTGCTTTTGCTAGTTCATGTTTA120                TTGATTTTTCGTTCGATTATCCCACAAGATTATATTTGGCCGATTATTTTGGCTGGTGGA180                ATGGTTGTTTTGACAGGCCTCATTGATGATATTAAAGAGATTACTCCAATGAAAAAAACA240                ATCGGTATTTTGTTAGCAGCATTAGTTATTTTATTTTGTTGCTGGAATTCGGATAGATTT300                TGTGACGTTGCCAGTTGTTGGAATGATTGATTTGCGCTGGTTTAGTTTACCACTAACTTT360                ATTGTGGATTTTAGCGATTACGAATGCAGTAAATTTAATTGATGGTTTGGATGGTTTAGC420                ATCAGGCGTATCCATTATTGGATTAACCACGATTGGTATTACAGGGTATTTTTTCCTACA480                TGCTAAAACGGTCTATATCCCAATTGTTATTTTTATTTTAGTTGCGAGCATTGCGGGATT540                TTTCCCATACAATTTTTATCCGGCTAAAATATTTCTAGGAGATACCGGGGCGTTATTCCT600                CGGGTTTATGATTGCAGTAATGTCGTTACAGGGCTTGAAAAATGCTACGTTTATTACGGT660                AATTACGCCAATGGTGATTTTAGGTGTGCAATTACGGATACGGTTTATGCAATTATTCGA720                CGGCTATTGAACAAGAAGCCCATTTCCTCAGCAGATAAAATGCATTTACATCACCGCTTG780                TTATCTTTAGGTTTTACCCATAAAGGGGCGGTCATGACTATTTATGCATTAGCGTTAGTT840                TTTTCCTTTGTCTCTTTATTGTTCAGCTATTCAAGTACAGTAGCATCAATTTTATTAATT900                GTCTTTTGTTTAATTGGCTTAGAACTATTCATTGAACTAATCGGTCTAGTTGGCGAAGGG960                CATCAACCGTTGATGTATTTGTTACGGATTTTAGGGAATCGTGAATATCGTCAGGAGCAA1020               ATGAAAAAGCGACTTGGCAAGCATTCTAAGAGAAAGTAAAGAAATCTTTAGGTTGCTTTG1080               CGAGAGCTAAACCTATGATATAATTCCATTAAACTTAAAAAAGTATATGTGTGAAACATA1140               TGCTTTTTTTTTAAGACGATGTTTCAGTAGTAAGGAGAAATGAGCATGCAAGAAATGGTA1200               ACAATCTCGATTGTCACTTATAATAGTCGTTACATTTTTAATGTACTAGACCAATTAAAA1260               GCCGAACTAGGTACTGATAGTATCTATGATATTCATATCTATGACAATCATTCTGAAACA1320               GCGTATCTTGAAAAATTAACAACATATGAACCATTTATTACTATCCATCGCGCTGAAGAA1380               AATCAAGGGTTTGGTCATGGTCATAATCAAGTGTTATTCAATGCTTCGACAAAGTATGCA1440               ATTATTTTTATCCCGATGTGTTGGTTACTAAAGACGTGCTTGATCGTTATTAGACGTATC1500               AAATAGATAAGAACATTGCAGTCGGTAGCCCTAAAGTTGTTAAATGAAGATGGCACGACG1560               CAATATTTAGTTCGTCAAAAATTAGATGTCTTCGATTATATGTTACGTTTTATTCCCTTT1620               CAATTTGTAAAGAAAATTTTTGATAAACGTTTGAGTATTTATGAATGTCGCGATTTGTCG1680               GATACAGAAACAACGGATATTAAAATGGGCTCAGGCTGTTTTATGTTGATTGATCGTGAA1740               AAATTCGTTGAAATTGGTGGGTTCGATGAACGTTTCTTCATGTACTTTGAAGACAACGAT1800               TTATGTTTACGCTTTGGCAAAGCAGGCTATCGGATTCTCTATACGCCTTTTGAAACGGTT1860               GTTCACATGTATGAAAAGGGCGCCCATAAAAGTCGAAAATTGTTTAAAATCTTTATGCAA1920               TCAATGGGGAAATTTTTTAACAAATGGGGCTGGAGGTTCTTTTAATGAGTCAAAGATTAG1980               CGGTAGTCATCGTCTTATATCAAATGAAAATGGCTGATACGCCGAATTATTTGTTATTAA2040               AAGAAGTGGTAGACCACCCCCAATTGCACTTATTTATTTATGACAACAGTCCACTTCCTC2100               AAGAAGATGCATTATTTTTACAACCAAATGTTACTTATCGACATAATCCTGATAATCCAG2160               GACTAGCGACCGCTTATAATGAAGCGATTGCTTTTAGTCAAGCGAATCAATGTGAATTAT2220               TGTTGCTCCTTGACCAAGACACAGAAGTGCCAGCCTCTTATTTTGATACGTTGATCATCA2280               TGCCATTAGATCCGACTGTGGCAGTCTATGTTCCAATTGTAGAAGCAAATGGACAACAAA2340               TTTCGCCAGTATATAGTGATCAATACGTTGGGCTTAAAGGAGCAAAGCCAACAGCAGGGA2400               TAGCCAACCAACCGTTGATGGCTATCAATTCTGGTACAGTTATTACGGCAGAAACGCTAC2460               GCTGGTTGGAAGGATTTTCGGAAGAATTTCCTTTGGACTATTTAGACCATTGGTTCTTTT2520               ATCAATTAAATCAAGCCAATAAAAAGATTGAAGTCTTACCAATCCACCTAAAACAAGAAT2580               TGTCTGTTTTAGATTATCGTACAATGAGTCCTCAACGTTATCGCTCTATTATTGAAGCAG2640               AAACGTTATTTTATCGTCGATATGATCAAGAAAAGTTTTCCCATCATCGACGCCATTTAT2700               TTTTACGCAGTAGTAAGCAATTTTTAACTGTCAAAAATCGCCAAATTTGGCGGCAAACAT2760               TGGCAGAATTTCTCAAGTTAATGAAAGGATAATCTATGATCTCAGTTTGTATTGCGACAT2820               ATAATGGAGAAAAATATCTCGCGGAACAATTAGATAGTATTCTTTTACAAGTCAGTGAAG2880               AAGATGAACTAATTATTTCAGATGATGGTTCTACTGATCATACGTTGGAAATTTTGAGGA2940               CGTATGCAGCGAATTATCCCCAAATTCAATTGTTACAAGGTCCCAGGGCAAGGAGTGATT3000               GCTAATTTTGCATTTTGCCTTACGCATACGAAAGGCGAAGTAATATTTTTAGCAGATCAA3060               GATGATGTTTGGTTGCCAAATAAAGTAACGACGGTGACAGAATATTTTGAAGCGCACCCT3120               GACATCCAAGTGGTTATTAGTGACTTGAAAATTGTTGATGCGGATTTACAAGTTACCAAT3180               CCCTCTTATTTAAGTTTCGAAAAGTCAAACCAGGGTTTTGGCGAAATGCGATAAAAAGTG3240               GCTATATTGGGGCAGGTATGGCCTTTCGTCAAGAAATGAAAAACGTCATTTTACCCATTC3300               CGCCAGAAGTTCCTATGCATGATATGTGGATTGGCTTATTAGCTGCACGGAAGAAGCAAA3360               CGGGTCTCATTAAAGAACCATTAGTGCTTTACCGAAGACATGGAGCGAATGTCAGCCCCA3420               TTATTACCAAAACAAGTTTCCAACAAAAATTAAATTGGCGTGTGAATTTATTAAAAGCTT3480               (2) INFORMATION FOR SEQ ID NO:12:                                              (i) SEQUENCE CHARACTERISTICS:                                                  (A) LENGTH: 2441 base pairs                                                    (B) TYPE: nucleic acid                                                         (C) STRANDEDNESS: double                                                       (D) TOPOLOGY: linear                                                           (ii) MOLECULE TYPE: Genomic DNA                                                (vi) ORIGINAL SOURCE:                                                          (A) ORGANISM: Enterococcus faecalis                                            (B) STRAIN: Clinical Isolate S2- 27                                            (xi) SEQUENCE DESCRIPTION: SEQ ID NO:12:                                       AAGCTTCTGCGCTAGGAACCAGCCCTTTAATTACATCTCCCCATACTGGATTTGACAATG60                 CCACTTGATAAGCAAAAATCACAAAAATAACAACAATTAAAGCAACAACAATAGCTTCAA120                TTTTTCTAAAACCAATTTTTGTCAATAACAACAAAAGTAAAACATCAAATACCGTAATGA180                AGACAGCCAGACCTAAAGGAATATGAAATAATAAATATAAGGCAATTGCGCCCCCGATAA240                CTTCAGCGATATCTGTAGCCATAATTGCTAACTCTGTTAAAATCCATAATACAATACCTA300                ACGTCTTACTAGTTCTAGCACGAATCGCTTGTGCTAAATCCATCTGTGAACAATGCCTAA360                TTTAGCAGCCATATATTGGAGCAACATTGCAATCAAACTGGAAATTAAAATAATCGACAT420                CAATAAATATTGAAAATTTTGTCCCCCAGTAATTGAAGTAGACCAGTTTCCTGGATCCAT480                ATACCCCACTGCTACCAATGCTCCTGGACCTGAGTAAGCAAATAACGTTTTCCAAAAACT540                CATATTTTTAGGCACGTCGATGGTGCCATTAATTTCTTCAAGCGAAGGACCATTTGCATA600                TTCAATCAAATGATGTCTTTGCTTTGGTTCATGTTCTTCTGAATTTTTCAATTCAATTCC660                TTCTTTCGTTTTGCAATAATTTTAAAAGGCCCTTCCCGTTAGAAGGTTAACCTCTAGTAT720                ATTTTAGGTACACCTAAAATATACTGCTAAAAATAACAAAATGCAAGACTTGAAAGAAAA780                TTTTGACAGTGTAAAAATAGATTGTCGTAAATGTGCGATCTTAAAGTTTGAAGAAATCAG840                GGTAGCTGGTAGTTGATTATCTTAAGAAGTAGAAAATAAGGGACCTAAGTCATTTCGGCT900                TAGGTCCCTTATTTTATTTTTATTCGGTTATTCTATTAAGAATGGATGCTACAATTTCTG960                TCGTGTCAGCTGAATGATTTCTAAAATCTCGTAAACTTAATCTGACGAAAACCTTCAAGT1020               ACTTCGGGCAACTTATTTTNCCCCCATTCAAAAGTTCCATCATTTCTTTTCAATAATCTT1080               TGTAAAATTTCTTCTTTCTCGACCGCTAACAAAAAATGATAAACGTCAATGCCTGCTCGT1140               CTCAGATATCCAATCAGCTCTTCTTCATATTCATTTTTATAAAGGGTCATTGTAACAATA1200               ATCGGCCGTCCAGACTCTTTGGACATTCGTTTTAATAAATGAGCATTCCAGCAACGCCAT1260               TCCTGATACTCCTGAAAATCATTTTCTTTCATTTCTTCGGGAACTAGCTCCATCAATGCA1320               CTACCAATAATTTCTGGATCATAAATGATTGCGTTGGGAAGTTTTTGTTGTAACTCATGT1380               GCAATGGTCGTTTTTCCGGATCCAAACGCACCGTTTAACCAAATAATTATCATAATTTCC1440               TTTTCTTCTGAACAAATTTCTTTGTTGTTTAATTTAGGTGCTAGATTACTTTTAATTTTT1500               TTAGCCATTCACTTATAGTTACTACTTACATCTTTAACAGTAAACGAGACAAACTAAAAA1560               TACAACATCCTACGCTATTAACCTCGGGTTATATAACATACTCATCTGATAATTTCTCCC1620               TAAAAAAACAGAATGTGGGCAATCTTTTTAAGAATAATTGAATAGAATAACAACAAACAG1680               TAATTCAGGTATAACCAGCTAGAAATTGTTTTATTTTTAGTCACGAGTATGATAAGCATG1740               TAAATCAAATAGAATCATATTAGGTGAGGTTACTCTGAAGAACACAGGTTATCGCTCGGA1800               AATGTCGAGAGACAGTAACGAGTAAAGCAGGGATTGTCGAATTAAGGCTTTCCTAAGATA1860               ACTAGAATTTTTTTCTTACGTCTCAGAAAGCCAAAGCTCAATTATTGTGATTACCCTATA1920               ATCTTCTTCTTTTATTCGGCGACCTCTTTAATATGATTAATTGGAGGTTTTTAAATTGAA1980               AGCTGTCACTGCATCATCTAAGAAAAATACCCTACTTGCTAAAAGTATCGGGAATCTTAC2040               CTTGCTCATCATTTTAGGCATTTTCATTTTTATCATCGTCTTCTCTTGGCTAAAAATGAA2100               TCGCCCTCTCCACACCCTTCCCTCAGAAGAATTCCTCGCAACACCAAGTAAAACAGATGA2160               TTTCTTATCTCCATCAAATCTTTTTTACTTTTCAATTCGAACCATGTTTCGAATGATTGT2220               GGGGATGGCTTGGTCCTTCCTGTTTTCCTTTGTTTTTGGTATTTTAGCCGTAAAATATAA2280               AACGGCACGAAGAGTCATTTTACCATTAGTTAATTTCCTTGAATCTGTTCCATTGCTAGG2340               TTTTTTGACCTTTACAACTGCTTGGTTACTTGGTTTATTTCCAGGAAATGTGATGGGCGC2400               AGAAGCGGTTGCTATTTTTGCCATCTTCACAGGTCAAGCTT2441                                  (2) INFORMATION FOR SEQ ID NO:13:                                              (i) SEQUENCE CHARACTERISTICS:                                                  (A) LENGTH: 9515 base pairs                                                    (B) TYPE: nucleic acid                                                         (C) STRANDEDNESS: double                                                       (D) TOPOLOGY: linear                                                           (ii) MOLECULE TYPE: Genomic DNA                                                (vi) ORIGINAL SOURCE:                                                          (A) ORGANISM: Pseudomonas aeruginosa                                           (B) STRAIN: Clinical Isolate P2- 2                                             (xi) SEQUENCE DESCRIPTION: SEQ ID NO:13:                                       AAGCTTTCCTCCAGACCCTTCACCGCCGTGGAGATCGACGGCTGGGCGATGTACAGCTTG60                 CGCGAGGCCTCGGCCACGCTGCCGCATTCCACGGTGGTCACGAAATACTTGAGTTGCCGC120                AAGGTATAGGACGCCACTGCAAGACCTCATCGGCGCATCATCCTCCCCGGGCCGGGCGTG180                CGCGCCTCGATTGTTGTGTCCGCCGCGCTGCAAGCAAGTTGCAGGCCGCTGCCGAGCGTC240                GCGCGCTGGCCGCGGAACGATTGCCCGCCTGCACGATAACCCAGCACGACGCACTTTGCC300                GGGGCACGCCTGGCCAGCTTTTTCTTATGTCCCGAGGACATTTTTAATAATTTTCCTTCG360                CCGCGGCTTGCGCGACCATCCTTCCCCATCGACCCCATGGACAGCGGTTCGCCTCCCGGC420                GGTCCGGGCCATGCGTGCAGAACCACGACCGGCGCAGACCGGCGAGATAACAAGGAGAAG480                GTGGGGTGTTCGAACTCAGCGATTGGCAACGGCGCGCCGCGACACAGCGCTTCATCGACC540                AGGCCCTGATCGGCGGCCGCCAGCGTCCAGCCGCCAGCGGCGCTACCTTCGACGCCATCG600                ATCCGGCGAGCAATCGCCTGCTGGCGCGGGTCGCGGCCTGCGATGCGGCCGACGTCGACG660                CGGCAGTGGCCGCCGCCCGCCGCGCCTTCGACGAAGGCCCCTGGGCGCGTCTCGCCCCGG720                TCGAGCGCAAGCGCGTGCTCTGCGCCTGGCCGAGCTGATGCTGGCCCATCGCGAAGAGCT780                GGCGCTGCTCGACTCGCTGAACATGGGCAAGCCGGTGATGGACGCCTGGAACATCGATGT840                ACCCGGCGCCGCCCACGTCTTCGCCTGGTATGCGGAAAGCCTCGACAAGCTCTACGACCA900                GGTCGCGCCGGCCGCCCAGCAGACCCTGGCCACCATTACCCGCGTGCCGCTGGGGGTGAT960                CGGCGCGGTGGTGCCGTGGAACTTCCCGCTCGACATGGCCGCCTGGAAGCTCGCCCCGGC1020               CCTGGCCGCCGGCAACTCGGTGGTGCTCAAGCCGGCCGAGCAGTCGCCGTTCTCCGCCCT1080               GCGCCTGGCCGAGCTGGCCCTGGAGGCGGGGGTGCCGGAAGGCGTGCTGAACGTGGTGCC1140               GGGCCTCGGCGAGCAGGCCGGCAAGGCCCTCGGCTTGCACCCGGAGGTGGACGCACTGGT1200               GTTCACCGGCTCCACCGAGGTCGGCAAGTACTTCATGCAGTATTCCGCGCAATCCAACCT1260               CAAGCAGGTCTGGCTGGAGTGCGGCGGTAAGAGTCCGAACCTGGTGTTCGCCGATTGCCG1320               CGATCTTGACCTGGCGGCGGAAAAAGGCGCCTTCGGCATTTTCTTCAATCAGGGCGAGGT1380               CTGTTCGGCGAACTCGCGCTTGCTGGTGGAGCGTTCGATCCACGACGAGTTCGTCGAGCG1440               CCTGCTGGCCAAGGCCCGCGACTGGCAGCCGGGCGATCCGCTGGACCCGGGCCAGCCGCG1500               CCGGCGCCATCGTCGACCGCCGGCAGACCGCCGGGATTCTCGCCGCCATCGAGCGGGCGC1560               AAGGCGAGGGCGCGACCCTGCTCGCGGTGGCCGCCAGTTGACGATCAACGGTTCGGACAA1620               CTTCATCGAACCGACCCTGTTCGGCGACGTACGCCCGGACATGCAGCTGGCCCGCGAGGA1680               AATCTTCGGCCCGGTGCTGGCGATCAGCGCCTTCGACTCCGAGGACGAGGCCATACGCCT1740               GGCCAAGGACAGCCGCTACGGCCTCGCCGCCTCGCTGTGGAGCGACGACCTGCACCGTGC1800               GCACCGGGTGGCGCGGCGCTTGAATGCCGGAACGTGTCGGTGAATACCGTGGACGCGCTG1860               GACGTCGCGGTGCCTTTCGGCGGCGGCAAGCAGTCCGGCTTCGGTCGCGACCTGTCGCTG1920               CATTCCTTCGACAAGTACACCCAGTTGAAGACGACCTGGTTCCAGTTGCGCTGAAGACGC1980               GACGGACGCGACACGACTCGATGCCGATAACGACAACAAGAGGACGATCGAATGAACGAC2040               ACGCCGAACGTGCGTGAGCCGGCCCTGCGCCGCGTGCTCGGGCTGGGACCGCTGCTGGCG2100               GTGGCCATCGGCCTGGTGGTTTCCCAGGGCGTGATGGTACTGATGCTGCAAGGCGCCGGG2160               ACGGCCGGCCTGGGCTTCATCGTGCCGCTGGGAGTGGCCTACCTGCTGGCGCTGACTACG2220               CCTTTTCCTTTTCCGAGCTGGCCCTGATGATTCCCCGCGCCGGTAGCCTGAGCAGCTACA2280               CCGAGGTGGCCATCGGGCATTTCCCGGCGATCCTGGCGACCTTTTCCGGCTACGTGGTGG2340               TGGCGATGTTCGCCCTCTCGGCGGAACTGCTGCTGCTCGACCTGATCATCGGCAAGGTCT2400               ACCCCGGCGCGCTGCCGCCGATGCTGGTGCTACGGCGTGCTCGGCCTGTTCACCCTGCTC2460               AACCTGCTCGGCATCGACATCTTCGCGCGCCTGCAGAGCGCGCTGGCGCTGCTGATGATG2520               ATCGTCCTGCTGGTGCTCGGCCTGGGTGCGGTGAGCAGCGACCACGCTTCCGCGCAGACC2580               GCCCTGGCGAGCGGCTGGAACCCGCTGGGGGTAAGCGCCCTGGCGCTCACCGCGATGGCC2640               GTGTGGGGCTTCGTCGGCGCCGAGTTCGTCTGCCCGCTGGTGGAGGAGACGCGGCGTCCG2700               GAGCGCAACATCCCGCGTTCGATGATCCTCGGCCTGAGCATCATCTTCCTGACCATCGCC2760               CTCTACTGCTTCGGTGCGCTGCTGTGCATCCCGCAGGCGGAACTGGCCGGCGACCCGCTG2820               CCACACTTCCTCTTCGCCAACCGCGTGTTCGGCGAGTACGGCCAGCTGTTCCTGGTGATC2880               GCCGCGATCACCGCCACCTGCAGCACCCTCAACTCGTCGCTGGCGGCGATCCCGCGGATG2940               CTCTACGGGATGGCGCAGAACGGCCAGGCCTTCCCGCAATTCAAGCAGCTCAGCCGGCGG3000               GCGCGCACGCCCTGGGTGGCGGTGCTGTTCGTCGCCGCGATCACCGGCCTGCCGATCCTG3060               ATCCTCGGCCAGGACCCGGACTCGATCAACCTGCTGCTGCTCGCCGCCGCGCTGGCCTGG3120               CTGCTGGCCTACATCATCGCCCACGTCGACGTGCTGGCCCTGCGCCGTCGCTATCCGCAC3180               ATCGCCCGTCCGTTTCGCACGCCGTTCTACCCGCTGCCGCAACTGTTCGGCATCGCCGGG3240               ATGATCTACGCGGTGGTCCACGTCTCGCCGACCCCGGAAATGACCGGACGGATCTTCGCC3300               AGCGCCGGCGTGGTGCTCGGCGTGGTCTCGCTGGTGGCGGTGGTGTGGATCAAGGGCGTG3360               ATGCGCAAGCCCCTCTTCGTACCCGAACCGCTCGAGACGGCCGGTGAGACTGCCCAGGGC3420               AAGTCCGTCGCCCTCGATCCCCTGCAATCCCTTCGGCCTGACGCGCCAAGGGAACAAGGA3480               GAACACAGACGATGACCGCTCAGCTCAACCCGCAGCGCGACACCCGCGACTACCAGCAAC3540               TGGACGCCGCGCACCACATCCACGCCTTCCTCGACCAGAAGGCGCTGAACCGCGAAAGGC3600               CCGCGGGTGATGGTCCGCGGCGATGGCCTGCAGCTCTGGGACAACGACGGCAAGCGCTAC3660               CTGGACGGCATGTCCGGCCTCTGGTGTACCAACCTCGGCTACGGCCGCCAGGACCTCGCC3720               GCCGCCGCCAGCCGCCAGCTGGAACAACTGCCGTACTACAACATGTTCTTCCACACCACC3780               CACCCGGCGGTGGTGGAGCTTTCCGAGATGCTCTTCAGCCTGCTGCCGGACCACTACAGC3840               CACGCGATCTACACCAACTCCGGCTCCGAGGCCAACGAGGTGCTGATCCGTACCGTGCGG3900               CGCTACTGGCAGATCCTCGGCAAGCCGCAGAAGAAGATCATGATCGGCCGCTGGAACGGC3960               TACCACGGCTCGACCCTGGGCAGCACCGCGCTCGGCGGGATGAAGTTCATGCACGAGATG4020               GGCGCATGCTGCCGGACTTCGCCCACATCGACGAACCCTACTGGTACGCCAACGGCGGCG4080               AGCTGAGCCCGGCCGAAGTTCGGTCGCCGCGCGGCGCTGCAACTGGAGGAGAAGATCCTC4140               GAACTGGGCGCGGAGAACGTCGCCGCCTTCGTCGCCGAGCCCTTCCAGGGCGCCGGTGGC4200               ATGATCTTCCCGCCGCAAAGCTATTGGCCGGAGATCCAGCGCATCTGCCGGCAGTACGAC4260               GTGCTGCTGTGCGCCGACGAAGTGATCGGCGGCTTCGGCCGCACCGGCGAATGGTTCGCC4320               CACGAACACTTTCGCTTCCAGCCGGACACCTTGTCCATCGCCAAGGGCCTGACGTCCGGC4380               TACATCCCCATGGGCGGCCTGGTACTCGGCAAGCGCATCGCCGAGGTGCTGGTGGAGCAG4440               GGCGGGGTGTTCGCCCACGGCCTGACCTATTCCGGCCACCCGGTGGCGGCGGCGGTGGCC4500               ATCGCCAACCTCAAGGCTGCGCGACGAGGGCGTGGTCACGCGGGTCAGGGAGGAGACCGG4560               CCCCTACCTGCAACGCTGCCTGCGCGAGGTCTTCGGCGACCATCCGCTGGTCGGCGAGGT4620               CCAGGGCGCCGGCTTCGTCGCCGCGCTGCAGTTCGCCGAGGACAAGGTGACCCGCAAGCG4680               CTTCGCCAACGAGAACGATCTGGCCTGGCGCTGCCGCACCATCGGCGGCTTCGAGGAGGG4740               CGTGATCATCCGCTCCACCCTCGGCCGCATGATCATGGCCCCGGCGCTGGTGGCCGGGCG4800               TGCCGAGATCGACGAACTGATCGACAAGACCCGTATCGCGGTGGATCGCACCGCGCGCGA4860               GATCGGCGTGCTCTGACGCGCCCCGGCGGCCCGGCCTCGGCCGGGTCGCCTGCGACACGG4920               AGCGTCCCCCCATAACGACGATGCGGCGCCTGGCGACCGCGCGCGGAACCGTTTCGGCCT4980               CTGGCGGCAACTGCCTAAGCAACATCACAACAATGCCAATCGGCTGTGGGAGTGTTCCAT5040               GTTCAAGTCCTTGCACCAGTACGCACACGTGTTTTCCCGGTTGTCCCTGTTCGTCCTGGC5100               GTTCGCCGCGGCGGCCCAGGCGCAGAGCCAGAGCCTGACGGTGATCTCCTTCGGCGGCGC5160               GACCAAGGCCGCCCAGGAACAGGCCTATTTCAAACCCTTCGAGCGAAGCGGCGGCGGGCA5220               GGTGGTCGCCGGCGAATACAACGGCGAAATGGCCAAGGTGAAGGCCATGGTCGACGTCGG5280               CAAGGTCAGCTGGGACGTGGTCGAGGTGGAGAGCCCCGAACTGCTCCGCGGCTGCGACGA5340               GGGGCTGTTCGAACGCCTCGACCCGGCGCGTTTCGGCGACCCCGCGCAGTTCGTCCCCGG5400               CACTTTCAGCGAGTGCGGGGTGGCCACCTACGTCTGGTCGATGGTGATGGCCTACGACTC5460               GACGAAGCTGGCCAGGGCGCCGCAGTCCTGGGCGGATTTCTGGAACGTCCGCGAGTTCCC5520               CCGGCAAGCGTGGCCTGCGCAAGGGCGCCAAGTACACCCTGGAAGTGGCGTTGCTGGCCG5580               ACGGGGTGAAGGCGGAGGACCTCTACAAGGTACTCGCCACCCCGGAGGGGGTCAGCCGCG5640               CCTTTCGCCAAGCTCGACCAGCTCAAGCCGAACATCCAGTGGTGGGAGGCCGGCGCCCAG5700               CCGCCGCAATGGCTGGCGGCCGGCGACGTGGTGATGAGCGCGGCCTACAACGGGCGCATC5760               GCCGCTGCGCAGAAGGAGGGGGTGAAACTGGCCATCGTCTGGCCCGGCAGTCTCTACGAT5820               CCGGAGTACTGGGCGGTGGTGAAGGGCACCCCGAACAAGGCGCTGGCGGAGAAATTCATC5880               GCCTTCGCCAGCCAGCCGCAGACGCAGAAGGTGTTCTCCGAGCAGATCCCCTACGGGCCG5940               GTACACAAGGGCACCCTGGCGTTGCTGCCGAAGACGGTGCAGGAGGCGCTGCCGACCCGC6000               GCCGGCCAACCTCGAAGGCGCGCGGGCGGTGGATGCCGAGTTCTGGGTGGACCACGGCGA6060               GGAGCTGGAACAGCGTTTCAATGCCTGGGCGCGCGCTGAGCGCTGCGCGTCGGCAAAAAA6120               AATGACGGGCCCCAAGTCGTCCGGGCCCGTCGGGTCAAAGCGCTGACGGGGTGATCAGCG6180               CAGCTCTTCCAACAACCCCTGCAGATACCGACAGCCCTCGGTATCCAGCGCCTGCACCGG6240               AAGGCGCGGCGCCCCCACCTCCAGGCCGGAGAGGCCCAGGCCGGCCTTGATGGTGGTCGG6300               CAGGCCCCGGCGGAGGATGAAGTCGAGCAGCGGCAACTGCCGGTAGAACAGCGCGCGGGC6360               CTTCTCCAGGTCGCCGTCGAGCACCGCCTGGTAGAGCTGGCCGTTGAGCGTCGGGATCAG6420               GTTCGGCGCGGCGCTGCACCAGCCTTTCGCGCCGGCCACGAAGGCCTCCAGCGCCAGCGC6480               GTTGCAGCCGTTGTAGAAGGGCACCCGGCCTTCGCCGAGCAGGCGCAGCTTGTGCATGCG6540               CTGGATGTCGCCGGTGCTCTCCTTGACCATGGTCACGTTGTCCACTTCGCGGACGATGCG6600               CAGGATCAGTTCCACCGACATGTCGATGCCGCTGGTGCCCGGGTTGTTGTAGAGCATCAC6660               CGGCACGCCGATGGCTTCGCCAACCGCGCGGTAGTGCTGGAACACTTCCGCCTCGTTGAG6720               CTTCCAGTAGGAGATCGGCAGGACCATCACCGCCTCGGCGCCGAGGGATTCGGCGAACTG6780               CGCGCGGCGCACGGTCTTGGCGGTGGTCAGGTCGGAGACGCTGACGATGGTCGGCACGCG6840               ATGGGCGACGGTCTTCAGGGTGAAGTCGACCACCTCGTCCCATTCCGGGTCGCTCAGGTA6900               GGCGCCTTCGCCGGTGCTGCCGAGCGGGGCGATGGCGTGCACGCCGCCGTCGATCAGGCG6960               CTCGATGGAGCGGCCGAGGGCCGGCAGGTCGAGACCGCCGTCGGCGCCGAAGGGGGGTGA7020               TGGTGTAGCCGATGATGCCGTGGATGGATGCGGACATTGGATGTACCCGTGACATTGAGT7080               GGGAAATGCCAGGACGGACCTGGTGGGAAAGGTCGTTCAGCTCAGGCAGTCGCTGTTGCG7140               CGGCAGGCAGCGCCGGGCGTAGTAGTTGAATGCGGCGCCGTGGCGCTTCGGGGTGGAGAT7200               CCAGTCGTGGGCCTCGCGCGCCAGGGCCGGCGGGATCGGCTTGATCTCTCCGGCGGCCAT7260               CGCCAGCAACTGCATCTTCGCCGCGCGCTCGAGCAGCACCGCGATCACGCAGGCCTCCTC7320               GATGCTCGCACCGGTGGCCAGCAGGCCGTGGTGGGAGAGCAGGATGGCGCGCTTGTCGCC7380               GAGGGCGGCGGAGATGATCTCGCCTTCCTCGTTGCCTACCGGCACGCCCGGCCAGTCCTT7440               GAGGAAGGCGCAGTCGTCGTATAGCGGGCAAAGGTCCATGTGCGAGACCTGCAGCGGTAC7500               TTCCAGGGTCGACAGCGCGGCGATGTGCAGCGGGTGGGTGTGGATGATGCAGTTGACGTC7560               CGGGCGGGCGCGATAGACCCAGCTGTGGAAGCGATTGGCCGGATTCGCCATGCCGTGCCC7620               GTGGAGGACGTTGAGGTCTTCGTCGACCAGCAGCAGGTTGCCGGCGCTGATCTCGTCGAA7680               GCCCAGGCCCAGTTGCTGGGTGTAGTAGGTCCCCGCCTCCGGGCCGCGCGAGGTGATCTG7740               CCCGGCGAGCCCGGAGTCGTGGCCGGCCTCGAAGAGAATCCGGCAGGTCAGGGCCAGCTT7800               TTGCCGGTCAGTCCACGTATTATCGCCGAGGCTGCTTTTCATCTGCTTCAGCGCGTGCTG7860               GATCAGTTGATCCTTGGGTAATTCCAGTGTCGTAACCATGCGAGGTTCCTTTGACGGAGC7920               GAGTCGGGGGAAACGCCAGGCAGTTGCGCGCCACGCAACGACCCGGCTGTAAATGACACG7980               GATCAAGTTATATGACACAAAGTGTCATTTAGCAAGAGAGAAGTTTCATCGCCATCGGGA8040               GAAGGCTGTCCTCAATGTCCATGCGCTTGAAATTGCTGAGAAAAAAACTCGGGGTCACGC8100               TGGAGACCCTGGCCGACAAGACCGGCCTGACCAAGAGCTACCTGTCCAAGGTCGAGCGCG8160               GGCTGAACACGCCGTCCATTGCCGCCGCGCTGAAGCTGGCGAAGGCGTTGAACGTGCAGG8220               TGGAGGAGCTGTTCTCCGAGGAAAGCGACGGTGTCGACGGCTACAGCATCGTTCGTCGCG8280               ACCAGCGCAAGTCGCTGTCCAGCGGCGACGACGGCCCGGCCTACGCCTCCCTCGTCGCAG8340               CAGATCGGCGCCCGCGCGCTGTTGCCGTTCATCGTCCACCCCCCGCGCGATTTCAGTCAC8400               TCGACGTTCAAGGAGCACCTCGGCGAAGAGTTCATCTTCGTCCATGAGGGCCAGGTCGAG8460               GTCGACTTCATGAACCAGCGGATCATCCTCGAGCGCGGCGACGCCCTGCATTTCAACGCA8520               CAGAAGCCGCACCGCATCCGCTCCCTGGGGGAGACCCAGGCGGAATTGCTGGTGGTGATC8580               CACAGCGACGAATGAGGCGACGGCTTCGGTCGATCGGATGCTTGCTAACGTTCTGTTCGA8640               TTATCGAACTGTTAATCGATTATCGGATTGTGAGCCCTCGGACCCCGGCGTAAGGTTCTC8700               GTCACGTGCCGTCCAGGCAGCGCACAACAAGACGAGACCCGACCGATGGCTGAAATCCTC8760               TCCCTGCGCGAACGGTGCGACGCTTCGTCCACGATGGCGACAGCGTCGCCCTCGAAGGCT8820               TCACTCACCTGATCCCGACGNCCGCCGGCCACGAGCTGATCCGCCAGGGCAGGAAAGACC8880               TGACGCTGATCCGCATGACTCCCGACCTGGTCTACGACCTGCTGATCGGTGCAGGCTGCG8940               CGAAGAAGCTGGTGTTCTCCTGGGGCGGCAACCCCGGTGTCGGTTCGCTGCACCGCCTGC9000               GCGACGCGGTGGAGAAGGGCTCGGCCGCAACCGCTGGAGATCGAGGAACACAGCCACGCC9060               GACCTCGCCAACGCCTATTTTGCCGGCGCCTCCGGGCTGCCCTTCGCGGTNTGCGCGCCT9120               ACGCCGGCTCCGACCTGCCGAAGGTCAACCCGCTGATCCGCAGCGTCACCTGCCCGTTCA9180               CCGGCGAAGTGCTGGCGGCGGTGCCCTCGGTGCGTCCGGACGTCAGCGTGATCCACGCGC9240               AGAAGGCCGACCGCAAGGGCAACGTGCTGCTCTGGGGCATCCTCGGCGTGCAGAAGGAAG9300               CGGCCCTGGCGGCGAAGCGCTGCATCGTCACCGTCGAGGAGATCGTCGACGAACTGGACG9360               CCCCGATGAACGCCTGCGTCCTGCCGAGCTGGGGCGCTCAGCGCCGTGTGCCTGGTGCCC9420               GGCGGCGCGCATCCGTCCTATGCCCACGGCTACTACGAGCGCGACAACCGCTTCTACCAG9480               GACTGGGACCCGATCGCCCGCGACCGCGAAAGCTT9515                                        (2) INFORMATION FOR SEQ ID NO:14:                                              (i) SEQUENCE CHARACTERISTICS:                                                  (A) LENGTH: 2471 base pairs                                                    (B) TYPE: nucleic acid                                                         (C) STRANDEDNESS: double                                                       (D) TOPOLOGY: linear                                                           (ii) MOLECULE TYPE: Genomic DNA                                                (vi) ORIGINAL SOURCE:                                                          (A) ORGANISM: Pseudomonas aeruginosa                                           (B) STRAIN: Clinical Isolate P2- 7                                             (xi) SEQUENCE DESCRIPTION: SEQ ID NO:14:                                       AAGCTTGTTCCAGGCCCTCGACCGCTGCGATCTTCTGCGGGTAGGCGGCGATGGTCTGTT60                 CGGAGTTCGCCAACTGCAGGCGACGCTGCGCCAGCTGCGCCGCCTGCACGCCGGCAAGCA120                TCAGGTCCTGATCGAGCGAGGGGTTGAAGCCGCGCACGAACTCGCTGAACTGGTCCACGC180                CGAACAGGGTGGCGATGAGCTGGCGCTGATCGCTCGGGGTCCGCGCGGCGATTCGGGCGA240                AATCGTCGAGGCGGTTCTTCTCGATGAAGCAGAAGCGATACTCAGCTTCGTCGGGCTGGA300                CGGCCTGCGCCTCGCCCGCNGCCGTAGACGACAGGACTGGCGCGATGTGGCGGCGCAGGC360                GAGCGTTGTTGCAGTACGTCCGCTGGTCGACCGCTTGGCCTGCGCTTCGCTGATCGAACC420                GAGCATCGCCACTTCCAAGGCTTCGCAGAAGCTGCTCTTGCCGGTGCCGTTGGCACGTNA480                GACCAAGGTGATGTCATGGCTGAGGTCGAACGTCTCCTGCCGCATGAATCCTCGAAACGG540                CCCGACTTCGAGCTGGTGCAGTCGCCCGAGCGCCGGCCCGTTTTCGGGGCCGCGCGCGTC600                CCCGTCGTAGGCGACAGGCATCTGCGCCAAGATGCGCGATGGCCAGCGGCGCCAAGCCGC660                GTGGGAGCGCCCCCCGGCGTGCAGCACCGACCTCGGCCAGTGGCTGCAGGTGATCGAGCA720                CCAGGGTGCGCCAGCCGGCGCACCGTTTCGTCGTGCACGTGCCGCTGCGTCAAGTGCGCC780                AGGAACCGGTGGTACTCCGAACGTATGCTTGCCACAGCGACCCCTCACTTGGTCAACCAC840                TGACCGTAAGCCTCCACATCGATCATGGGGACCGTTCCACTGAACTGAAGCTGCGCGATC900                AGCTTGAAAAGAAACGCGGTCGCCGGCTTGTTTTCGTTGGTGTAGCTGTACGCGCCGCTG960                GCTTGGTCATAGAAAAAGTGCCCGTGGGCGGCAACGCATCCGATGTCCAGACGCCCCTCG1020               GTGAGGTTTGCGTTCAGCGCCTTGTCCATGGATGGGCCCAATGCAGGACTCCATTCGCTC1080               TCGAAGGTGAGCAAGCCACCCAGAATCGGAATCAACGCTTCGCTGGGTAGGTCCCGCCAG1140               CGTGCGGGATCGGCAGGCTCGTGCGGTGCAGCCTGCGCACACTGGCGACCTTCTCCTGGC1200               ATAGCCACAAGCCCCGCGTCAGCCGTCTGCTTGGCCTCGAACACGGCGTACACGCTTTCG1260               GCTGGAATGATCGTCTCGTTCTCGTAGGTGAAGATAAAAGGCGAATATTGCCGATCAAAC1320               ACCACCACATCGATCTGCTGGCTGAAGTTCCCCAGGCTGTCCACCACATGCGCCTTCGCC1380               GCCTGGTACCGTTTGGGCAGATAGGTATCCAGCATGTCGATCCAGACGTTCTCGCTCGCA1440               TCCCCCTTCGTACCCGGGTGACCGAAGGTCTTGCGTACTACGGACAAGCGCTGCTGGATG1500               TCTTCATGCAGGGACGACAGGAGCTGGGAAAGCGACCACTGGGACATGCTGTACCTCGAT1560               GGGACGTGTATGGAAGCCGATGGAATCAGGACAGTGGGAACTTGGGGCCAAACAGTGCGC1620               GCCAGGGCGAAGCGCTTCGATATTGCGACCACGACGCGTGTGGTCGATGGCGATGCTTGC1680               GTCCTGGCTCGCCTGGAACAGCAGCTGCTNGCGNGCGCTGCTTGCGCGCGGCATCCATAT1740               CGTTGCTGATCGCCGGGCCAAGTCCGGCGGGATCCGGCCACTCGTCATGAACACGATCGG1800               CAAGCGTGGCAAAGAACGACTGGATCTCGCGATCGAACGATCCTCCCCAGCCGCCGTAAA1860               GACACTCAAGGGCCATTACCTCGATCAGGAACGAGGGCTTCACCGGCTTCTGATCGCCGT1920               GCTTGGGATTGTTGTTCCAGTACTTCACCATGCGCACGAGACCTTTCCACTCATTGCCAT1980               AGGCTTGGTGCGCTGCGGTCGCCTTGTCCTTATGGATCTCCGGGTCCGTCTTGATCCACT2040               TTCCGGACGCCGTATCGGGGATCTCATACTGGTCGCCGGTGTCGAATGCGGGCACCGCAT2100               CCACGCTGACCACCCGGTAGTCCGTGTTGTCCTCCGCGTCGATGTGAACACCGAAATCCA2160               CGTTGATCGAGNGCGCCTGTTTGCGCACGGCCGCCGAACCGTATTTCTCCACCAATGCAG2220               AGTGGAAATCATCCAGCACTACCGATGCGGCCTTGCCGTGGTAATGCTTCTCCGAGTCCT2280               TCAGCACGAAGAAGATGTCGATATCCTTGAGCGGCTTCGTCTTCGTGTATCGAGCATAGG2340               ACCCGGTCAGGAACTGCGCGCAATGCCGAACTTGGTCTGCAGGTAGTCCCGCACTTCGTT2400               CTGGCGTTGCGAGGCATTCTTCTGCTCGCGTTCGTTGAGTTCCAGACGCGACTTGAACTT2460               GCGAAAAGCTT2471                                                                (2) INFORMATION FOR SEQ ID NO:15:                                              (i) SEQUENCE CHARACTERISTICS:                                                  (A) LENGTH: 5247 base pairs                                                    (B) TYPE: nucleic acid                                                         (C) STRANDEDNESS: double                                                       (D) TOPOLOGY: linear                                                           (ii) MOLECULE TYPE: Genomic DNA                                                (vi) ORIGINAL SOURCE:                                                          (A) ORGANISM: Pseudomonas aeruginosa                                           (B) STRAIN: Clinical Isolate P2- 17                                            (xi) SEQUENCE DESCRIPTION: SEQ ID NO:15:                                       AAGCTTCGAGGGGGCTGGGCGAGGATCGACCGGCCCCGCTCGTGTCGGAAGGGAAGGCCA60                 GGGCTGGCCTGCCCGTTCGGCGCTTCGGCAGGCTGGCGCAGAACGATGCAAGGTCGTTCG120                GGTCAGCATCAGGGATGAAATGACTGACAGGAGTCGGGATGCTGCGTTACGTCGTGGGTT180                TTCTCGCGTTCACCGTGCTGGCGGCCTATCTGTTGCTGGGGGTTTCCCAGCACGCCTTCC240                TGCCGTGACCGGTCGGCATGGCGGCTTCAGCTGCGTTGCGGAAGAGGCTGTGGCGGCCGT300                GCGGGATGCCGGTTTTCGGCTTGCCGTGCCTTGCGTTGCAGGCGTCGCGCCGACGCGGCA360                CGCCAGGGAAGGCCCACAGGGTGACGCCGGCGAGGCCCAGCCAGGCGACGATCAGCAATG420                TGACGAAGGATTCGGGAGTCATGGTTCGTCCTCCTCTTACCCAAGGATAGACCCTGCGGG480                AAGGGGAATTACTGCAATCGGTCTTCGACCATGGTCTGAAACGCGGTCACTCGGGGCCGG540                CGCCGACCAGGGCCAGGCAGCCGGTGAGGCTGGTCAGCAGGGGCAGGGCGAGCAGGAAAG600                CCAGCCAGATGGCCTCCATGCGCAACAGCGTGGCGCCGAGGAACAGCGCGACCAGGAGGA660                TGGTCATGAGCAGGGCGGTCCAGCCGAAGTACATGGCGAAGTTGTCGATGCCCAGGCCGA720                TGCCCCAGCCCAGCAGCAGGGCCCATACCCCGGCCAGAGCCAGGCCGAGGGCCAGCATGC780                TCGCCAGGGTCCGGGCGGACGGGGCATGCAGCGGGTGGTTGCGGAATAGCTCGTAGAAGA840                TCGGCGTATTCATCGGCGTCACCTCCGCAGGGGAACTTCCAGCCTAGTCCAGCGGGCGAG900                ACGGCCCTAGACCTATTTGTCATTACGAGGCGTGACCTCAGGCCGTTAACATCCATCTTT960                TTCCAGGCGATGCCGTGCATCGGGCTGCGGGCCCGCTCACCGTTCGTCGCGCTGAGTCGA1020               AAAAGAAACCGAAAGGGTTGCGTGCATGAGTTGGCGAACTCGCCTCGTTCGAGGTGGATG1080               GGTATCAACTGGTCTATCAGGACCTGGGTGAAGGCACGCCGGTGCTACTGGTCCACGGTT1140               CGCTGTGCGACTACCGCTACTGGCAATGGCAGTTGCGCAGCTCGGCAAGCACCACCGGCT1200               GATCGTGCCGAGCCTGCGTCACTACTACCCCGAGCGCTGGGACGGGCAGGGTGCGGACTT1260               CACCAGCGCCCGCCACGTCGCCGACCTGCTGGCGCTGGTCGAGCGGCTCGGCGAGCCGGT1320               ACACCTGCTCGGCCATTCCCGTGGCGGCAACCTGGCGTTGCGCCTGGCGCTGGCCGCTCC1380               GGACGCCCTGCGTTCGCTGAGCCTGGCCGATTCCCGGCGGCGACTATGCCGCCGAGGTCT1440               ACGCCCACGCCGGCCTGCCTGCGCCCGAGGAACCATTGGAACGCAACCAGTTCCGGCGCC1500               AGGCGCTCGAATTGATCCGTGGCGGCGAGGCGGAACGGGGACTGGAACTGTTCGTCGATA1560               CGGTGAGCGGCGCCGGGGTATGGAAACGCTCGTCGGCGACGTTCCGCCGAATGACGCTGG1620               ACAACGCCATGACCCTGGTCGGGCAGGTGGCCGACCAGCCGCCGGCGCTGGCGCTGTCGG1680               AACTGCGCTCGATCGACCTGCCGAGCCTGATCCTCAATGGCGAACGCAGCCCGCTGCCAT1740               TCCCGGCCACCGCCGAGGCGCTGGCGGCGGCCCTGCCGCGCGCCGAGCTGCAACGCATCC1800               AGGGCGCGTCCCATGGCCTCAATGCCACCCGTCCGGCGGCTTTCAACCGGTCGGTGCTGG1860               AGTTCCTGGCGCGCGTCGATGGCGTTGCGCCGGACGTGGAAACGTCCTGAAGCGAGGCCG1920               GGCGAACTGACCGCTCGTCAGCTCGCCGCGGATGCTTTACCATGCGTTCGCGCCGGATCA1980               GCTCCGGCGTTTTTCGTCAGTATCCATTCCCAGTGATCTCCGTCCGCGCGCTTCGGCGCA2040               GGGGTGCCGCAAGGCGCCTGCCACTGTGAGGCAGGCCGGCCCGGCGGGCGACGCTTACTG2100               GCACATCCCAACCCACGTGGCCTTTGGTAGGGTCACCACTAGAGAGAGCGCCATGCCCAT2160               CATTACTCTTCCCGACGGCAGTCAACGTTCCTTCGATCACCCGGTCTCCGTGGCCGAGGT2220               GGCCCAATCCATCGGCGCAGGCCTGGCCAAGGCGACCCTCGCCGGCAAGGTCGACGGCCG2280               CCTGGTCGACGCCTGCGACACCATCGATCGCGACGCGACCCTGCAGATCATCACGCCCAA2340               GGACGAGGAAGGACTGGAGATCATCCGCCACTCCTGCGCCCACCTGGTCGGCCATGCGGT2400               CAAGCAGCTCTATCCGACCGCGAAGATGGTCATCGGCCCGGTGATCGAGGAAGGCTTCTA2460               CTACGACATCTTCTTCGAGCGCCCCTTCACCCCCGAGGACATGGCGGCGATCCAGCAGGC2520               ATGCGCGAGCTGATCGACAAGGACTACGACGTGATCAAGAAGATGACCCCGCGCGCCGAG2580               GTCATCGAGCTGTTCAAGTCCCGTGGCGAAGACTAACAAGCTGCGCCTGATCGACGACAT2640               GCCGGACGAGAAGGCCATGGGCCTGTACTTCCATGAGGAGTACGTGGACATGTGCCGCGG2700               CCCGCACGTGCCGAACACTCGCTTCCTCAAGGCGTTCCAGCTGACCAAGATTTCCGGCGC2760               CTACTGGCGCGGCGACTCGAAGAACGAGCAGTTGCAACGCATCTACGGCACCGCCTGGGC2820               CGACAAGAAGCAACTGGCGGCCTACATCCAGCGCATCGAAGAGGCCGAGAAGCGCGACCA2880               TCGCCGCATCGGCAAGCAGCTCGACCTGTTCCACCTGCAGGAAGAAGCGCCGGGCATGGT2940               GTTCTGGCACCCGAATGCTGGAGCGTCTACCAGGTGCTCGAGCAGTACATGCGCAAGGTC3000               CAGCGCGACCATGGCTATGTCGAAGTGCGTACCCCGCAGGTGGTCGACCGCATCCTCTGG3060               GAGCGTTCGGGCCACTGGTCGAACTACGCCGAGAACATGTTCACCACCTCCTCGGAAAGC3120               CGCGACTACGCGGTCAAGCCGATGAACTGCCCGTGCCACGTGCAGATCTTCAACCAGGGC3180               CTGAAGTCCTACCGCGACCTGCCNTGCGCCTCGCCGAGTTCGGCGCCTGCCACCGCAACG3240               AGCCGTCCGGCGCGCTGCACGGATCATGCGGTACGCGGCTTTACCCAGGACGACGCGCAT3300               ATCTTCTGCACCGAAGAGCAGGTGAAGAAGGAAGCGGCCGATTTCATCAAGCTGACTTGC3360               AGGTCTACCGCGACTTCGTTTCACCGACATCGCCATGAAGCTGTCGACCCGTCCGGCCAA3420               GCGCGTCGGTTCCGACGAGCTGTGGGATCCCGAAGGCGCGCTGGCCGATGCGCTGAACGA3480               ATCCGGCCTGGCCTGGGAATACCAGCCGGGCGAGGGCGCGTTCTACGGGCCGAAGATCGA3540               GTTCACCCTGAAGGACTGCCTCGGCCGTAACTGGCAGTGCGGCACCCTGCAGTACGACCC3600               GAACCTGCCGGAGCGCCTGGACGCCAGCTACATCGCCGAGGACAACAACCGCAAGCGCCC3660               GGTGATGCTGCACCGTGCGATCCTCGGGTCCTTCGAGCGCTTCATCGGCATGCTCATCGA3720               GCACTACGCCGGAGCCTTCCCGGCCTGCTGGCGCCGACCCAGGCAGTGGTGATGAACATC3780               ACCGACAAGCAGGCCGATTTCGCCGCCGAGGTGGTGCGGATCCTCGGGGAAAGCGGATTC3840               CGTGCCAAGTCCGACTTGAGAAACGAGAAGATCGGCTTTAAAATCCGCGAGCATACTTTG3900               CTCAAGGTTCCCTATCTCTTGGTTATTGGAGATCGGGAAGTTGAATCGAAGGCCGTCGCG3960               GTGCGTACGCGCGAAGGGGAAGACCTGGGCTCCATGCCCGTCACCCAGTTCGCTGAGCTG4020               TTGGCACAGGCGGTTTCCCGGCGTGGTCGCCAAGACTCGGAGTAATCATTATTAAGCGTG4080               AAATGAGACAGGATAAGCGAGCTCAACCGAAACCCCCGATCAACGAGAACATCTCGGCTC4140               GTGAGGTACGGTTGATTGGAGCTGATGGCCAGCAGGTTGGTGTTGTTTCGATCGATGAGG4200               CGATCCGCCTAGCCGAAGAGGCGAAGCTGGACCTGGTTGAGATTTCGGCCGACGCGGTGC4260               CTCCTGTCTGCCGCATCATGGACTACGGCAAGCACCTGTTCGAGAAGAAGAAGCAGGCTG4320               CGGTCGCCAAGAAGAACCAGAAGCAGGCGCAGGTCAAAGAAATCAAGTTTCGTCCAGGGA4380               CGGAAGAAGGGGATTACCAGGTAAAACTACGCAACCTGGTACGTTTCCTTAGTGAAGGGG4440               ACAAGGCCAAGGTATCCCTGCGATTCCGCGGCCGTGAGATGGCTCACCAGGAGCTGGGGA4500               TGGAGCTGTTGAAGCGGGTCGAAGCCGACCTCGTGGAGTACGGCACCGTCGAGCAGCATC4560               CTAAGCTGGAAGGACGCCAGCTGATGATGGTCATCGCTCCCAAGAAGAAAAAGTAACCAC4620               CAGGGCACTGGCAGGCCTTGCGGTTATGCGTAATCACTCAATGCGGAGTATCCGAACATG4680               CCAAAGATGAAGACCAAAAAGTGGGCGCGGCCAAGCGCTTCAAGAAGACTGCTGGTGGCC4740               TCAAGCACAAGCACGCCTTCAAGAGCCACATCCTGACCAAGATGACCACCAAGCGTAAGC4800               GTCAACTGCGCGGCACCTCGATGCTGAACAAGTCTGACGTTGCGCGCGTAGAACGCTCCC4860               TGCGTCTGCGCTGATTATTAAGGTAGAGGATTAATTCATGGCTCGTGTTAAGCGTGGCGT4920               TATCGCCCGTCGTCGTCACAAGAAAATTCTGAAGCTCGCCAAGGGCTACTACGGTGCACG4980               CTCGCGCGTGTTCCGCGTTGCCAAGCAGGCGGTGATCAAGGCTGGCCAATACGCCTACCG5040               TGACCGTCGTCAGCGCAAGCGTCAGTTCCGCGCACTGTGGATCGCCCGTATCAACGCTGG5100               TGCTCGTCAGAACGGTCTGTCCTACAGCCGCCTGATCGCCGGCCTGAAAAAGGCGGCCAT5160               CGAGATCGACCGTAAGGTCCTGGCCGATCTGGCAGTGAACGAAAAAGCGGCGTTTACCGC5220               GATTGTCGAGAAAGCGAAGGCAAGCTT5247                                                (2) INFORMATION FOR SEQ ID NO:16:                                              (i) SEQUENCE CHARACTERISTICS:                                                  (A) LENGTH: 2812 base pairs                                                    (B) TYPE: nucleic acid                                                         (C) STRANDEDNESS: double                                                       (D) TOPOLOGY: linear                                                           (ii) MOLECULE TYPE: Genomic DNA                                                (vi) ORIGINAL SOURCE:                                                          (A) ORGANISM: Pseudomonas aeruginosa                                           (B) STRAIN: Clinical Isolate P4- 5                                             (xi) SEQUENCE DESCRIPTION: SEQ ID NO:16:                                       AAGCTTTGGTGATCTTAACGTGACAAGCTCCTTAGAAAAATTTTATGAGTTTATTAGCGG60                 GGTCTTTCTTGATCCGACTGTACCAAGACTTTCAACTCGTAAAATACGCAAGCACAAAAG120                CACTGAAATGCACTCTGCACGTTTGTCGCCGTCCACGGTAGCGGCATCCCTCAATCACAC180                CGAAGCGGTGAATCTTTCTACCTATGCAGAGGCAACACCTGAACAGCAGCAATCCGAGTT240                CAGCCTGTTTTGGGATGCAATACGCCACGCTGCTCATGTTGTGCGTGAGCGAAGCCGCAA300                GGCTGTAGCAAGTAGTGTCGCAATAGCGGCGGGTCACTGCGAGGATTTCAATAAGCCGAC360                GTCTGCCACTGATGTGGGATTGATTATAGAGCCGAACTGCCGCACCCAATATGGTTGTTT420                GTACTGCGAAAACTATTTATGTCACGGCGATGAGGAGGATCTGCATAAAATTCTGAGTTT480                GCAATACGTGGTCAATGCCGTGCGTAAATCGGCCCCCGATGCAGCGCATACTGAGGCACT540                TTTCAAAGAGTTATCTATCCGGATCGAGTTTATAGTCGATGCTCTTAGTGAGCGCTCTAG600                CTCGGTGAAACAGACAGTCGAAAAGGTTAAAGCTAAGGTGTTTGAATACGGCGAGTTAAC660                TAAGTTTTGGGAAGTCCGGTTGGGTCGCTATGAAAAAATGGGGATCGTATTTTGAGTGCT720                GCTGTTCAGTCGATAGGTAGTCTTTTTTCTAGCGGCCAGTTTCCAGTCACCAGCCAGCCA780                GATAGTGCGGCTCAGCTGTATGGGAAGCCCGCGTCGGATTTTGTTATCTGTCGCACTGAG840                TATGGCAATGCAACGGCAGTGTACGGCGAGTCTGTATGGGACTTTAACCCGTACAGGCTG900                AGTGCAAAAAAAATTGGCCGAATACGCTTCGATATGGTGTTCGGTGATTATGGTCATGAT960                CAGCAAGCGCTGATCGAAGAAGCCAAATATCTTCTGTATTGTCTTATTTATTTCGCTGGC1020               GGTGGGCGGATTGGTAAGCTGAGTGCATCTACGATTATTTCATATTGGGTTGTGCTGCGC1080               ATCGCTATGAAGTTCTGCTATGCGCAGAAAAAGAAGTCAATGGTTGGTGTGCTGTCCTTG1140               CAGCAGCTTTTTACCGTGCCTGTTTATCTAGCGGCTTTTGTTAGTGAAAGTAATTTTGAC1200               AAGACGGTTCTTAGTGGGATATTGCACGGATTGATTAGTGTGGGCGAGGAACGCCTAGGG1260               TATGTTGTGCTGAATCCAAGAGTTTTTGATTTGAGAAGACCTGATTCTAAACAGCATTCC1320               GGTAATTCCGACACGCCTTTATTTGAATTTAATAATATTGTGGCGACCTGCTCGATCATC1380               TTACTTGGGTGTTGGGAATATTGATTCATTTATATCGTGCTTTGCTGATGAGTATTTCGG1440               TCTTACTCCGCACCGTCAAAAATCTTTGGGGGTTGGTGGTAAGTCGCGCTATCGCCCCGG1500               TATTCAGCAAGCAATAGAGGAATATGGTCTGGCTGCGGTTTTTGTCGGTGAGTTTGCCTG1560               TTCCGAAAAGAGAAAGCTGCAGCGAGTCCTTCTCAAGATGCAGTATGTGGTGAGAATGGT1620               GATACACCTATATACCGGCATGCGTGATCAAGAGGTGATGCGTATGTCTTATAACTGCTT1680               ATCTGATCAAGTCGTGAGATGTTCAGTGGTTGATGATCAAGGTTTTATGCGCGATCAACC1740               GCAATCAGTACACATATTATCGACTACCACGAAGTTTAGCGGTTACAAGAAAGAAAGCGC1800               ATGGTTCGCGGCAGGCGAAGTCGTCAAGGCGGTCGAGGTTGGCCAGGCGATTTGTCGTGG1860               TTTAGCCCGGCTCTATAGGATTGAACTGGATGATCGTTGTCCGCTATTCATCAATCCGTC1920               CGTCCTGTGTAAAACGAAGAATTGTGCAGAAGTTGGTGTAACAGACTTTACATTGAGAGC1980               AACGATGGCAGTGCTTTGAAATCCTTATCGATTCAATCAGAGGATTTACAAGAGTTGGCT2040               CAGAGCGACCCTTCTCGTGACTTTTACAATGAGCCAGATTTTGCAGTAGGCCAGCCCTGG2100               CCGCTGACTAGCCATCAATTCCGACGTTCGTTGGCCTTCTATGGAAGCAGTAGCGGCTTT2160               CTCTCGTTACCGACTCTGCGAGCGCAGTTCAAGCATATGACCCATTCAGATGGCGCGCTA2220               TTATGCGAATGGCTTTGATAACTTGCGCACCATTTTTGGCTACTATGACGAGAAGAAAAT2280               AGACTTCGTGCTACCATATAACCACTTTGCTTTCGAGTTCCAGATGGCCATGCCGATGTC2340               GGTGGCCAATCAGTTGATTGCAGATCTGCTGTTCAAAGAAGAACCGCTGTTTGGTGGCAC2400               CGGTTCATACATGCAGAGGCAGAAAGAACGTGTTGAAGCTGGCGAGATAAAGATTGAAGA2460               TATTCGTGCCGATACAGAGCTTCGGGTGAAGAACGGTGCAATTAGCTATCGGCCAACGCT2520               ACTCGGTGGTTGCACCAAGGTGGGCCGCTGCGATTCCTTCATGCTCGGTGACTATACTGA2580               ATGTTTGTCCTGCGAGGGTGCGATTATCAAGCCCTCCAGGTTAAGTGCGGCCATTGAGGA2640               TGCGAAAAACGAGTTGTCAAACTACGCAGAAGACTCAGGCGAATATCAAATTGTGAAGGG2700               CGATATTGAGCGCCTAATGGTTTTCAAGACTCGCCTGATCGACACTGTGGAGCTTTAGTC2760               ATGAAGTCTGGTGAAGGAATAAGCAAGGGGGTTGGTGCCTGTCAGGAAGCTT2812                       (2) INFORMATION FOR SEQ ID NO:17:                                              (i) SEQUENCE CHARACTERISTICS:                                                  (A) LENGTH: 3615 base pairs                                                    (B) TYPE: nucleic acid                                                         (C) STRANDEDNESS: double                                                       (D) TOPOLOGY: linear                                                           (ii) MOLECULE TYPE: Genomic DNA                                                (vi) ORIGINAL SOURCE:                                                          (A) ORGANISM: Escherichia coli                                                 (B) STRAIN: Clinical Isolate EC- 24                                            (xi) SEQUENCE DESCRIPTION: SEQ ID NO:17:                                       AAGCTTTTCTTGCGTGTTCTTGTGAGGCTTCCTTCGCCATTATCATCACGATCCACATAA60                 ATAAAGCCGTAGCGCTTAGACATTTGTGAATGAGATGCACTGACTAAATCAATTGGCCCC120                CAACTGGTGTACCCCATAATATCCACACCATCGGCAATCGCTTCATTTACCTGTACCAGG180                TGATCGTTTAAATAGGCAATTCGATAATCGTCCTGTATCGAACCATCCGCTTCAACGCTG240                TCTTTTGCGCCTAATCCGTTCTCGACAATAAATAACGGTTTTTGATAACGATCCCAAAGC300                GTATTTAACAGAACCCGTAATCCAACCGGATCAATTTGCCACCCCCACTCTGAACTTTTC360                AGATGCGGATTGGGGATCATATTCAGTATGTTGCCCTGCGCATTTTTATTAATGCTTTCG420                TCGTGGGAACACAACCAGTCATGTATAACTAAAGAGATGAATCGACGGTATGTTTTAAAT480                CTCTGCGTCACTTTCAGTCATCTCAATGGTGATATTGTGGTCGCGGAAGAAACGCTGCAT540                ATAGCCGGGATACTGGCCACGCGCCTGAACATCACCAAAGAACATCCAGCGCCGGTTCTC600                TTCCATGGCCTGCAACATATCCTGTGGCTGGCAGGTGAGGGGGTAAACCAGCCCACCGAG660                AAGCATATTGCCGATTTTCGCTTCGGGGAGCAGGCTATGACAGGCTTTAACTGCCCGCGC720                ACTGGCAACCAGTTGATGGTGGATAGCCTGATAAACTTCCGCCTCGCCACTCTCTTCTGC780                CAGCCCCACGCCCGTGAATGGCGCGTGTAACGACATGTTGATTTCATTAAACGTCAGCCA840                TAACGCCACTTTATGTTGGTAGCGAGTAAAGACCGTGCGGGCGTAATGTTCGAAGTGATC900                GATGACCGCTCGATTAGCCAACCGCCGTAGTTTTTCACCAGCCCATATGGCATTTCGTAA960                TGGGATAACGTTACCAGCGGCTTGATCCCCGCCTGCGCCATTTCATCAAACAGCCGATCG1020               TAAAACGCTAACCCCGCTTCATTCGGTTCGACTTCGTCGCCCTGAGGGAAAATTCGCGCC1080               CAGGCAATGGAAATACGCAGACAGGTGAAGCCCATCTCGGCAAATAACGCGATATCTTCC1140               GGGTAACGGTGATAAAAATCGATGGCGACATCTTTGATATTCTCTTTCCCCAGGATGCGC1200               GGTTCCATTTTTCCCATTACGCATGAGGCTGTAAATCTGAGGTCGAGATCCCTTTGCCAT1260               CTTCCTGCCAGGCACCTTCCACCTGATTGGCAGCTGTTGCGGCACCCCAAAGAAATGTTT1320               CTGGAAATGCTTTCATAATTAACTCCTTTTATCGTTAGCGAATGATGGATAACAGCGGTT1380               CACCTGCGCTTATCTGCGCCGTGCCGTGGGGTAATACGTCCGTAAAATCATCGCTATTAC1440               TGATTAATACCGGCGTCGTCAGATCAAATCCGGCCTCGCGAATAGCAGGGATATCAAAAG1500               AAATCAGCCGATCGCCTGTATTGACCTTGTCACCCACGTTGACGTGAGCGGAAAAGAATT1560               TGCCGTCCAGTTTTACGGTGTCGATACCGACATGAATCAGGATCTCCACACCATCATCTG1620               ACTCAATGCCAATGGCGTGTAATGTGGCGAACAACGAAGCAATTCGACCCGCAACCGGAG1680               AACGCACTTCACCAACCGAGGGCAGAATGGCAATACCTTTACCCAACAGGCCACTGGCAA1740               ACGTGGTATCAGCGACGTGAATGAGCGACACAATCTCTCCCGTCATCGGTGAACAGATAC1800               CGCCCTGCTCAGGTGGTGTAATAACCTCTGGTGTTTTCTCTTCGGGGCACCCTGCGCTGG1860               CTGACGTTTAGCGGTGATGAAATGAAGCATCACCGTACCGACAAATGCGCAACCGATGGC1920               AATGACACCGCCAATAACGCTGGCCCAGACGGTGAAATCAATTCCCGTTGACGGGATGGT1980               TTGCATGAAGGTGAAAATACTTGGCAAACCAAAGGAGTAGACTTTCGTTTGCGCGTAGCC2040               AATAATGGTGGCCCCCAAAGCCCCACTGATACAGGCGATAACAAAGGGGTACTTACGCGG2100               CAGGTTGACGCCATATACCGCTGGTTCGGTGATACCAAACAGACTCGTCAACGCCGCTGA2160               TCCCGCCACCACTTTTTTCTGCGCATCGCGTTCGCAGAGGAAGACGCCGAGCGCCGCCCC2220               GACCTGCGCCATAATGGCGGGCATTAACAGCGGGATCATGGTGTCGTAGCCCAGCACGGT2280               GAAGTTATTGATACACACCGGCACCAGGCCCCAGTGCAGTCCGAACATGACGAAGATTTG2340               CCAGAAGCCGCCCATTACCGCGCCCGCAAATGCAGGAACCGCCTGATAAAGCCAGAGATA2400               ACCGGCGGCAATCAGTTCGCTTATCCAGGTTGATAGCGGCCCCACCAGCAGAAAGGTGAC2460               GGGTGTGATAACCATCAGACATAGCAATGGTGTGAAGAAATTTTTGATTGCCGACGGTAA2520               CCACGCATTAAGTCGGCGTTCCAGAATGCTGCACAACCAGGCAGAAAAAATAATGGGAAT2580               AACCGATGACGAGTAATTCAACAATGTGACCGGAATACCCAGGAAATCCAGCCCCAGCGC2640               ATCCGCTTTTGCGCGTTCTCGAAAAGCAGTACAGAATTAATGGATGCACTAACGCTCCAC2700               CAATCACCATGGCAGTAAATGGATTATCGCCGAAGCGTTTCCCCGCGGTGTATCCCAGGA2760               TTATCGGGAAGAACCAAAACAAGGCATCACTGGCGCTGAATAAAATTAAATAAGTACCAC2820               TTTGTTCGGGCGTCCACTGAAAAGTGAGCGCCAGAGCCAGCATACCTTTCAAGATCCCCG2880               GTTGCCCGCCATCAAACCGATACAGAGGCGTAAAAATACCTGAAATAACATAAACAAAGC2940               GGTTTAGACAGATTACCTTTATCATACATTTTCCGGTGCCTGTTGCGCTTTTTCGTCAAG3000               GCCTGCCACACTGTTAACCGCCAGGAAGACATCGGCCACATGGTTACCTATGACCACCTG3060               AAACTGGCCACCGCTTTCCACCACCATAATAATACCGGGGGTCTTTTTCAGTACCTCTGC3120               TTGCGCTTTGCTTTCATCCTTTAATTTAAAAACGTAAATCGCGTTGCGCAATGCATCAGA3180               CTCACAATGTTATCTGCGCCCCCGACTCCTGCGACTATTTTTCTGGCTAACTCCGTCATA3240               ACTTGCCCTCTACGCTTTGCGGCAAAACTCCAAAAAAAAACCTGAAAAAAACGGCCTGAC3300               GTGAATCAAGCAATTTTTTTCAGGTTTTGCCCGCTTAGTGCGGTAACAATCCTTTACTCA3360               GTAATAATATTTCAGTGTTCTTTGCGCACGCGCTCTATATTTATGGCTAAAAACATAATC3420               TCTGCGGGTGAAATTTTACGTTGATACTGCAAACCAATAAAAATGGCGATCCGTTCCGCA3480               CATTGCCATGCTTGCGGGTAATTTTGTTTTACTGCTTGTTGTAATGATTCATCACTATCG3540               TTAATTGAAGCATGTTCAAGAATACGCCAGGATAAAAACTTCAGATGTGTAACCAGTCGC3600               TGATAACTCAAGCTT3615                                                            (2) INFORMATION FOR SEQ ID NO:18:                                              (i) SEQUENCE CHARACTERISTICS:                                                  (A) LENGTH: 4954 base pairs                                                    (B) TYPE: nucleic acid                                                         (C) STRANDEDNESS: double                                                       (D) TOPOLOGY: linear                                                           (ii) MOLECULE TYPE: Genomic DNA                                                (vi) ORIGINAL SOURCE:                                                          (A) ORGANISM: Escherichia coli                                                 (B) STRAIN: Clinical Isolate EC- 34                                            (xi) SEQUENCE DESCRIPTION: SEQ ID NO:18:                                       AAGCTTAACCGCTCTCATCTGTTGACCGCACGGCATAGCTATATTCTGCCGGTCCTGGGA60                 CGTAGCGAGATTGACATGCAAAAAAACGGTGCGCAGGCGGTAACCGTTGAGGATTCAATG120                TCGATGATTCATGCCTCGCGTGGCGTGTTAAAACCCGCCGGTGTAATGCTGAAATCAGAG180                TGTGCAGTGGTCGCGGGAATCGCGCAGGCAGCACTACCCCAGAGCGTGGTAGCCTGGGAG240                TATCTGGTGGAAGATTATGATCGCATTCGCAATGACATTGAAGCTGTGCTGCCAGAGTTC300                GCCGACTATAACCAGCGCATCCGTCATCCCGGTGGTTTTCACCTGATAAATGCAGCTGCT360                GAAAGGCGCTGGATGACGCCGTCAGGTAAGGCTAATTTCATTACCAGCAAAGGGCTGTTA420                GAAGATCCCTCTTCAGCGTTTAACAGTAAGCTGGTCATGGCGACAGTACGCAGCCACGAT480                CAGTACAACACGACGATTTATGGTATGGATGATCGCTATCGAGGGGTATTCGGTCAACGA540                GATGTGGTCTTTATGAGTGCTAAACAAGCTAAAATTTGCCGTGTAAAAAACGGCGAAAGA600                GTTAATCTTATTGCGCTTACGCCAGACGGTAAGCGCAGTCACGCCGCATGGATAGATTAA660                AAGTGGTCATTTACCCTATGGCTGACCGCTCACTGGTGACCTATTTTCCAGAATCGAATC720                ACATGCTAACACTTGATAACCACGATCCATTAAGTGGCATTCCTGGCTATAAAAGTATTC780                CGCTTGAATTAGAACCATCAAATTAATGTCTCTTCTCATTTCTTCTGCTGTCATCCGCAC840                AGCAGAAGAATTCCTCATTGACTATTATTTCGCAATTTGCTCACATGGATTAAATTAAAC900                TACATACTATAAGATATAAACTTCTGCCTACAGCTGTAAGAAACTCCGCTCAGTACTGAA960                GCACCAGTCCTATTTCCTCTTTTCTCCAGCCTGTTATATTAAGCATACTGATTAACGATT1020               TTTAACGTTATCCGCTAAATAAACATATTTGAAATGCATGCGACCACAGTGAAAAACAAA1080               ATCACGCAAAGAGACAACTATAAAGAAATCATGTCTGCAATTGTGGGTGTCTTATTACTG1140               ACACTTACGTGATAGCCATTTTTTCGGCAATTGATCAGCTGAGTATTTCAGAAATGGGTC1200               GCATTGCAAGAGATCTTACACATTTCATTATCAATAGTTTGCAAGGCTGTAAACAAACAG1260               CAAATTATAAATATGAAATGTTAAAAAAGTATCGATAAAAACTTTATTGTTTTAAGGAGA1320               TAAAATGTCGCTCGTTTGTTCTGTTATATTTATTCATCATGCCTTCAACGCTAACATTTT1380               AGATAAAGATTACGCCTTCTCTGACGGCGAGATCCTGATGGTAGATAACGCTGTTCGTAC1440               GCATTTTGAACCTTATGAGCGGCATTTTAAAGAGATCGGATTTACTGAAAATACCATTAA1500               AAAATATCTACAATGCACTAACATCCAGACAGTGACGGTGCCTGTTCCTGCGAAGTTTTT1560               ACGTGCTTCAAATGTACCGACTGGATTGCTTAATGAAATGATTGCTTATCTCAACTCGGA1620               AGAACGCAATCATCATAATTTTTCAGAACTTTTGCTTTTTTCTTGCCTGTCTATTTTTGC1680               CGCATGCAAAGGTTTCATTACACTATTAACTAACGGTGTGCTATCCGTTTCTGGGAAAGT1740               GAGAAATATTGTCAACATGAAGCCGGCGCACCCATGGAAGCTGAAAGATATTTGTGACTG1800               CCTGTACATCAGTGAAAGCCTGTTGAAGAAAAACTTAAGCAAGAGCAAACGACATTCTCA1860               CAGATTCTTTTAGATGCAAGAATGCAGCACGCAAAAAATTTGATACGCGTAGAAGGTTCA1920               GTCAATAAAATTGCCGAACAATGTGGTTATGCCAGTACATCTTATTTTATTTATGCGTTC1980               CGCAAACATTTCGGCAACAGTCCGAAGAGAGTTTCTAAGGAGTACCGTTGTCAAAGTCAC2040               ACGGGTATGAATACGGGCAACACGATGAATGCTTTAGCTATTTGATTATTTGCTAACGAG2100               TAGTCAACCACACACGCTGCGTAAGAATTAAATGGGGCAGCCATTCCCTGCCCCGCGTTG2160               TTTTTAGGCGATATATTTATTGAAATAAATAAGTGACATCCATCACATATTTATGCACTT2220               GCATAACCTGTTGCATGATTATTTATGATCTCAATTCTGCATTTTGTCAGTAAAATGCAA2280               TAATTTATTAAATATCAATAAATTAGTTGTTTATCGGCGAGAAATTACTTAATAGAACAG2340               AAAGTAATGTCAACGCTTTATGGACTGTTTTTTCCCTTTTTTTAGCTAAATCTGCTATCT2400               CTTTATGTGACTAACTTCACTTACATCCACTTATTTCTCTTCGTAAAATTACTTTGGAAT2460               TAAGTACAATAAGAAGAGGAACATTTATGAAGTCTGCATTAAAGAAAAGTGTCGTAAGTA2520               CCTCGATATCTTTGATACTGGCATCTGGTATGGCTGCATTTGCTGCTCATGCGGCAGATG2580               ATGTAAAGCTGAAAGCAACCAAAACAAACGTTGCTTTCTCAGACTTTACGCCGACAGAAT2640               ACAGTACCAAAGGAAAGCCAAATATTATCGTACTGACCATGGATGATCTTGGTTATGGAC2700               AACTTCCTTTTGATAAGGGATCTTTTGACCCAAAAACAATGGAAAATCGTGAAGTTGTCG2760               ATACCTACAAAATAGGGATAGATAAAGCCATTGAAGCTGCACAAAAATCAACGCCGACGC2820               TCCTTTCATTAATGGATGAAGGCGTACGTTTTACTAACGGCTATGTGGCACACGGTGTTT2880               CCGGCCCCTCCCGCGCCGCAATAATGACCGGTCGAGCTCCCGCCCGCTTTGGTGTCTATT2940               CCAATACCGATGCTCAGGATGGTATTCCGCTAACAGAAACTTTCTTGCCTGAATTATTCC3000               AGAATCATGGTTATTACACTGCAGCAGTAGGTAAATGGCACTTGTCAAAAATCAGTAATG3060               TGCCGGTACCGGAAGATAAACAAACGCGTGACTATCATGACACCTTCACCACATTTTCTG3120               CGGAAGAATGGCAACCTCAAAACCGTGGCTTTGATTACTTTATGGGATTCCACGCTGCAG3180               GAACGGCATATTACAACTCCCCTTCACTGTTCAAAAATCGTGAACGTGTCCCCGCAAAAG3240               GTTATATCAGCGATCAGTTAACCGATGAGGCAATTGGCGTTGTTGATCGTGCCAAAACAC3300               TTGACCAGCCTTTTATGCTTTACCTGGCTTATAATGCTCCGCACCTGCCAAATGATAATC3360               CTGCACCGGATCAATATCAGAAGCAATTTAATACCGGTAGTCAAACAGCAGATAACTACT3420               ACGCTTCCGTTTATTCTGTTGATCAGGGTGTAAAACGCATTCTCGAACAACTGAAGAAAA3480               ACGGACAGTATGACAATACAATTATTCTCTTTACCTCCGATAATGGTGCGGTTATCGATG3540               GTCCTCTGCCGCTGAACGGGGCGCAAAAAGGCTATAAGAGTCAGACCTATCCTGGCGGTA3600               CTCACACCCCAATGTTTATGTGGTGGAGAAGGAAAACTTCAACCCGGTAATTATGACAAG3660               CTGATTTCCGCAATGGATTTCTACCCGACAGCTCTTGATGCAGCCGATATCAGCATTCCA3720               AAAGACCTTAAGCTGGATGGCGTTTCCTTGCTGCCCTGGTTGCAAGATAAGAAACAAGGC3780               GAGCCACATAAAAATCTGACCTGGATAACCTCTTATTCTCACTGGTTTGACGAGGAAAAT3840               ATTCCATTCTGGGATAATTACCACAAATTTGTTCGCCATACAGTCAGACGATTACCCGCA3900               TAACCCCAACACTGAGGACTTAAGCCAATTCTCTTATACGGTGAGAAATAACGATTATTC3960               GCTTGTCTATACAGTAGAAAACAATCAGTTAGGTCTCTACAAACTGACGGATCTACAGCA4020               AAAAGATAACCTTGCCGCCGCCAATCCGCAGGTCGTTATAGAGATGCAAGGCGTGGTAAG4080               AGAGTTTATCGACAGCAGCCAGCCACCGCTTAGCGAGGTAAATCAGGAGAAGTTTAACAA4140               TATCAAGAAAGCACTAAGCGAAGCGAAATAACTAAACCTTCATGCGGCGGATTTTTCCGC4200               CGCCTTATTGAGCGAGATAGCGATGCACGTTACAGCCAAGCCCTCCAGTTTTCAATGTAA4260               TCTCAAATGTGATTACTGTTTTTACCTTGAAAAAGAGTCGCAGTTTACTCATGAAAAATG4320               GATGGATGACAGCACTTTGAAAGAGTTCATCAAACAATATATCGCAGCGTCTGGCAATCA4380               GGTCTATTTTACCTGGCAAGGCGGTGAACCCACTCTGGCTGGCCTGGATTTTTTCCGTAA4440               AGTTATTCACTATCAACAACGCTATGCAGGCCAAAAACGTATTTTTAATGCATTACAAAC4500               GAATGGCATTTTATTGAATAATGAATGGTGTGCCTTCTCAAAGAACATGAATTTCTGGTG4560               GTATCTCGATCGATGGCCCCCAGGAGTTACATGACCGTTACAGACGCAGTAATTCAGGTA4620               ACGGTACTTTTGCAAAAGTGATAGCAGCCATCGAGCGTCTGAAATCATATCAAGTAGAGT4680               TTAATACGTTAACCGTCATTAATAACGTTAATGTCCATTACCCTCTTGAGGTTTATCATT4740               TTTTAAAATCTATCGGCAGTAAACATATGCAATTTATCGAATTGCTAGAAACCGGGACGC4800               CGAATATTGATTTCAGTGGTCATAGTGAGAACACATTCCGTATCATTGATTTTTCTGTGC4860               CTCCCACGGCTTATGGCAAGTTTATGTCAACCATTTTTATGCAATGGGTTAAAAACGATG4920               TGGGTGAAATTTTCATCCGTCAGTTTGAAAGCTT4954                                         (2) INFORMATION FOR SEQ ID NO:19:                                              (i) SEQUENCE CHARACTERISTICS:                                                  (A) LENGTH: 3796 base pairs                                                    (B) TYPE: nucleic acid                                                         (C) STRANDEDNESS: double                                                       (D) TOPOLOGY: linear                                                           (ii) MOLECULE TYPE: Genomic DNA                                                (vi) ORIGINAL SOURCE:                                                          (A) ORGANISM: Escherichia coli                                                 (B) STRAIN: Clinical Isolate EC- 39                                            (xi) SEQUENCE DESCRIPTION: SEQ ID NO:19:                                       AAGCTTAATCGCGTGAATCAGGAGTAAAAAAATGACAACCCAGACTGTCTCTGGTCGCCG60                 TTATTTCACGAAAGCGTGGCTGATGGAGCAGAAATCGCTTATCGCTCTGCTGGTGCTGAT120                CGCGATTGTCTCGACGTTAAGCCCGAACTTTTTCACCATCAATAACTTATTCAATATTCT180                CCAGCAAACCTCAGTGAACGCCATTATGGCGGTCGGGATGACGCTGGTGATCCTGACGTC240                GGGCATCGACTTATCGGTAGGTTCTCTGTTGGCGCTGACCGGCGCAGTTGCTGCATCTAT300                CGTCGGCATTGAAGTCAATGCGCTGGTGGCTGTCGCTGCTGCTCTCGCGTTAGGTGCGCA360                ATTGGTGCGGTAACCGGGGTGATTGTAGCGAAAGGTCGCGTCCAGGCGTTTATCGCTACG420                CTGGTTATGATGCTTTTACTGCGCGGCGTGACCATGGTTTATACCAACGGTAGCCCAGTG480                AATACCGGCTTTACTGAGAACGCCGATCTGTTTGGCTGGTTTGGTATTGGTCGTCCGCTG540                GGCGTACCGACGCCAGTCTGGATCATGGGGATTGTCTTCCTCGCGGCCTGGTACATGCTG600                CATCACACGCGTCTGGGGCGTTACATCTACGCGCTGGGCGACAACGAAGCGACAACGCGT660                CTTTCTGGTATCAACGTCAATAAAATCAAAATCATCGTCTATTCTCTTTGTGGTCTGCTG720                GCATCGCTGGCGGGATCATAGAAGTGGCGCGTCTCTCCTCCGCACAACCACGGCGGGGAC780                TGGCTATGAGCTGGATGCTATTGCTGCGGTGGTTCTGGGCGGTACGAGTCTGGCGGGCGG840                AAAAGGTCGCATTGTTGGGACGTTGATCGGCGCATTAATTCTTGGCTTCCTTAATAATGG900                ATTGAATTTGTTAGGTGTTTCCTCCTATTACCAGATGATCGTCAAAGCGGTGGTGATTTT960                GCTGGCGGTGCTGGTAGACAACAAAAAGCAGTAATAACGACTACAGGCACATCTTGAATA1020               TGAACATGAAAAAACTGGCTACCCTGGTTTCCGCTGTTGCGCTAAGCGCCACCGTCAGTG1080               CGAATGCGATGGCAAAAGACACCATCGCGCTGGTGGTCTCCACGCTTAACAACCCGTTCT1140               TTGTATCGCTGAAAGATGGCGCGCAGAAAGAGGCGGATAAACTTGGCTATAACCTGGTGC1200               TGGACTCCCAGAACAACCCGGCGAAAGAGCTGGCGAACGTGCAGGACTTAACCGTTCGCG1260               GCACAAAAATTCTGCTGATTAACCCGACCGACTCCGACGCAGTGGGTAATGCTGTGAAGA1320               TGGCTAACCAGGCGAACATCCCGGTTATCACTCTTGACCGCCAGGCAACGAAAGGTGAAG1380               TGGTGAGCCACATTGCTTCTGATAACGTACTGGGCGGCAAAATCGCTGGTGATTACATCG1440               CGAAGAAAGCGGGTGAAGGTGCCAAAGTTATCGAGCTGCAAGGCATTGCTGGTACATCCG1500               CAGCCCGTGAACGTGGCGAAGGCTTCCAGCAGGCCGTTGCTGCTCACAAGTTTAATGTTC1560               TTGCCAGCCAGCCAGCAGATTTTGATCGCATTAAAGGTTTGAACGTAATGCAGAACCTGT1620               TGACCGCTCATCCGGATGTTCAGGCTGTATTCGCGCAGAATGATGAAATGGCGCTGGGCG1680               CGCTGCGCGCACTGCAAACTGCCGGTAAATCGGATGTGATGGTCGTCGGATTTGACGGTA1740               CACCGGATGGCGAAAAAGCGGTGAATGATGGCAAACTAGCAGCGACTATCGCTCAGCTAC1800               CCGATCAGATTGGCGCGAAAGGCGTCGAAACCGCAGATAAAGTGCTGAAAGGCGAGAAAG1860               TTCAGGCTAAGTATCCGGTTGATCTGAAACTGGTTGTTAAGCAGTAGTTTTAATCAGGTT1920               GTATGACCTGATGGTGACATAAATACGTCATCGACAGATGAACGTGTAATATAAAGAAAA1980               GCAGGGCACGCGCCACCCTAACACGGTGGCGCATTTTATGGACATCCCGAATATGCAAAA2040               CGCAGGCAGCCTCGTTGTTCTTGGCAGCATTAATGCTGACCACATTCTTAATCTTCAATC2100               TTTTCCTACTCCAGGCGAAACGTAACCGGTAACCACTATCAGGTTGCATTTGGCGGCAAA2160               GGCGCGAATCAGGCTGTGGCTGCTGGGCGTAGCGGTGCGAATATCGCGTTTATTGCCTGT2220               ACGGGTGATGACAGCATTGGTGAGAGCGTTCGCCAGCAGCTCGCCACTGATAACATTGAT2280               ATTACTCCGGTCAGCGTGATCAAAGGCGAATCAACAGGTGTGGCGCTGATTTTTGTTAAT2340               GGCGAAGGTGAGAATGTCATCGGTATTCATGCCGGCGCTAATGCTGCCCTTTCCCCGGCG2400               CTGGTGGAAGCGCAACGTGAGCGTATTGCCAACGCGTCAGCATTATTAATGCAGCTGGAA2460               TCACCACTCGAAAGTGTGATGGCAGCGGCGAAAATCGCCCATCAAAATAAAAACTATCGT2520               TCGCTTAACCCGCTCCGGCTCGCGAACTTCCTGACGAACTCTGCGCTGTGGACATTATTA2580               CGCCAAACGAAACGGAAGCAGAAAAGCTCACCGGTATTCGTGTTGAAAATGATGAAGATG2640               CAGCGAAGGCGGCGCAGGTACTTCATGAAAAAGGTATCCGTACTGTACTGATTACTTTAG2700               GAAGTCGTGGTGTATGGGCTAGCGTGAATGGTGAAGGTCAGCGCGTTCCTGGATTCCGGG2760               TGCAGGCTGTCGATACCATTGCTGCCGGAGATACCTTTAACGGTGCGTTAATCACGGCAT2820               TGCTGGAAGAAAAACCATTGCCAGAGGCGATTCGTTTTGCCCATGCTGCCGCTGCGATTG2880               CCGTAACACGTAAAGGCGCACAACCTTCCGTACCGTGGCGTGAAGAGATCGACGCATTTT2940               TAGACAGGCAGAGGTGACGCTTGGCTACAATGAAAGATGTTGCCCGCCTGGCGGGCGTTT3000               CTACCTCAACAGTTTCTCACGTTATCAATAAAGATCGCTTCGTCAGTGAAGCGATTACCG3060               CAAAGTGAGCGCGATTAAAGACTCAATTACGCGCCATCAGCTCTGGCGCGTAGCCTCAAA3120               CTCAATCAAACACATACCATTGGCATGTTGATCACTGCCAGTACCAATCCTTTCTATTCA3180               GAACTGGTGCGTGTCGTTGAACGCAGCTGCTTCGAACGCGGTTATAGTCTCGTCCTTTGC3240               AATACCGAAGGCGATGAACAGCGGATGAATCGCAATCTGGAAACGCTGATGCAAAAACGC3300               GTTGATGGCTTGCTGTTACTGTGCACCGAAACGCATCAACCTTCGCGTGAAATCATGCAA3360               CGTTATCCGACAGTGCCTACTGTGATGATGGACTGGGCTCCGTTCGATGGCGACAGCGAT3420               CTTATTCAGGATAACTCGTTGCTGGGCGGAGACTTAGCAACGCAATATCTGATCGATAAA3480               GGTCATACCCGTATCGCCTGTATTACCGGCCCGCTGGATAAAACTCCGGCGCGCTGCGGT3540               TGGAAGGTTATCGGGCGGCGATGAAACGTGCGGGTCTCAACATTCCTGATGGCTATGAAG3600               TCACTGGTGATTTTGAATTTAACGGCGGGTTTGACGCTATGCGCCAACTGCTATCACATC3660               CGCTGCGTCCTCAGGCCGTCTTTACCGGAAATGACGCTATGGCTGTTGGCGTTTACCAGG3720               CGTTATATCAGGCAGAGTTACAGGTTCCGCAGGATATCGCGGTGATTGGCTATGACGATA3780               TCGAACTGGCAAGCTT3796                                                           (2) INFORMATION FOR SEQ ID NO:20:                                              (i) SEQUENCE CHARACTERISTICS:                                                  (A) LENGTH: 5541 base pairs                                                    (B) TYPE: nucleic acid                                                         (C) STRANDEDNESS: double                                                       (D) TOPOLOGY: linear                                                           (ii) MOLECULE TYPE: Genomic DNA                                                (vi) ORIGINAL SOURCE:                                                          (A) ORGANISM: Escherichia coli                                                 (B) STRAIN: Clinical Isolate EC- 625                                           (xi) SEQUENCE DESCRIPTION: SEQ ID NO:20:                                       AAGCTTAAGCCTGCATTTGCTCAATGAAGCGCAGAATGAGCTGGAACTGTCAGAAGGCAG60                 CGACGATAACGAAGGTATTAAAGAACGTACCAGCTTCCGTCTGGAGCGTCGGGTCGCCGG120                AGTGGGTCGTCAAATGGGCCGCGGTAACGGCTATCTGGCAACCATCGGCGCGATTTCTCC180                GTTCGTTGGTCTGTTTGGTACGGTCTGGGGCATCATGAACAGCTTTATTGGTATCGCGCA240                AACGCAGACCACTAACCTGGCAGTCGTTGCGCCGGGTATCGCAGAAGCTCTGTTAGCAAC300                GGCAATCGGCCTCGTGGCAGCGATTCCTGCGGTCGTTATCTATAACGTATTTGCACGCCA360                GATTGGCGGCTTTAAAGCGATGCTGGGTGATGTTGCAGCGCAGGTATTGTTGCTGCAAAG420                CCGTGACCTGGATCTGGAAGCCAGCGCCGCTGCGCATCCGGTTCGTGTCGCACAAAAATT480                ACGCGCAGGATAATATCCGATGGCAATGCATCTTAACGAAAACCTCGACGATAACGGCGA540                AATGCATGATATCAACGTGACGGCGTTTATCGACGTGATGTTGGTTCTGCTGATTATCTT600                TATGGTGGCGGCACCGTTAGCGACGGTAGATGTGAAGGTGAACTTGCCTGCTTCTACCAG660                CACGCCGCAGCCGCGGCCGGAAAAACCGGTTTATCTGTCGGTGAAGGCAGACAACTCGAT720                GTTTATCGGTAACGATCCGGTCACCGATGAAACAATGATTACGGCGTTGAATGCGTTAAC780                CGAAGGCAAGAAAGACACCACCATCTTCTTCCGAGCGGATAAAACCGTCGATTACGAGAC840                GTTGATGAAGGTAATGGATACGCTGCATCAGGCGGGTTACCTGAAGATAGGTCTGGTCGG900                CGAAGAAACCGCCAAAGCGAAGTAAAGTAGAATTGCCTGATGCGCTACGCTCATCAGGCC960                TACAAAATCTATTGCAACATGTTGAATCTTCGTGCGTTTGTAGGCCGGATAAGGCGTTCA1020               CGCGCATCCGGCATTAGGTGCTCAATGCCTGATGCGCTACGTTTATCAGGCCTACAAAAT1080               CTATTGCAACATGTTGAATCTTCATGCGTTTGTAGGCGGATAAGGCGTTTTCGCACATCA1140               GGTAAGAGTGAATTCACAATGATGCCCGGTTGCTTTTCACAACCGGGCATTTTTTTAACC1200               TAAATGCTCGCCGCCGCACACACCGTGCACTTCTGCGGTGACGTAGCTCGACTCCTGACT1260               TGCCAGATAAACATATACTGGGGCCAGTTCCGCCGGTTGCCCCGCACGCTTCATCGGCGT1320               TTTCTGACCAAACTGCGGGATCTTATCCTGCGTTTGTCCGCCGGAAATTTGCAGTGCCGT1380               CCAGATAGGGCCTGGCGCGACAATATTCACCCGAATACCTTTCTCCGCGACCTGTTTTGC1440               CAGGCCACGGCTGTAGTTCAGAATCGCCGCCTTCGTAGCCGCATAGTCCAGTAAATGCGG1500               ACTTGGCTGGTATGCCTGGATTGACGAAGTGGTGATAATACTTGCACCTTTCGGTAGCAG1560               GGGGATCGCTTCCTGGGTTAGCCAGAACAGCGCGAAAACGTTAATGGCAAAGGTCTTTTG1620               AAACTGTTCGCTGGTGAGGTCTGCAATATCAGGAATGGCAACCTGTTTCCCGGCGACCAG1680               CGCCATAATATCCAGCCCGCCTAACGCCTTGTGCGCTTCGTGAACCAGCGAACGGGCGAA1740               TTTCTCATCGCTTAAATCGCCTGGCAGCAGAACGGCTTTGCGTCCGCATTCTTCAATGAT1800               CTTTTTCACATCCTGAGCGTCTTCTTCTTCCACGGGAAGATAACTGATCGCCACGTCAGC1860               CCCTTCACACGCGTAAGATGGCGGCAGCGCGACCGATTCCGGAATCGCCCCCTGTCACCA1920               GTGCTTTACGATCTTTCAGGCGACCGCTACCAACATAGGTTTTCTCGCCGCAATCCGGTA1980               CCGGTGTCATCTTCGCCTGGATGCCTGGCGTCGGTTGTTTCTGTTTGGGATATTCACCAG2040               TGTAATACTGCGTGGTCGGGTCTTTTAAATGAGACATCGTTTTTCTCCCTTCAGGTTCAA2100               CGTCCTTTAAGGGTAGACGCTCTCGATGCGTTGATAAGGGAACCAGGAAGATCCCTAACC2160               CTCAGAATTATGCGACAAAGGTTTAACGGATATGTTGATTTGCTGTTGCGCGCTGTTTAC2220               TCAATTGCGATATACTGTTGCCCGTTTTAACTACACGACAGGAATGTATGGAACGTTTTC2280               TTGAAAATGCAATGTATGCTTCTCGCTGGCTGCTTGCCCCCGTGTACTTTGGCCTTTCGC2340               TGGCGTTAGTTGCCCTGGCGCTGAAGTTCTTCCAGGAGATTATTCACGTACTGCCGAATA2400               TCTTCTCGATGGCGGAATCAGATTTGATCCTCGTGTTGCTGTCGCTGGTGGATATGACAC2460               TGGTTGGCGGTTTACTGGTGATGGTGATGTTTTCCGGTTATGAGAATTTCGTCTCGCAGC2520               TGGATATCTCCGAGAACAAAGAGAAGCTGAACTGGCTGGGGAAAATGGACGCAACGTCGC2580               TGAAAAACAAAGTAGCAGCGTCGATTGTGGCAATTTCTTCCATTCACTTACTGCGCGTCT2640               TTATGGATGCGAAAAATGTCCCTGATAACAAACTGATGTGGTACGTCATTATCCATCTGA2700               CGTTTGTGCTCTCTGCATTTGTGATGGGCTATCTTGACCGACTGACTCGTCATAATCACT2760               GATCTTATGCGGGCGCGGTTCTCGCGCCCGTTATTAACAGGTCATTTATCGGAAGACGCC2820               TGCCACAGATTCAGCTCGCCATCGGCGATATGCTGATCAATCTGCGCCAGCTCCTCGGTG2880               CTAAATGTCAGATTATTCAGCGCCTGCACGTTCTCCTCAAGTTGTCCGCGCGGCTGGCAC2940               CAATCAATACCGACGTCACGCGATCATCTTTCAGCAACCAGCTTAACGCCATTTGCGCCA3000               TTGATTGTCCACGCTGCTGTGCCATTTCATTCAATAAGTGTAGGCTGTTGAGGTTGGCTT3060               CGGTAAGCATTTTCGGCGTCAGACCACGAACTTTATTCCCTTCACGATGCATCCGTGAAT3120               CTTGCGGAATGCCGTTGAGATATTTTCCGGTCAGCAATCCCTGAGCCAGAGGAGTAAAGG3180               CAATACAGCCCACGCCGTTATTTTGCAGGGTATCCAGCAGGCCGCTTTTATCCACCCAGC3240               GGTTCAGTAAATTGTACGAAGGTTGATGAATTAACAGCGGAATTTTCCACTCGCGCAGCA3300               ACTCAACCATTTTTTGCGTCCGCTCTGGCGAGTAAGAGGAGATCCCGACATAAAGCGCCT3360               TACCGCTTTGTACCGCATGAGCCAGCGCAGAGGCGGTTTCTTCCATCGGCGTATTTTCAT3420               CGACGCGATGAGAGTAAAAGATATCGACATACTCAAGCCCCATACGCTTCAGGCTTTGGT3480               CGAGGCTGGAGAGCAGGTATTTACGTGAACCGCCAGAGCCGTAAGGGCCGGGCCACATAT3540               CGTAGCCAGCCTTGGTAGAGATAATCAGTTCATCGCGATAAGCGGCAAAATCCTCCCGCA3600               GCAGGCGACCAAAGTTCTCTTCTGCGCTTCCTGGAGGCGGCCCGTAATTGTTGGCTAAAT3660               CAAAGTGCGTAATGCCTAAATCAAACGCTTTACGCAGGATTGCACGCTGTGATTCCAGCG3720               CGTTAACGTGACCGAAATTGTGCCATAAACCGAGCGATAACGCGGGCAGGCGTAAACCAC3780               TTTTTCCGCAATAGCGGTACTGCATCTGCCCGTAACGTTCGGGTTCGCTAACCAGACCAT3840               GACCTCTCCTTTCCACCGTTCAATTTCGAAACAATGTTTCTAGTTTAGCGATTCGCCAGC3900               GCGTATCCCGTAGTCTGGCTCACAGAGTGACGAAAAATTGGCAAAAACACGCGCTTATGC3960               TTTGCTTAAAAAAACACCAGTTGAGGAGTGCAACGATGCCGCGTTTAACCGCCAAAGATT4020               TCCCACAAGAGTTGTTGGATTACTACGACTATTACGCTCACGGGAAAATCTCGAAACGTG4080               AGTTCCTCAATCTTGCGGCGAAGTATGCGGTGGGCGGGATGACGGCATTAGCGTTGTTTG4140               ATTTGCTCAAGCCAAATTATGCGCTGGCGACTCAGGTAGAGTTTACCGACCTGGAGATTG4200               TTGCTGAGTACATCACGTATCCTTCGCCAAATGGTCACGGCGAGGTACGGGGTTATCTGG4260               TGAAACCCGCAAAAATGAGCGGCAAAACGCCAACCGTGGTGGTGGTGCATGAGAATCGTG4320               GACTGAATCCGTATATCGAAGATGTGGCACGGCGAGTGGCGAAGGCGGGGTATATCGCCC4380               TGGCACCTGACGGCTTAAGTTCCGTTGGAGGTTATCCGGGAAATGATGATAAAGGTCGTG4440               AGCTGCAACAGACAGGTTGATCCAACCAAACTGATGAATGATTTCTTTGCCGCAATTGAG4500               TTTATGCAACGCTATCCGCAAGCGACAGGCAAAGTGGGTATTACCGGATTTTGCTATGGC4560               GGTGGCGTATCGAACGCGGCGGCTGTCGCGTATCCGGAACTGGCCTGCGCGGTGCCGTTT4620               TATGGTCGTCAGGCACCCACTGCCGATGTGGCGAAGATTGAAGCGCCTTTACTACTCCAC4680               TTCGCGGAACTGGACACCCGAATCAACGAGGGCTGGCCTGCTTACGAGGCGGCGTTGAAA4740               GCCAATAATAAGGTTTATGAGGCGTATATCTATCCGGGGGTTAATCACGGATTCCATAAT4800               GATTCCACGCCCCGTTATGACAAATCTGCCGCCGATCTTTCCTGGCAAAGGACACTGAAA4860               TGGTTCGATAAATATCTCTCCTGATAGGTTTATCTCTTACGGGATTACGTCTTAAACAAG4920               CATGAAAAAATAGCGTGCGCAAAAGTCGTTCTTTGCCTAAAATATCGCTATATATAACAA4980               TATATAGCGAATGAGGTGAACGATGAATAACCATTTTGGTAAAGGCTTAATGGCGGGATT5040               AAAAGCAACGCATGCCGACAGTGCGGTTAATGTGACAAAATACTGTGCCGATTATAAACG5100               CGGTTTTGTATTAGGCTACTCACACCGGATGTACGAAAAGACCGGAGATCGCCAGCTTAG5160               CGCCTGGGAAGCGGGTATTCTGACGCGCCGCTATGGACTGGATAAAGAGATGGTAATGGA5220               TTTCTTTCGTGAGAATAATTCCTGTTCTACGTTGCGCTTTTTTATGGCCGGTTATCGCCT5280               CGAAAATTGATCAAACATACGTATTATCTTGCTTTAATTAATTACACTAATGCTTCTTCC5340               CTTCGTTTTAGCGCCCCGCCGCAGTATCATGATATCGATAACCATAATAAATGTGTGGTA5400               AATGGCGCATCGATCGCATTATTGATTTTGCGATTGAGGCAAAATATATGCCAGGTCTTC5460               GCAACGGAATAACTATAAATGACTGGAGATAACACCCTCATCCATTCTCACGGCATTAAC5520               CGTCGTGATTTCATGAAGCTT5541                                                      (2) INFORMATION FOR SEQ ID NO:21:                                              (i) SEQUENCE CHARACTERISTICS:                                                  (A) LENGTH: 6317 base pairs                                                    (B) TYPE: nucleic acid                                                         (C) STRANDEDNESS: double                                                       (D) TOPOLOGY: linear                                                           (ii) MOLECULE TYPE: Genomic DNA                                                (vi) ORIGINAL SOURCE:                                                          (A) ORGANISM: Enterobacter cloacae                                             (B) STRAIN: Clinical Isolate ET- 12                                            (xi) SEQUENCE DESCRIPTION: SEQ ID NO:21:                                       AAGCTTGCCCGCATCATTCAGGAGCAGGGGCGTCGCGACCAGTTAGGTGTGAAGTTTGGC60                 AGCGGTGACAGCCCGGACTGCCGGGGGATCACGGTTCCGGAACTGCAGAGTATCGACTTC120                GACAAAATCAACTTCTCTGACTTCTACGAGGATTTGATGAAGAACCAGAAAATCCCCGAT180                ACCAGCGCGCAGGTCAAGCAGATTAAGGATCGCATCGCCGCGCAGGTGAACCAGCAGGGA240                GGTGGCAAATGAAGCGTGTCCTCTGTGGCCTGCTTATGGCGCTGGCGAGCCATACGGCAC300                TGGCCGATGAGATTGTGACGCCGGCTGAGCCGTTCACCGGCTGGTCCTGGTACAACGAAC360                CGAAAAAGCCCCCTGAGCAGCCCCGGAAACCGCAGCAGCCAGCACCGCAGCCATTCCGGA420                TCTCAGCAAAATGTCCCCGATGGAGCAGGCCAGGGTGCTGAAAGGGTATACACAGGAGGC480                GCTTAACCGCGCCATCCTGTACCCCTCAAGGGAAAACACGGCGACGTTCCTGCGCTGGCA540                GAAGTTCTGGACGGACCGGGCATCGATGTTCAGCCAGTCCTTTGCGGCGGCGCAGCTGAG600                CCATCCGGACCTCGACTACAACCTGGAGTATCCGCACTACAACAGCATGGCGCCGTTTAT660                GCAGACCCGTGACCAGCAGACGCGGCAGAGCGCCGTGGAGCAGCTTGCGCAGAGTACGGT720                CTGTTCTACTTCTACCGGGGCAGTGACCCGATTGATGTGCAGATGGCGGGCGTGGTGGCT780                GACTTTGCGAAAACCAACGGGATCTCACTCATTCCGGTCTCGGTTGACGGACAGGTGGCG840                GCCACCCTGCCGCAAAGCCGTCCGGACACCGGACAGTCCCGGTCGATGAATATCACGCAC900                TTTCCGGCGCTCTTCCTGGTTGACCCGCGCAACCAGAACTACCGTGCCCTGTCCTATGGC960                TTCATGACCCAGGATGACCTGTCAAAACGATTCCTGAACGTGGCCACCGGCTTTAAACCC1020               AATTCCTGAGAGCCTTTTATGACAAAAACACTGTTTACCTCATCCGCGATGCAGGGCGGG1080               CTGCCCTGTATTCCTTCGTCCTCGGCCCGGCACTGGTGCTGTATGTGTTTGTGATGCTGG1140               CGGCATCAGACGGCTCACTTTCCCGGCAATTCCTGACGACCTTTCATCACCTGACTGAGG1200               GTGCGCCTGCCGGCAAGGTGATGGGATGTGTTAATGAACATGAGATGGCAGGGCGTTTCT1260               CGCCACCTGAACCCGGAGAGTCGTTAAAGCCCGTGCCTTCCGTTTTAGATAAAGCACCGC1320               CTGAAGTGTTATGTCAGCTCGGGCCCGTTGACAGCGATTCGTGGGCGCGTACGACAGATG1380               CAACGTTGCTCAACACCTGGATTATCTCGGTGATGTTTGGCTTTGGTGTGTGGTTTGTTT1440               TATATGGCCTGTCCCGGGCCGCTCAGCGTCGCATTTCACCAGACACACATTCTGTACTGG1500               TACGGCAGAACAAGGAGACACAGGAATGAAACCAACTCTTCTCGCAGGACTGATTTTCTG1560               GGGCATGATGGCGCGCCGTACTGAGCGAGCTGATGACCTGGTCCGTGGAGCATACACAGC1620               AGGGCCTGCTGTGGCTGTGCAATGGGATGTGGGCCGGGGCGGCTGGCATGGTGATTTATG1680               CAGGTTATCGCTGGTACCGTGACGAAAGAGGGCAAACGCATAAGGAAGGCGATCATGAAC1740               ATTAAAACCGGACTCACGGCTCTGCTGATGTGCCTGCCCCTGCTGGCGAACGCGGGGGCG1800               CGCGAGGAGTTAATGGCGCTTGAAGCGACAAAAACAACCTCTGCTGACGCTGCAGCCATC1860               ACCGCCTCCACCATTCCGGTACCTGCGCCGGCCAGCCTGATGGCGCTGCCGGACGGACGT1920               CGGGCTAACATGAAAGATTATGCCGTGGTGCTTTTTATGCAGGCACACTGCCAGTACAGC1980               GCGAAGTTTGACCCGCTGCTGAAGGGCTGGGCTGATGAGCATTCTGTCAGGGTTTATCCA2040               TACACCCTGGACGGCGGCGGTGATGTGTCTTACCGACGCCGATGATCCCGCGCAAGACGG2100               ACCCGAATTCTCCCATTGCAGACGAGATTGTCACCTTCTTCGGAAACGGGCTGCCGATTG2160               CGACACCAACGGCCTTTATGGTCAACGTTAACACCCTGAAAGCCTACCCGCTGACCCAGG2220               GTGTGATGGACATCCCCGCTCTTGAGAGCCGTATGGCCAGCCTGATTCAGGCTGACATGG2280               ACAACGTCGATCCGAAAACGCTGCCGCCCATGCCGGCAAGTGCGCAGGTCACCCCTCAGT2340               AATACAAACGGACTACAAAATGACGACAAATACGTATGCGTTATCGCGTACCGAGCGCGT2400               GTGGCTGTTATTCAGCGTGACGCTGCTTGTGTCCGCAGCTTTCTATGGGGTACTGGCCCA2460               CCGGGTGGTCAGCGTCTGACCGTCAGACTGACAACTGTTTGCAGGACTTTCCGGTGCTCC2520               TGCTTATCTCGCTGAGTATCGGATTCTTTTTCACCGTCACCGGGCTGTACGTCTGCCGGC2580               AGACCCTGGTCAGGAAACCCCGGGAGGAGATTGCATGAGGCACATCAGACTGAAGACGTT2640               TATCCGAAACCAGGCTATCGGGATACTGAAAGACAGTAGTGAGGATACGGAAACCCGAAA2700               ATGGACGGATTTGTTAACCCTGAAACTGTTTTTATGCCTTAATTTTTACCGCCGTAGTCG2760               AAAGGGTATACGTGAAGTGCGCCATCACAACGCTCAGTGCGATCTCCGTTGACCGCTCCG2820               AACAGTTTACGCTCTCGCTTCTCATCCACTATCCACAGTACCTGTTGTGGGGCGTTATGG2880               CCGCGATTATCGCGCTCATTGCGGTGAATTTACTCGTCTGCGGCTGGTTCTGTCTGGCCA2940               CATATCTTTGCCGCAAACTGAACCGGACTGACATCCCGGCAGGCAAGGATATGCAAGCTG3000               TGGAGGTGCCTAATGATTAAGGCGCTTATTACGGCAGGGGTTGTGTTCTTCTCAGGTCTG3060               GCAGCGCTGCCTGCTCAGGCGGACGTCAATGGTGACTCAACGGCTTCTTTGGCAAGCTGG3120               GCTACAGCGGCAACGTCTCTCAGGCGCAGGCCTGGCAGGGGCAGGCGGCCGGGTATTTCT3180               CCGGCGGGTCGGTCTACCTGCGAAACCCCGTCAAAAACGTTCAGCTGATCTCGATGCAGC3240               TGCCGTCCCTGAACGCCGGCTGCGGCGGTATCGATGCCTACCTGGGGTCATTCAGCATGA3300               TCAGCGGTGAGGAAATTCAGCGATTCGTGAAGCAAATCATGAGTAACGCGGCTGGCTATG3360               CATTCGACCTGGCACTGCAGACGATGGTCCCGGAGCTGAAGCAGGCGAAAGATTTCCTGC3420               AGAAGCTGGCCAGTGATGTTAACTCCATGAACATGAGTTCGTGCCAGGCCGCTCAGGGCA3480               TCATAGGCGGGTTGTGGCCCGTAACGCAGGTGTCACAGCAGAAAATCTGCCAGGACATTG3540               CCGGCGAAACCAACATGTTTGCTGACTGGGCGGCCTCCCGCCAGGGCTGCACCGTCGGAG3600               GACAGGGGGATAAAGTCACGGCCAAAGCCGGCGACGCAGAAAAAAGACCCAGGTACTGAA3660               AAACAAAAACCTTATCTGGGACACGCTCAGTAAGAACGGGCTGCTTGGTAACGATCGCGC3720               CCTGAAGGAGCTGGTCATGAGTACTGTCGGCTCCATCATTTTCAACAAAACCGGAGACGT3780               GACATCCTGACGCCGCTGGTCGATACCGCGACCTGATTAAAGTTCTGATGCGCGGGGGAA3840               CAGCGAAGGTCTACGGGTGCGATGAGGCAACACTCTGTCTGGGGCCTGTCGTTACTAACC3900               TGACGATTACTGAGTCCAACGCTCTGGTCACACTGGTCAAAAAACTGATGCTCTCGATGC3960               AGAACAAACTTGTCGATGACAAACCGCTGACCGATCAGGAAAAAGGCTTCGTGAACACCA4020               CCTCTGTGCCGGTACTGAAATACCTGACCAACGCCCAGAGTATGGGGATGAGCGCCACGT4080               ACCTCCTGCAGGTTTCCGACTTCATCGCGCAGGACCTGATGATCCAGTACCTCCAGGAAC4140               TGGTGAAACAGGCAAGCCTGTCTCTGGCTGGTAAGAACTTCCCGGAAGAGGCCGCTGCGA4200               AGTGCGCGACAACATCATTCATGCCCAGGGACTGCTGGCCGACATGAAGCTGCAGTCTGC4260               GGCAGACCAGAACGCACTGGACGGCATCGACCGCAACATGCAGTACTGCAGCAGCAGGTG4320               TCCACCATTGTTTCAGGCTCCTATCAAAGCAACTATCACTGGGGTGATCGCTGATGCTTG4380               AGATATACACCATTTATGGCGGGGGAATGTGGAAAAACGCGCTGGACGCCGTTGTCACCC4440               TTGTCGGTCAGAATACCTTCCACACCTTAATGCGTATTCGCCCGGCACCTTCGGGGTGCT4500               GGCTGTATTGCTCACTTTCATCAAACAACGTAACCCGATGGTCTTCGTCCAGTGGCTGGC4560               GATCTTCATGATCCTGACGACCATCCTGCTGGTACCGAAACGTTCAGTACAGATAATTGA4620               CCTCTCAGACCCCGGCTGCGGTGTGGAAAACCGATAATGTACCGGTCGGTCTGGCTGCCA4680               TCGCGTCACTGACGACCAGCATCGGTTACAAAATGGCATCGGTGTACGACATGCTGATGG4740               CCAGACCTGACTCGGTAACCTACAGCAAGACCGGTATGCTGTTTGGCTCGCAGATTGTGG4800               CGGAAACCAGTGACTTCACCACGCAAAACCCGGAACTGGCTCAGATGCTGCCGGACTACG4860               TGGAAAACTGTGTGATCGGCGACATTCTGCTGAACGGTAAATACACCATCAATCAGCTGC4920               TCAATTCCACTGACCCGCTGACGTTGATAACCAGTAACCCAAGCCCGCTGCGGGGCATCT4980               TTAAGATGACCTCCACCTCGCGCCAGTTCCTGACCTGTCAGCAGGCGGCAACGGAGATTA5040               AGACGCTGGCGAATACCGACGTCAATCCGGGCAGTGCGACGTTCACCTGGCTGACGCGGA5100               AGGTATTCGGCAACAAGCTGAATGGTGCCTCGCTTCTGCCAACGCTATGGGTGAGAGCTA5160               CGGATTCTTCTATGCCGGGGGAATGACGGCTGCGCAGATCATGAAGAACAACATCACGAA5220               CAGTGCAGTTCGGCAGGGGATTAAGGGTTTCGCCGCTCGCTCATCCGACACGGCTAACCT5280               GCTGAACCTGGCCACCGAGAACGCTGCAACCAAACAGCGTCTCAGCTGGGCTGCGGGTAA5340               TGAGCTTGCCACCCGAACTCTGCCGTTTGCACAGTCCCTGCTGATGCTTATCCTGGTGTG5400               CCTGTTCCCGTTGATGATTGCGCTGGCCGCATCAAATCACACTATGTTTGGGCTGAACAC5460               CCTGAAAATATACATTTCCGGTTTTATCTATTTCCAGATGTGGCCGGTGATGTTCGCCAT5520               CCTTAACTATGCTGCCAACTACTGGCTGCAGAGTCAGTCCGGGGGCACGCCTCTGGTGCT5580               GGCCAACAAGGATGTAGTGGCACTGCAGCATTCGGACGTGGCGAATCTGGCAGGGTATCT5640               GTCGTTGTCCATTCCGGTGCTGTCGTTCGTATCTGACCAAGGGGGCTGCGGCGATGGGCT5700               CTCAGGTGGCAGGCAGTGTCCTCAGTTCGGGCGCCTTCACGTCGGCAGGTGTGGCAGCAA5760               CCACGGCGGACGGGAACTGGTCGTTTAACAACATGTCAATGGACAATGTCAGCCAGAACA5820               AGCTGGATACCAACCTGATGCAGCGTCAGGCCAGCAGACGTGGCAGGCAGATAATGGTTC5880               CACGCAGACGCAGACGCCGGTGGCCATACGGTATCGACGGCTCAGGCGCAATGTCGAATC5940               TGCCGGTGAACATGAAGCTCAGCCAGCTGGCCAGCAGTGGTTTCCAGGAGTCTGCCCGCC6000               AGTCGCAGGTCCAGGCGCAGACGGCGCTCGATGGCTACAACCACAGTGTCACCAGTGGCT6060               GGTCGCAGCTCTCACAGCTGTCTCACCAGACCGGTACCAGCGACAGCCTGACCAGCGGCA6120               GTGAAAACAGCCAGGCCACTAACTCAACGCGCGGCGCGAGCATGATGATGTCGGCCGCTG6180               AAAGCTATGCGAAAGCTAACAATATCTCGACGCAGGAAGCCTATAACAAGCTGATGGATA6240               TCAGTAATCAGGGTTCTGTATCTGCAGGCATTAAAGGTACGGCCGGAGGGGGACTTAATC6300               TGGGCGTTGTTAAGCTT6317                                                          (2) INFORMATION FOR SEQ ID NO:22:                                              (i) SEQUENCE CHARACTERISTICS:                                                  (A) LENGTH: 6914 base pairs                                                    (B) TYPE: nucleic acid                                                         (C) STRANDEDNESS: double                                                       (D) TOPOLOGY: linear                                                           (ii) MOLECULE TYPE: Genomic DNA                                                (vi) ORIGINAL SOURCE:                                                          (A) ORGANISM: Enterobacter cloacae                                             (B) STRAIN: Clinical Isolate ET- 49                                            (xi) SEQUENCE DESCRIPTION: SEQ ID NO:22:                                       AAGCTTTTCGAGTTCGCCATCCGGCAACAGCTCACTGAGCTTTTACGCGCCCAGGGTGCC60                 TTTGAACTCAATTCCCAGCTCAGTAAGGCGGTCCTGAATAATCTCTTTGCGAGATTTTTC120                ACTGGTACCGGCATCAGGTGTTGCAGGTTTCAGCTCGCCACCAGCCTCGCCCTTCATCAG180                CCGGACGTTAGACTTCAGCGCCGGGTGAAGATCTTTCAACTCCACCACGTCGCCAACCTT240                TACGCCGAACCATGGGCGCACAACTTCGTATTTAGCCATGCTGTTTCCTTACGCCAGGTT300                AGCGCCGTAGACAACGCCAGACAGGCCTGATCGTCTGCAGTAATTTGCAGGCCTTCAGCA360                GACATGATCTGGAAGTTGTAGTTAACGTTAGGCAGTGGGCGCGGCAGTGGCACAACGCCA420                ACAGCCATACCCACCAGTGGGGAGATCACGTCACGACGACGAACGTACGCGATAAACTCG480                TTACCGGTCAGCGCGAAGTCATGCGGATTTCTTTCACCGGTGCGAATGGCAGAACAGCCT540                GCAGGAGAGTGCCGCTCACCACACCATTAACTACGTATGGCTGAGCCATATTTGCCCAGA600                TCTCAGGGGAAACCCACATCACATCATACTGAGCTACTTTGTTGGTGCGTGCGGTGGTAC660                CGAATGCTCCTTTACCAAAGAACTCAAAATATTGAGTCGTGGTTGCGCTGGTCAGGTCGA720                TGTTCGCACCACCAGCACCAGAACCGAGGTTAATCTTCTTGGTGTTGCGGTGGTTCTTGA780                TGCCCTGCGCCGGGTAGGACTGAACCTGAATTTTTGAATCGCCGTTCAGGTAGTAGTTGA840                CGCGCTTCTGGTTGAACTTGCGCATCTTCGCCATCTGCGAATCCAGAACCAGATCAATGC900                CTACAGAGTTAAGGCCAGCAGCATGACGCCAGTTAACACCGTAGCCAGCAGTGAACACCG960                GAATCGGGTCGCCATCGCTCGCGTAGTCAGTGTGGTCGAAGGAGAATGGCGCCTGACCAT1020               CGATGCTTACTGACACGTCGTCAGCGATGTCGCCGACCACGTTATACAGCTTGGCGGTTT1080               TACCAACCGGCAGCACGGTCTGAACGCCGATCAGGTCGTTTACGATTTCCATGCCAACTT1140               CCTGATCCCGCAGCTGCAGCACCTGGTTGTCAATCTCAGCCCAGAAGTCACGGGAGAAAC1200               CGCCAACAGCGTTACAAGCCAGCATGTCAGGCGTCATCATTGCGCGGTTAGCTGCAATGA1260               TGGAATCGTTCTGTAGGTTCCACATGTTGCGGTTTGCCCACAGCTCACTCCAGTGCCCGC1320               CGAGGCGGGAGTTAGTCGCCAGCGTCTCTTTAGAGAAGTACATATGTGTTTGTCCTTTTG1380               TTACGCGCCAGCTGCGGCGACAGTGCCAACGCGCATACGCACGCGAATGAAGTCAGTGGT1440               GCTGGCCGCGATGGTGTATTCATCCTGGCTGTAGCCGATCACTGAATCAGTGTCGGATGT1500               GGCAAGGGTAAACTGACCGGCAGTTCCCAGCTTGATCGGGCTGTCTTTTTTATACGCACC1560               AGGCAGGCAGCGCAGCGCCAGCTCACGACCTTCTTCGACGTAGTTACCTACTGCCGAATC1620               CCCGGCAGGGATTTCTTCGGTGATTGTCAGGCCCTGGTGATAACCGACATCGATGATGTA1680               CAGGCGGCCGGTTAGCGCGGTGGCCTGAGCGAATTTATCGGATGAGTTGATGGTTGCGGC1740               GGTGCCAGGAAGCAACCCGGCGGCCGTTGTGCGGGTTTCGGTCTTGTACAGAGACTGACC1800               GTCGATATTAACGCGACGATAACGTGGCATTATTCCGGCTCCTTACTTGAAGTGTTCGTC1860               TGCGGCTGGTGCGCCGGTTTCTTTGTGCTGCTGAGCATTGTTGGTGCCCAGCGACTTGAA1920               CATCGCGTCCAGAGCTTCGCCTGACAGAGCGTTCGCGAGCGATATCGCCATGGACCTTCG1980               CAACCGCTTCGCGCTTTGCTTTCTCTTCGGCACGGGAGTTCGCGGTAAGGGTTTCCGCGA2040               GTTGCTTCTGATTGGCCTGCAGCGCATCAACCTTTTCCGCGAGAGGCTTAATAGCCGCTT2100               CAGTATTGGTCGCAACAGCCTGGCCGATCATGCTGCCGATTTGTTCCAGTTCTTCTTTGG2160               TTAAAGGCATGTCGCCTCCGTTTTGTGGTTTGGTGCAGGCTGTTCCTGCGGTGTGAATAG2220               AGCTTTGAATTGTTAGCGACGACTGCCACCCACGACTCCTGGCGCGCTACTGCGGTTCCG2280               GTATCGTCGATTGTGATCTTCCCGCCATCAGCGAATACCGTAAACCTGAGCATCACCGCC2340               ATTTCGCACGATGACCACCTGCGAGTCAGTGAGTCAGCAACCCAGGCATATTCATCCGTG2400               CCCGGCGCAAACTTGGCTTTGGCTGCCCGATCGAGACGCTGCTCGCGCTCCCGGTAGGAT2460               TCACCCACCAGCGCGCCGGAGTTCGCTTTAAGCGGCTGCGCCAGATCGGCGTTTACCATC2520               AGGCCAACGCCCTGCTCAGGGGTGGCGGCTCCGACTTCGTGCAGTAGGATCGCGTCGTGG2580               TCCATGCTGTGAATCTTCGCCACCCACTCGGCACCCGTAGCTCTCTGTTGTTCGTTAGGC2640               TCAAGCTGGTCGAGGAAAGCGGCGACACTGGTATGAATCGGCGGAACGTCATCGCCGCGC2700               TCGATGGCTGCGACGCGCTCAAGTAGTTCTCGGCCACCTTCAGACTCACCGGCGCGGGCA2760               ACATCAACCCACTTTTCGAGGTAGATACGATTACCGGACTTCTTAACGTTGCGGTTCCAC2820               GCGCCGATATGGCCTGCGTTAATCCCCTCCGGGGAGAAAGCAGACACGAACTGACCATTA2880               ACCTGAGGGTGGCCCAGCGGCGCCAGGGTACCTTCCAGCCCCTTATAGTGGGCGTCGATT2940               TGCTCTTGCGTGTACAAGCCGCCATTCATGACGACGTTAGCTGGAAGTGTGTAGCTCGGC3000               AGCACCAGGTGCTCACGCCCGTTGTATGTTTCGCGCCGGATAGACTGGCTGTTCACCTTT3060               GTGGTGATGTTGACCTGAATATGCTCACCATGTTTCGGTGCCTGGATTGGACGCTGTGCT3120               TCGTGGTTTACCTGGAATTTCATGAGTTATTTCTCCGCCCAGGCGTAACCGCTCGCCTGC3180               ATCGATTTATATTCCTGTTTGAGTTTCGTGATGGTGTCCGGGTATTCCGGCTTGCCGTCC3240               GCATCCACCAGCACCGACTGCTGGCTGCATTTGCAGTTGATGGAGTTGCCATCTTTGCTG3300               TACCAGTCACGCACCTCTTCGTTGGTGTAGAGGTGGGCATGGGCGCACTGCGTGGGTATG3360               TCGCGTTGTCGGCGACAGAGCTGAGATGTGAACCAGCAGCGTTTTAAGGCCGAACAGGTC3420               ATTCGCCTCTTGGTCTTCATCCCACTTGGCCCGGCGCAGCGCGGTAGTCACTTCAGTGCG3480               TGCTATCCGGTTAGCCCGGCGTTTCTCGATGCCGGTCTGGTCTGTCAGGTTGCGGGCAAT3540               GTCCAGAGGATTGAGCCCGCGCCCAACACCATCAGTAAGACACGCGCCATGTCGCGCTTA3600               ACGTCAGCCGTCAGCCCCTTCATTTCCTCAAATACACGCGCATGCACCAGCGCCATGCGT3660               TTCTGATACTGGTCGCTTGCGAGGATGGAGGCCAGCGACTCACGCCCGGCTGCGTACACC3720               GGGGATTGCTGACTGAGGTTGTAGAACGACTGCCCGGTCCCTTTTTCCGAAGCCAGATCG3780               ATGTACTCGTAAAACCACAGGTCGTAATCGCCACCTTCAAGCAGTACCTGATCAACCAGG3840               TAACTGGCATCGTTCAGGATGATGGAGAGTAGCATTGGGTTTAGCTGGTATTCGTATCTG3900               GCGTTTACTGCGAGGGAGGAAGGTATTTTGTTGAGTGCTGATTTGTACGCCTTGCCAATC3960               TTATTCATCCGCCTGGCGAAGTCTTTCATTGCCCGGCGTTCCAGCGCATCGGCTCCGGTC4020               GGATCCTGATAGTTACGCGGCAGAATCGGTGGCTTCGTCTTCTTCGTCGCCATCCTCTTC4080               TCCTAATGGAAATTCATCGACGTTTTCATAACCGGCAGCAGTGCGGAATTTCTTCACGAC4140               TAAAGGCTGGTTTTTCTCCGCTCCCCTGGAACGTCTGGTTAATCTCTGCCATGGTTTTGG4200               CATTTGCGAGTTTCTCAGTTCCAGTCTGTTCGTTGAGGTCATCCCAGATAACCGTCTTCT4260               CGCTGACTGCATCAATAATTTTCAGGTCGATGAGCTTGTCACTGAAGTCTTCAATTTCGA4320               ATGACAGGTCACCGCGCCGTGACTGGCAGCGCGCGTTGAAATATTTCTGATCCTCGGTGC4380               TTGCCCTTTCACCCGTCTGCATCCCAACCAGAACCTTCACAGGGATATCAACAGATGCAG4440               CGAAGGTTTGCAGGTTGACGTTATAGGTCGCTGACGGATCCGCTACAGCTGTGACCAGTG4500               GTGTGACTGTAGCCCCTTGGGTTGTCATCAGAACATCGTTACCACGGTTCATTTCCCCGG4560               CAACTTCGTTAAACTTATCCTGCAACTCGTCCATGTCACGCCATAAAGTGACGCGAGATT4620               GTTGAAATCGATTTCCTTCTCAAAGTTGACATTAAGCTGCCGCGCGGCGTTCTTTAGGAA4680               TGACTCACCAGAACCACCCTCGACCTTCTCAAGGCTGACGCAGGCGTTATAGCCAGGCTC4740               AAGGAAGCCAATAGCATCATTAGAATAGTCACCAAGGATAAAGACGCGATCGGGATGTAC4800               GAAGCGCTGATTAGTTCCACCGCTTGGAAGGCTCTCAACATATTTCCACTGCTTTGGCTG4860               CCCGTAGCCTGCCGATTTCTGGTCAGTTACCCACTCGCTGACTGTTAATGACCCAGCCCA4920               TGCGATCGTAACCTTTTTTAGTGACTTGCCACGAACAACAGGCTGATCCCATGTTCTGGA4980               ATCATTGATATGCAGCAGGATACCCGCATAACGTCCGACCTGTCGGCGGCGGTCTGCTTC5040               AGCAAAAGCCCGCCAAAGGCGCTTTGTGAAAACCTTTTTGGTGTTCTTCTCCCAGGCAGT5100               TTCATCCTTACTCTCGTCGGCATCATCACCCTCGATGATTTCCGGGTTGGTCTGCCAGCA5160               CTTGCCCACCAGCTTCTCTACTGCGCCGTGGGCTATTCCACCGCGACGATACAGTGCGTA5220               GAGGTTTTCGTAAGTGACCTGCTCAGGGAATCCATACTCGCACCATGCGGAATGGCGCTT5280               ATTGTCCAGCCCCATTGTAGGCGCCAACAGCCCCATACGGGCACGGGCCATCCGCGCATC5340               GTTCAACGCATGGTTGACGGCGAGAGTTAATTTGTCAGTCATGGTTTGTCCGTTGGTGGA5400               TTTAAGGCATAAAAAAAGGCCGCTTTGGCGACCTTGTGGCTATTTAAAAAGCTAAACTCT5460               GTTGAACGAAATAAACATAATCTGCTCAGGCTTAACGCCATAATCACTTGCCAACTTCTG5520               AGTGCACTCAATTAAGACAGTTGATGCAGATTTCGAAGAGCTTGCACCATAAATTTCGAA5580               GTTTTCAAATACTCCGCCGTTGGTGTGGTAAATCTTATATGACATAAACCAATCATTCAT5640               AATATCTACTCCCTTACAGAATTGAGTAGATATTATCGGCAAGTGCATATGTTTCTTTAA5700               ATTATCTCAACCTTTTCGGGATCATCATCCCGGCCATCTGGCCCTTACGTTTAATGTGTC5760               CGTCGAGGCTGTAGCGAATACCGTCCCAGCAGTGTTCGTAACCGTCTGCCAGTTTAGGCA5820               ATACCTCGCCGGTGATGCGGTCCGTTTTGTAGGACCACATGCGGGCCTCTCTCGCCACAT5880               TCTTGCAGCGAGGATGGATAATGATTTCGTCAAAGCCGCGAAGATGCGCGATACCGTCCT5940               CAACACTCCCCTGCCATTTCTCGGCAGCCGAGATGTTGAAGCCCTGGCGCTTGAGATAGC6000               TGATAGTCTCGGGTCGGGCGGAGTCGGCCTTGATGGGCCAGTCACGCGATCCGGGGATTG6060               TGTCGTATAGCTCTGGCATATGGTCGAGCTCTGTCTGCTGACCGTATGCCTCGTATTCGA6120               TGTACAGCCGGTTGTGCAGGATGAACGAGCGCACCAGCGTGTTAGGGTCTTTGGCGAAAC6180               CGAAGTCAGCACCGAAGAAAAGGCGATCGGCCTCTTTCCATAGCTGGTCCGAGAACTCAG6240               CGATCCGGTATTTACCGGCCAGCACCTGCTTATCAGAGTTTTCGAGGTAAGCACCTTCCC6300               AAACCCACGCGTATGTTGCCGGGTCAAGGCGGCGCTGATCGTTCTGTCGCTCACCTTCCA6360               GCACGTCGGGGAACCATGGATTATCCGTGTAGTTCATCTCAACGTGATACAGTCGTCGCC6420               AGCCTCTTTACGGAAACGCTTATCCGTGCGCTGCCGTCGCGCTCCGGGTTCCATGTCACC6480               CAAATCTCTGAACCTTCCTCACGAACGGTCGGGCTCAGCTTCTGCCAGGCTATTTCGCTG6540               ACTGATTCAGCCTCATCAACCCAACAGAGCAAGATGCGCGCTTTCGACTTGATGCTGTCG6600               AGGTTATGCCGCAGACCGCAGAACACGTAGTTAACGCTCTTGTCGATGGTGCGGATGTAC6660               TTCTCGCCGATATCAAAGTTGGAAGCCAGCCAGGGAACAGACAGGATAGCCTGTTTCACC6720               TCCTGCATACTCGACTCTTCCAGTGAGTTCATGAATTCACGCGCACAGAGCACCACGCCG6780               CTTTCACCGTTCATCATCGACTGATACGCCTTTACGGCTGTCATCAGCGCAAAAGTGCGC6840               GTCTTGGCACTACCACGCCCACCATGCGAGCACCGGTAACGCTTATTCTCGGCGATGAAC6900               AGTGGCGCAAGCTT6914                                                             (2) INFORMATION FOR SEQ ID NO:23:                                              (i) SEQUENCE CHARACTERISTICS:                                                  (A) LENGTH: 5975 base pairs                                                    (B) TYPE: nucleic acid                                                         (C) STRANDEDNESS: double                                                       (D) TOPOLOGY: linear                                                           (ii) MOLECULE TYPE: Genomic DNA                                                (vi) ORIGINAL SOURCE:                                                          (A) ORGANISM: Klebsiella pneumoniae                                            (B) STRAIN: Clinical Isolate KI- 50                                            (xi) SEQUENCE DESCRIPTION: SEQ ID NO:23:                                       AAGCTTATTCCACGCTGGAGGCGTCCGGGATTATCGGCGTCAACGCTATCGCCGGCATCG60                 CCGGGACCATCATCGCCGGCATGCTCTCCGACCGCTTTTTCAAACGCAACCGCAGCGTGA120                TGGCCGGATTCATCAGCCTGCTGAACACCGCCGGCTTCGCCCTGATGCTCTGGTCGCCGC180                ACAATTACTACACTGATATTCTGGCGATGATTATCTTCGGGGCCACCATTGGCGCTCTGA240                CCTGCTTCCTTGGCGGGCTGATCGCCGTCGATATCTCTTCGCGCAAGGCCGCCGGGGCCG300                CGCTCGGCACCATCGGCATCGCAGCTACGCCGGCGCCGGCCTGGGCGAGTTTCTCACCGG360                GTTCATTATTGATAAAACGGCTATCCTTGAAAACGGCAAAACGCTGTATGATTTCAGCAC420                GTTGGCGCTGTTCTGGGTGGGTACGGTCTGGGTTCNGCGCTACTCTGTTTTACCACTGCC480                GCCATCGTCGCCCGGCGCCATGCCGTCGAACGGCAGACCTCGTTCTCCTCATAACCGATT540                AACGAATAAGGAAGAAGATATGATGCCTGCAAGACATCAGGGGCTGTTACGCCTGTTTAT600                CGCCTGCGCGCTGCCGCTGCTGGCGCTGCAATCTGCCGCCGCCGCGGACTGGCAGCTGGA660                GAAAGTGGTCGAGCTCAGCCGCCACGGTATTCGTCCGCCGACGGCCGGCAACCGGGAAGC720                CATCGAGGCCGCCACCGGCCGACCGTGGACCGAGTGGACCACCCATGACGGGGAGCTCAC780                CGGCCATGGCTATGCCGCCGTGGTCAACAAAGGGCGTGCGGAAGGCCAGCATTACCGCCA840                GCTCGGCCTGCTGCAGGCCGGATGCCCGACGGCGGAGTCGATATACGTGCGCGCCAGCCC900                GCTGCAGCGGACGCGAGCGACCGCCCAGGCGCTGGTGGATGGCGCCTTCCCCGGCTGCGG960                CGTCGCTATCCATTATGTCAGCGGGGATGCCGATCCCCTGTTTCAGACCGACAAGTTCGC1020               CGCCACGCAAACCGACCCCGCCCGCCAGCTGGCGCGGTGAAAGAGAAGGCCGGGGATCTG1080               GCGCAGGTCGGCAGGCGCTGGCGCCGACCATCCAGCTATTGAAACAGGCGGTTTGTCAGG1140               CCGATAAGCCCTGCCCGATCTTCGATACCCCGTGGCAGGTCGAGCAGAGCAAAAGTGGGA1200               AGACCACCATTAGCGGACTGAGCGTGATGGCCAATATGGTGGAGACGCTGCGTCTCGGCT1260               GGAGTGAAAACCTGCCTCTCAGCCAGCTGGCGTGGGGCAAGATCACCCAGGCCAGGCAGA1320               TCACCGCCCTGCTGCCGCTGTTAACGGAAAACTACGATCTGAGTAACGATGTGTTGTATA1380               CCGCGCAAAAACGCGGGTCGGTGCTGCTCAACGCTATGCTCGACGGCGTCAAACCGGAGC1440               GAATCGAACGTACGCTGGCTGCTGCTGGTGGCCATGACACCAATATCGCCATGGTGCGCA1500               CGCTGATGAACTTTAGCTGGCAGCTGCCGGGCTACAGCCGGGGAAATATCCCGCCGGGCA1560               GCAGCCTGGTGCTGGAGCGCTGGCGCAACGCGAAGAGCGGAGAACGCTATCTGCGGGTCT1620               ATTTCCAGGCCCAGGGCCTCGACGACCTGCGTCGTCTGCAGACGCCGGACGCGCAGACCC1680               CGATGCTGCGTCAGGAGTGGCATCAGCCGGGCTGCCGTCAGACCGATGTCGGTACGCTGT1740               GTCCCTTCCAGGCGGCTATTACCGCCCTCGGTCAGCGTATCGACCGATCATCCGCCCCGG1800               CGGTAGCATGGTCCTGCCGTAGCGGCGCGGTGTTTGTCCGGGCCCGGGAAAACCTTTTTT1860               TCCAGGCCGGCACGACGTCCGTTATCCGTTGTCCGGCGCAAACGCCCCGGCGGCGACCTG1920               CGCCGGGGTGACACCCGCTGTCCAGCACCCAGCCGCTTATCAGCCCAGCAGGCGTGACGT1980               CGAACGCCGGATTGTAAACGGTGGCCCCCGTCGGCGCCCACTGTACCGCGCCGAAGCTGC2040               CCGCCACTCCGGTCACTTCCGCCGCCGCGCGCTGCTCAATGGGGATCGCCGCCCCGTTCG2100               GGCAATGGCGGTCGAGGGTGGTCTGCGGGGCAGCGACGTAAAACGGGATCTGGTGATAAT2160               GGGCCAAAACCGCCAGAGAATAGGTGCCGATTTTATTCGCCACGTCGCCGTTGGCGGCGA2220               TACGGTCGGCGCCGACCCACACCGCATCCACCTGCCCCTGCGCCATCAGGCTGGCGGCCA2280               TTGAATCGGCGATCAGCTGATAGGGCACGCCCAGCTCGCCCAGCTCCCAGGCGGTTAAAC2340               GACCGCCCTGCAGCAGCGGCCGGGTTTCATCAACCCATACGTTGGTCACTTTTCCCTGCC2400               GGTGCGCCAGCGCGATAACGCCGAGGGCGGTCCCTACCCCGGCGGTCGCCAGGCCACCGG2460               TGTTGCAGTGGGTCAGCAGTCGACTGCCGGGCTTCACCAGCGCACTGCCCGCCTCAGCGA2520               TGCGGTCGCACAGCTGTTTATCTTCTTCGACCAGACGCAAGGCTTCCGCTTCCAGCGCCT2580               GCGGGTAATCTCCGGGCCAGCGCTGCTTCATGCGATCAGATTATTCATCAGGTTGACCGC2640               CGTCGGCCGCGCCGCGCGCAGTCTCCAGCGCCTGCTGGAGTGCATCCCGGTTCAGGCCGC2700               GCTGGGCCAGCAGGGCCAGCAGCAGGCTGGCGGACAGGCCAATCAGCGGCGCGCCGCGCA2760               CCCCGCAGGTATGAATATGGTCCACCAGCAGCGCAACGTTATCCGCCGCCAGCCAGCGTT2820               TTTCCTGCGGCAAGGCCTGCTGGTCGAGAATAAAAAGCTGATTTTCACTCACCCGCAGGC2880               TGGTGGTCTGTAATGTCTGCATGTCGTTAAATCCCTGTTGCGTTGTTGTATCACATTGTG2940               TCAGGATGGAATCCAGAAGTATAGACGTCTGAACGGCTTAATCAGAATTCGAGGATCGAG3000               GCAATGTCGCAATACCATACCTTCACCGCCCACGATGCCGTGGCTTACGCGCAGAGTTTC3060               GCCGGCATCGACANCCATCTGAGCTGGTCAGCGCGCAGGAAGTGGGCGATGGCAACTCAA3120               TCTGGTGTTTAAAGTGTTCGATCGCCAGGGCGTCACGGGCGATCGTCAAACAGGCTCTGC3180               CCTACGTGCGCTGCGTCGGCGAATCCTGGCCGCTGACCCTCGACCGCGCCCGTCTCGAAG3240               CGCAGACCCTGGTCGCCCACTATCAGCACAGCCCGCAGCACACGGTAAAAATCCATCACT3300               TTGATCCCGAGCTGGCGGTGATGGTGATGGAAGATCTTTCCGACCACCGCATCTTGCGCG3360               GAGAGCTTATCGCTAACGTCTACTATCCCCAGGCGGCCCGCCAGCTTGGCGACTATCTGG3420               CGCAGGTGCTGTTTCACACCAGCGATTTCTACCTCCATCCCCACGAGAAAAAGGCGCAGG3480               TGGCGCAGTTTATTAACCCGGCGATGTGCGAGATCACCGAGGATCTGTTCTTTAACGACC3540               CGTATCAGATCCACGAGCGCAATAACTACCCGGCGGAGCTGGGAGGCCGATGTCGCCGCC3600               CTGCGCGACGACGCTCAGCTTAAGCTGGCGGTGGCGGCGCTGAAGCACCGTTTCTTTGCC3660               CATGCGGAAGCGCTGCTGCACGGCGATATCCACAGCGGGTCGATCTTCGTTGCCGAAGGC3720               AGCCTGAAGGCCATCGACGCCGAGTTCGGCTACTTCGGCCCCATTGGCTTCGATATCGGC3780               ACCGCCATCGGCAACCTGCTGCTTAACTACTGCGGCCTGCCGGGCCAGCTCGGCATTCGC3840               GATGCCGCCGCCGCGCGCGAGCAGCGGCTGAACGACATCCACCAGCTGTGGACCACCTTT3900               GCCGAGCGCTTCCAGGCGCTGGCGGCGGAGAAAACCCGCGACGCGGCGCTGGCTTACCCC3960               GGCTATGCCTCCGCCTTTCTGAAAAAGGTGTGGGCGGACGCGGTCGGCTTCTGCGGCAGC4020               GAACTGATCCGCCGCAGCGTCGGACTGTCGCACGTCGCGGATATCGACACTATCCAGGAC4080               GACGCCATGCGTCATGAGTGCCTGCGCCACGCCATTACCCTGGGCAGAGCGCTGATCGTG4140               CTGGCCGAGCGTATCGACAGCGTCGACGAGCTGCTGGCGNGGGTACGCCAGTACAGCTGA4200               GTGCGCCTGTTTCCCTCACCCCAACCCTCTCCCACAGGGAGAGGGAGCACCCCCTAAAAA4260               AGTGCCATTTTCTGGGATTGCCCGGCGNGNTGCGCTTGCCGGGCCTACAGATAGCCGCAT4320               AACGGTTTGATCTTGCACTCTTTCGTAGGCCGGGTAAGGCGAAAGCCGCCACCCGGCAGA4380               CATGCGAGTACAATTTTGCATTTACCTTACCCTCACCCCAGATACTCAATCACCGATAGC4440               CCGCCGTTGTAATCGGTGCTGTAGATAATGCCTTGCGCATCGACAAACACGTCACAGGAC4500               TGGATCACCCGCGGGCGGCCGGGACGGGTATCCATCATTCTCTCAGCGCAGCCGGCACCA4560               GCGCCCCGGTCTCCAGCGGGCGATACGGGTTGGAAATGTCGTAAGCCCGCACGCCGGCAT4620               TCTGATACGTGGCAAAAATCAGCGTTGAGCTGACAAAGCTCCCCGGCCGGTTCTCATGCA4680               GGTTGTGCGGACCGAAATGCGCCCCTTTCGCCACGTAATCCGCTTCATCCGGCGGCGGGA4740               AGGTGGCGATGCTCACCGGGTTGGTTGGCTCGCGGATATCAAACAGCCAGATCAGCTTCT4800               CGCCGTCCTCCTGGTTATCGAGCACCGCTTCATCCAGCACCACCAGCAGATCGCGATCCG4860               GCAGCGGCAGCGCGGTATGCGTTCCGCCGCCGAACGGCGGGCTCCAGTTGCGATGGCTAA4920               TCAGCCTCGGCTGGGTACGGTCTTTGACATCCAGCAGCGTCAGGCCGCCGTCGCGCCAGC4980               TGCGTAGGCGTATCCCCGGCAATAATGGCGTGATGCAGCGCATAGCGTTTGCCCTGCGGC5040               CAGTCCGGTGTTTCACCGCCCGCCTGGTGCATCCCCGGCAGCCACCAGCGCCCGGCTACT5100               TCGGGCTTACGCGGATCGGCCAGATCGATGGTCAGGAAGATGTAGTCGGTAAAACCGTCG5160               ATCAGCGCAGACACATACGCCCAGCGCCCGCCGACGTACCAGATGCGGTGAATACCGATG5220               CCGTTAAGCGACAGGAAACTGATTTCCCGCGCTGCGCGGGAGTGGAAATATCAAAGATGC5280               GCAGCCCGGCGCTCCAGCCCCTGTCCTGCACATCGCTGACCGTGTCACCCACCGAGCGGG5340               TGTAGTACACCTTCTCATCAGCAAAACGGGCGTCAGCAAACAGATCCCGGGCGTTGATCA5400               CCAGCAGCAGATCGTCATGCGCCTGGAGTGCACGTTCCAGGTGCCCGGCGGCGCGGCAAT5460               ATAGTTGACGGTGGTGGGCCGGGTCGGATCGCGAACATCGACCACGGAAAAACCCTGCGA5520               CACCATATGGCCGATATAGGCGAATCCGCGGTGCACCATCAGCTGCACGCCGTCCGGACG5580               ACCGCCCTGATCGCTATGGCCAATCAGCCGCATATTGCGGCTGTATTCGGGGGAAGGTAA5640               TGCTGACATAGGGGATCCCTCTCGCCCGGTGGCATGGTTTTCCCCCCTCTCCTGCGGAGA5700               GGGCCGGGGCGAGGGCACCAGGCCGCCGCCCACCGCCACCCGGCTTGATTTTATTTGTTC5760               TTCGCTTCCAGCGTCGCGAACCACGGCGCGATAAAGTCTTCGGTCTGGCCCCAGCCAGGG5820               ATAATTTTCCCCAGCGACGCCACGTTTACCGCTCCCGGCTGGGCCGCCAGCAGCGCCTGG5880               GGAATCGCTGCCGCCTTGAAGTCGTAGGTGGCTGGCGTCGGCTCGCCGGCGATCTTGTTG5940               GCGATCAGCCGCACGTTGGTCGCGCCGATAAGCTT5975                                        (2) INFORMATION FOR SEQ ID NO:24:                                              (i) SEQUENCE CHARACTERISTICS:                                                  (A) LENGTH: 24 base pairs                                                      (B) TYPE: nucleic acid                                                         (C) STRANDEDNESS: single                                                       (D) TOPOLOGY: linear                                                           (ii) MOLECULE TYPE: other nucleic acid                                         (A) DESCRIPTION: /desc = "primer"                                              (xi) SEQUENCE DESCRIPTION: SEQ ID NO:24:                                       CGACGTTGTAAAACGACGGCCAGT24                                                     (2) INFORMATION FOR SEQ ID NO:25:                                              (i) SEQUENCE CHARACTERISTICS:                                                  (A) LENGTH: 17 base pairs                                                      (B) TYPE: nucleic acid                                                         (C) STRANDEDNESS: single                                                       (D) TOPOLOGY: linear                                                           (ii) MOLECULE TYPE: other nucleic acid                                         (A) DESCRIPTION: /desc = "primer"                                              (xi) SEQUENCE DESCRIPTION: SEQ ID NO:25:                                       CAGGAAACAGCTATGAC17                                                            __________________________________________________________________________ 

We claim:
 1. A probe composition for detecting Staphylococcus aureus, wherein the probe composition consists essentially of(a) the DNA of any one of SEQ ID NOS:1 through 4, or (b) the complement of (a).
 2. A method for detecting the presence of Staphylococcus aureus in a sample comprising the steps of contacting nucleic acid from said sample with the probe composition of claim 1 and detecting hybridization of the nucleic acid from said sample with DNA in said probe composition as an indication of the presence of Staphylococcus aureus. 